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SAN DIEGO (KGTV) - The city is running behind on a project to restore an iconic bridge that borders Hillcrest and North Park.Now, people in the area are growing frustrated at the construction on the Georgia St. bridge that's causing traffic delays and drivers to use surrounding neighborhoods as shortcuts."Traffic is very very bad because of te bridge, and I have to go around to buy stuff for my shop, and it's taking me longer to get where I want to go," said Milan Misic, who lives in the area and owns the Balboa Perk coffee and antique shop. The city is restoring the 103-year-old bridge so it can withstand an earthquake. The city broke ground on the million project in July 2016, saying it would take a year. But now it won't be finished until next spring.A city spokesman says the delays are because of weather, and unanticipated cobbles and deposits crews discovered in the bridge walls, making drilling more difficult.He added that there is no threat to public safety and it will not raise the cost.You can track the project on the city's website.   1092

SAN DIEGO (KGTV) — The County Clerk Office plans to hold more than 100 wedding ceremonies Friday, as couples crowd the offices to make their Valentine's Day a memorable one.Staff plan to issue marriage licenses and perform ceremonies throughout the weekend, with more than 100 on the most romantic day of the year alone.“We are excited to offer walk-in services at our historic downtown office on the waterfront for Valentine’s Day and don’t want couples to miss their chance at Valentine’s Day wedding,” said San Diego County Clerk Ernie Dronenburg.RELATED:San Diego dog groomer to set people kissing dogs world recordSeven couples to tie the knot at Imperial Beach Soapy Joe'sSDG&E: Keep Valentine's Day Mylar balloons away from power linesCeremonies are available on a walk-in basis at the downtown clerk's office only, but couples are strongly encouraged to schedule a time. Appointments are required at the county's Chula Vista, San Marcos, and Santee locations.The downtown offices will be open 8 a.m. to 5 p.m. for the marriage license and ceremonies. Wedding ceremonies can be done at the office's Waterfront Park or inside one of the County Administration building's ceremony rooms. 1199

SAN DIEGO (KGTV) - The City of San Diego is close to completing a project that will protect a popular Ocean Beach walking path from erosion.People who live along Orchard Avenue say the pathway that goes along the coast has been falling apart in the past few years, as tidal surges wear away the concrete."It was falling apart. The sidewalk's coming up, you could have tripped," says Tony Nieves, who lives on the corner nearby. "It's nice to see something done about it."Over the winter, the City started construction on a 3,000 project to rebuild the walkway and add break rocks and rip rap to protect it. It's part of a bigger plan to revitalize staircases and walkways along the coast to improve beach access, which the city started working on in 2008.Rainy, windy weather delayed the Orchard Avenue part of the project, which was supposed to be completed by the start of spring.This past week, the city installed large, man-made rocks to the coast to break up waves. They also added green metal cages around them, leading people to fear they'll get so big they may block views."I come down here most nights that I'm not working, just to catch the sunset," says Brittany Hagedorn. "Living a block away makes it easy."In a statement, the City told 10News the boulders will get another layer of concrete above the cages and they hope to have the project completed before Memorial Day Weekend.In the meantime, people who live nearby will have to wait to use the path again.The full statement from the City of San Diego is below:"The man made boulders being constructed are part of the project to reconstruct the beach access walkway at Orchard Ave. The boulders are intended to protect the newly-installed sidewalk, because this section of sidewalk has previously been seriously damaged by tidal surges. After the cages are complete, the boulders will be covered in concrete so as to blend in with the surrounding rip rap. We expect that the boulders will be completed next week, weather permitting." 2011

SAN DIEGO (KGTV) — The former home of San Diego Padres icon Tony Gwynn has finally found a buyer."Mr. Padre's" Poway home, that had since been foreclosed, was sold on Dec. 13 for ,429,500, according to Realtor.com. The two-acre residence was placed on the auction block in June starting at .2 million. The posted legal notice said that .5 million was still owed on the home.After the auction failed to find a new owner, the lender took control of the property.RELATED: Family of MLB legend Tony Gwynn settles tobacco lawsuitWhen the home remained empty, suspicious activity and reported squatters took up residence inside the estate. In January, the San Diego County Sheriff's Department said they had received nearly half a dozen reports about trespassers at the address over the past few weeks.Realtor celebrity reporter Erik Gunther said the steady price cuts on the property encouraged the new buyer to "take a swing" at the home."After a drawn-out debacle involving squatters and foreclosure, the former home of Hall of Famer Tony Gwynn finally has a new owner," Gunther wrote. "The bank whiffed with their initial price of .12 million, but a steady number of price cuts over the past few months finally encouraged a buyer to take a swing at rehabbing the baseball legend's home."The 7,370-square-foot home features seven bedrooms, 5.5 baths, living room with fireplace, a spacious kitchen and dining room, and its grounds include a basketball court and a pool with a spa. Bad investments by Gwynn caused the MLB legend to file for bankruptcy in 1987, which may have played a role in difficulties holding on to the property after his death from cancer in 2014. The Gwynn family had owned the residence since 1991 for the bank took ownership, according to Realtor. 1784

SAN DIEGO (KGTV) — The Department of Defense has awarded a San Diego biotech company up to million to help develop a next-generation drug to fight COVID-19.Sorrento Therapeutics calls the drug a “rapid countermeasure” against the disease, one that might serve as a vaccine substitute in certain populations or a critical stopgap tool if the virus mutates.“With this, we have a new platform potentially that can respond very quickly to any type of emerging threat,” said CEO Dr. Henry Ji.Sorrento is trying to become the first company to develop an approved DNA-encoded monoclonal antibody treatment. The approach is similar to the experimental monoclonal antibody treatment used on President Trump, but Sorrento’s concept is a more advanced version that offers several benefits.Sorrento’s drug is designed to be used as either a treatment in infected patients or a fast-forming layer of defense in healthy people. The company said its solution should be cheaper and easier to deploy than existing monoclonal antibodies, while offering vaccine-like protective effects that last for several months rather than just two or three weeks.Antibodies are one of the body’s key defense mechanisms. They seek out pathogens and bind to them, marking the invader for destruction like ground troops marking an enemy base for an airstrike. In some cases, antibodies can even neutralize an invader themselves by blocking its method of entry into cells.Monoclonal antibodies are antibodies designed by scientists to neutralize a pathogen. They are hand-picked, genetically modified super antibodies that are cloned in labs.However, the process of growing these super soldiers in the lab is difficult, transporting them requires a cold chain, and as a result, monoclonal antibodies are among the most expensive drugs in the world.Instead of giving people an infusion of pre-made antibodies, Sorrento’s idea is to give people a shot of DNA that instructs some of their cells to churn out perfectly pre-designed antibodies.“It's much easier to make enough DNA to treat a large number of people than it is to make enough protein to treat a large number of people. That’s just a fact about manufacturing,” said Dr. Robert Allen, Sorrento’s chief scientific officer on the project.Dr. Allen said the company is hopeful the drug will induce cells to make protective antibodies for six months or more.This DNA approach to an antibody treatment has never been approved for any disease but other companies are working on their own versions of it. Another biotech with ties to San Diego, Inovio Pharmaceuticals, became the first company to test this approach in humans in 2019 for a drug targeting the Zika virus.Sorrento’s approach is similar to the way DNA vaccines work, but it cuts out intermediary steps and jumpstarts the production of antibodies, rather than leaving the production of antibodies up to the body’s immune system. The result is that protective antibodies can start circulating in days after injection rather than weeks, the company said.“What this is capable of doing is it bypasses the need for the immune system,” said Dr. Mark Brunswick, Sorrento’s senior vice president for regulatory affairs.The drug is unlikely to replace a vaccine in most situations because vaccines can produce other defense mechanisms like T-cells that work in conjunction with antibodies. But the drug might work better than a vaccine for the elderly and others with weakened immune systems who are unable to produce a robust number of antibodies on their own, Brunswick said.Still, the company still has a lot of pre-clinical work and testing to go. Sorrento is hoping to have the drug ready for human trials in four to six months.By then, vaccines from Pfizer and Moderna will likely be widely available, but Dr. Ji said the world needs to prepare for the possibility this virus will mutate.“When you vaccinate hundreds of millions, potentially billions of people, the virus is under tremendous evolution pressure,” he said. “It will escape. It’s guaranteed that the virus is going to mutate and escape all of the vaccines we’re trying to create.”If it does, he said Sorrento will be ready to rapidly deploy its DNA-based countermeasure. 4223

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