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John McCain was admired by supporters and adversaries for his bravery as a military warrior and his courage to rise above party politics.He died Saturday at age 81.Here are some of the late senator's more memorable comments: 232

Johnson & Johnson announced it has paused its coronavirus vaccine trials on Monday following an “unexplained illness” among one of its participants.Johnson & Johnson stressed that adverse events during trials are expected, and a pause gives researchers an opportunity to review all of the medical information before moving forward with the trial. Johnson & Johnson added that it’s not always immediately known if the affected person received a placebo or a study treatment.Among the trials paused was Johnson & Johnson’s multi-country “ENSEMBLE” vaccine, which entered Phase 3 testing in September. Johnson & Johnson said last month that its goal was to seek an emergency use authorization approval in early 2021.The FDA noted that a vaccine candidate must be at least 50% effective to receive emergency use authorization. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit.According to the FDA, a typical Phase 3 trial would take one to three years.“NIH is committed to supporting several Phase 3 vaccine trials to increase the odds that one or more will be effective in preventing COVID-19 and put us on the road to recovery from this devastating pandemic,” said NIH Director Francis S. Collins, M.D., Ph.D. “We also know that preventing this disease could require multiple vaccines and we’re investing in those that we believe have the greatest potential for success.” 1554

JACKSON, Miss. (AP) — Mississippi lawmakers are taking steps to erase the Confederate battle emblem from the state flag. The symbol has come under criticism amid nationwide protests against racial injustice. The House voted Saturday to file a bill to remove the symbol that many see as racist. A committee would design a new flag including the words “In God We Trust.” Voters would decide in November whether to endorse that design. Mississippi has used the same flag for more than 125 years. Religious, education, sports and business leaders are pushing legislators to remove the Confederate symbol. Republican Gov. Tate Reeves said Saturday that he will sign a bill to change the flag. 695

KANSAS CITY, Missouri — A handcuffed man in police custody jumped to his death from a bridge on Interstate 435 just south of the Missouri River and the Missouri 210 exit, according to the Kansas City, Missouri Police Department. 246

KERNVILLE, Calif. About 45 miles to the west of the quake's epicenter, San Diegan Jose Blanco was watching television on the couch in his parents' home. His three children were playing outside."Banging, jolting, up and down ... eyes were shaking. Just seemed surreal," said Blanco.Blanco says he jumped off the couch and then froze, trying to wait out the shaking."Wow, is this really happening? Just shocked ... Seemed like a good minute. Seemed like forever," said Blanco.When the home finally stopped moving, Blanco ran to his children and found them safe. A few things fell and a few cabinet doors opened, but there was no major damage. In the first few hours after the quake, he felt more than 10 aftershocks. He and his family may not get much sleep."Wondering if there's going to be more, if it's going to keep going," said Blanco.Getting back to San Diego is another concern. A crack that appeared on one of the nearby Highway 178 has been repaired, but Blanco wary of getting on the road. 1005