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Tarring one journalist or media outlet as an "enemy of the people" tars us all, because we are all trying to do the same thing: report the facts. The Daily Free Press 166
Supporters of right-to-try argue that the legislation is needed because most terminal patients are too sick to be selected to participate in clinical trials and it takes too long for promising treatments to be approved.Joffe argued that the right-to-try approach to providing access to unapproved drugs early in their development could put patients in harm's way, as patients receiving the drug are often in very fragile health, doctors often lack the information needed to administer the drugs safely, and little may be known about their risks and benefits, he said.Joffe pointed to certain stem cell therapies as treatment approaches that appear promising but have turned dangerous when unregulated."Another thing I'm worried about is that there's going to be a bunch of shady actors that are going to pop up that are going to start to try to take advantage of the right-to-try law to say 'we can provide these sort of experimental therapies, if you want to call them that, to patients without needing to go through the FDA,'" Joffe said."We've already seen some of that in the stem cell clinics popping up around the country that try to provide stem cell treatments for a host of problems: eye problems, heart problems," he said. "While there are legitimate efforts to develop effective stem cell therapies, a lot of these clinics that are popping up around the country that are poorly regulated are taking people's money and they are hurting people."On the other hand, the treatments available under right-to-try laws are already in clinical trials, Coleman said, adding that "this law isn't replacing the existing FDA expanded access program; it's just opening up another avenue.""No person is going to be forced to take an investigational drug. No doctor is going to be forced to request an investigational drug, and no drug company is forced to provide an investigational drug, if they don't think it's the right fit for a patient," she said."It's only for people who say, 'I understand the risk. I know this drug is not fully approved. It may not help me, but my doctor and the drug company think it could, and I want to try,'" she said. "Basically, if the FDA says that a drug is safe enough to be used in trials on humans, then it's safe enough for a dying person to make their own choice about whether or not they would like to try it when they can't get into a clinical trial." 2395

Some form of retaliation appears likely from China, with which the US traded more goods than any other country last year. Beijing will take "firm actions" if the tariffs inflict losses on Chinese businesses, Commerce Ministry official Wang Hejun said Friday. 258
So many people are dying, and there is a need for developing medications, Hurd said.For their study, published Tuesday in the American Journal of Psychiatry, Hurd and her colleagues looked at 42 adults who had a recent history of heroin use and were not using methadone or buprenorphine.Recruited from social services groups, halfway houses and treatment centers, the participants had used heroin for an average of 13 years, and most had gone less than a month without using. They had to abstain from any heroin use for the entire trial period.The participants were divided into three groups: one group given 800 milligrams of CBD, another 400 milligrams of CBD and another a placebo. All the participants were dosed once daily for three consecutive days and followed over the next two weeks.During those two weeks, over the course of several sessions, the participants were shown images or videos of nature scenes as well as images of drug use and heroin-related paraphernalia, like syringes and packets of powder that resembled heroin. They were then asked to rate their craving for heroin and their levels of anxiety.A week after the last administration of CBD, those who had been given CBD had a two- to three-fold reduction in cravings relative to the placebo group. Hurd said the difference between the two CBD groups was insignificant.The research team also measured heart rate and cortisol, the "stress hormone," and found that the levels in those who got CBD were significantly lower than those who hadn't received the drug.Promising potentialThe researchers used 1573
The act is the latest rock-related vandalism this year after reports in La Mesa of someone hurling rocks into windows in January. 134
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