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WASHINGTON, May 20 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Friday approved Sutent to treat patients with progressive neuroendocrine cancerous tumors located in the pancreas that cannot be removed by surgery or that have spread to other parts of the body.Neuroendocrine tumors found in the pancreas are slow-growing and rare. It is estimated that there are fewer than 1,000 new cases in the United States each year.This is the second new approval by the FDA to treat patients with this disease. On May 5, the agency approved Afinitor."FDA believes it is important to provide cancer patients with as many treatment options as possible," said Richard Pazdur, director of the Office of Oncology Drug Products in the FDA's Center for Drug Evaluation and Research. "The agency is committed to working with companies to bring innovative new therapies to the market and encourages companies to continue exploring additional uses for approved products."The safety and effectiveness of Sutent was established in a single study of 171 patients with metastatic (late-stage) or locally advanced (disease that could not be removed with surgery) disease who received Sutent or a placebo (sugar pill). The study was designed to measure the length of time a patient lived before their disease spread or worsened (progression-free survival).Results from the study demonstrate that Sutent provided benefit to patients by prolonging the median length of time they lived without the cancer spreading or worsening to 10.2 months compared to 5.4 months for patients who received placebo.In patients treated with Sutent for neuroendocrine pancreatic tumors, the most commonly reported side effects included diarrhea, nausea, vomiting, fatigue, anorexia, high blood pressure, energy loss, stomach pain, changes in hair color, inflammation of the mouth, and a decrease in infection-fighting white blood cells.Sutent is marketed by New York City-based Pfizer.

BEIJING, Feb. 8 (Xinhuanet) -- China's railroads and highways will see their busiest day of the Spring Festival holiday on Tuesday when the number of travelers returning to major cities hits its peak, just as a cold snap sweeps across much of the country, the ministries of railways and transport said on Monday.The Ministry of Railways said on its website that there had been a sharp rise in the number of travelers leaving smaller cities on Monday bound for such places as Beijing, Shanghai and Guangzhou.The ministry said the number of people on the move on Tuesday is likely to make the day the Spring Festival travel peak.The nation's roads are also likely to be at their Spring Festival maximum on Tuesday and Wednesday, the Ministry of Transport reported on Monday on its official website.The National Meteorological Center (NMC) added on Monday that a moderate cold snap was expected on Tuesday, causing temperatures to fall by between four and six degrees in most parts of China.The weather pattern will bring widespread rain and snow to the southern part of China from Wednesday to Friday, the NMC said.The Ministry of Railways said on its website that it has asked its local branches to be prepared for the upcoming icy weather.Meanwhile, the local authorities in big cities have been bracing for the arrival of massive numbers of travelers as the Spring Festival holiday winds down.In Shanghai, tens of thousands of public transportation workers cut their holidays short and put 27 additional bus lines on the road to meet demand as passengers began arriving in large numbers at the city's railway stations.The influx began on Saturday night, according to local newspaper Wenhui Daily.On Sunday, the pressure intensified on the Qinghai-Tibet railway, two days earlier than expected.As a result, the railway company organized additional workers to facilitate the flow of people through Xining Railway Station in Northwest China's Qinghai province.Many volunteers have also been pitching in to help keep people moving and have offered to do various jobs at stations, such as helping people buy tickets and assisting them in checking their travel schedules.Among them, Liu Chen, a student from the Guangzhou-based Zhongkai University of Agriculture and Engineering, has been helping people at Guangzhou Railway Station by carrying their bags."One day, I helped more than 70 passengers with their luggage and, after all of them got on the trains, it felt like my legs were almost paralyzed," he said.The Hohhot railway bureau in North China's Inner Mongolia autonomous region said it is expecting so many extra passengers that it has scheduled four additional trains for lines to Chongqing and Beijing.With so many people scrambling to get back from family gatherings and holidays to their jobs in China's big cities, the rush to buy tickets has been phenomenal. Tickets for trains that will leave Nanjing on Tuesday for Beijing, Guangzhou, Harbin and Changchun had virtually all gone on Monday morning, Jiangsu's Yangtse Evening Post reported.On Sunday, the fourth day of Spring Festival, the country's railways carried a total of 5.3 million travelers, which was up by 12.8 percent on the 4.7 million who rode the rails a day earlier, according to the Ministry of Railways.Another 38.6 million travelers made Spring Festival trips on Sunday on buses and ships, according to the Ministry of Transport.The traditional chunyun period, or Spring Festival travel season, runs for 40 days and is calculated in two phases: 15 days before Spring Festival Eve and 25 days after it, as stipulated by the central government.China's railways moved about 77.3 million passengers during the first 15-day period, which ran from Jan 19 to Feb 2, the Ministry of Railways reported.

LOS ANGELES, April 2 (Xinhua) -- People taking antidepressants may be more likely to develop thicker arteries which may raise the risk of heart disease and stroke, a new study suggests.Depression can heighten the risk for heart disease, but the effect of antidepressant use is separate and independent from depression itself, according to the study make public by the American Association for the Advancement of Science (AAAS) on Saturday.The data suggest that antidepressants may combine with depression for a negative effect on blood vessels, said study first author Amit Shah, MD, a cardiology fellow at Emory University School of Medicine.Study findings will be presented on April 5 at the American College of Cardiology meeting in New Orleans, according to the AAAS.The study included 513 middle-aged male twins who both served in the U.S. military during the Vietnam War. Twins are genetically the same but may be different when it comes to other risk factors such as diet, smoking and exercise, so studying them is a good way to distill out the effects of genetics.Researchers measured carotid intima-media thickness - the thickness of the lining of the main arteries in the neck -- by ultrasound. Among the 59 pairs of twins where only one brother took antidepressants, the one taking the drugs tended to have higher carotid intima-media thickness (IMT), even when standard heart disease risk factors were taken into account.The effect was seen both in twins with or without a previous heart attack or stroke. A higher level of depressive symptoms was associated with higher IMT only in those taking antidepressants."One of the strongest and best-studied factors that thickens someone's arteries is age, and that happens at around 10 microns per year," Shah said. "In our study, users of antidepressants see an average 40 micron increase in IMT, so their carotid arteries are in effect four years older."Antidepressants' effects on blood vessels may come from changes in serotonin, a chemical that helps some brain cells communicate but also functions outside the brain, Shah said."I think we have to keep an open mind about the effects of antidepressants on neurochemicals like serotonin in places outside the brain, such as the vasculature. The body often compensates over time for drugs' immediate effects," Shah said. " Antidepressants have a clinical benefit that has been established, so nobody taking these medications should stop based only on these results. This isn 't the kind of study where we can know cause and effect, let alone mechanism, and we need to see whether this holds up in other population groups."

BEIJING, Feb. 16 (Xinhua) -- China's police forces have formed a nationwide computerized network to share information about fugitives, fingerprints, stolen vehicles and other crimes.Sources with the Ministry of Public Security said Wednesday that almost all police officers throughout the country have access to the network, including those in border checkpoints and exit-entry administrations.The network can verify the identification cards of Chinese citizens and help the police with anti-terrorism and anti-drug operations, a statement released by the ministry said.The Public Security Ministry is working with other government agencies such as the ministries of national security and foreign affairs, the central bank and civil aviation administration to share information from the network.

WASHINGTON, May 3 (Xinhua) -- People diagnosed with asthma in the United States grew by 4.3 million between 2001 and 2009, according to a new report released Tuesday by the Centers for Disease Control and Prevention (CDC).In 2009, nearly one in 12 Americans were diagnosed with asthma. In addition to increased diagnoses, asthma costs grew from about 53 billion U.S. dollars in 2002 to about 56 billion dollars in 2007, about a six percent increase. The explanation for the growth in asthma rates is unknown, according to the CDC.Asthma is a lifelong disease that causes wheezing, breathlessness, chest tightness, and coughing, though people with asthma can control symptoms and prevent asthma attacks by avoiding things that can set off an asthma attacks, and correctly using prescribed medicine, like inhaled corticosteroids. The report highlights the benefits of essential asthma education and services that reduce the impact of these triggers, but most often these benefits are not covered by health insurers."Despite the fact that outdoor air quality has improved, we've reduced two common asthma triggers -- secondhand smoke and smoking in general -- asthma is increasing," said Paul Garbe, chief of CDC 's Air Pollution and Respiratory Health Branch. "While we don't know the cause of the increase, our top priority is getting people to manage their symptoms better."Asthma triggers are usually environmental and can be found at school, work, home, outdoors, and elsewhere and can include tobacco smoke, mold, outdoor air pollution, and infections linked to influenza, cold-like symptoms, and other viruses.According to the report, asthma diagnoses increased among all demographic groups between 2001 and 2009, though a higher percentage of children reported having asthma than adults (9.6 percent compared to 7.7 percent in 2009). Annual asthma costs in the United States were 3,300 dollars per person with asthma from 2002 to 2007 in medical expenses. About two in five uninsured and one in nine insured people with asthma could not afford their prescription medication."Asthma is a serious, lifelong disease that unfortunately kills thousands of people each year and adds billions to our nation's health care costs," said CDC Director Thomas Frieden. "We have to do a better job educating people about managing their symptoms and how to correctly use medicines to control asthma so they can live longer more productive lives while saving health care costs."