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Researchers have found a new way to predict some aspects of mental illness, before it happens. They used artificial intelligence and more than 60 million health records. Dr. Bruce Kinon has always been fascinated by the brain. Motivated by a desire to find better treatments for mental disorders, he co-authored a study in a collaboration with Lundbeck and Kings College in London. They developed a tool that could identify early symptoms of "first episode of psychosis,” commonly referred to as when someone has a "break."“Most schizophrenia begins with the first episode of psychosis. This is a marked change in normal behavior. This is where the patient all of a sudden, rather suddenly, begins acting bizarrely, may have thoughts not based in reality,” Dr. Kinon explained. That first episode is critical, and the beginning of the lifelong disability known as schizophrenia. So, what if they could predict that first break? It's not something you can test for. “What we’ve done in this study is basically developed a population tool that one could screen populations of individuals who haven’t been identified through any health care professional as possibly having those precedence of developing a prodromal or at risk state for psychosis,” Dr. Kinon said.Dr. Kinon says there's usually some sort of stressor that leads to that break.“These periods of first psychosis seem to be preceded by what we call prodromal symptoms, a simmering, under the surface of symptoms,” he said. “Usually the individual feels out of sorts, that they don’t understand what’s going on around them. Their social relationships may be aborted."Dr. Kinon worked with IBM Watson Health Explorys Solutions. They took more than 60 million anonymized health records, including those who'd had a diagnosis of first episode of psychosis, and put them through privatization machines and let the artificial intelligence do the work. “Sometimes when you have all this data across billions of data points across thousands of patients, it becomes hard for us as humans to see the data and find patterns that’s where machine learning comes into play,” said Dr. Anil Jain, Vice President and Chief Health Information Officer at IBM Watson Health.Dr. Jain says think of it like a virtual clinical study, where you're looking for patterns. And imagine how that could one day help doctors. It took two years to get to this point, and they're not done yet. Now that there's a predictive model looking for patterns, they need to design a clinical trial so as to create an intervention. “Imagine down the road, not today, that you put this model back in the hands of clinicians who are taking care of patients that’s how you connect the dots between what we can discover from big data and real world evidence and machine learning algorithms back to the practice of medicine.”There's still a lot of questions. Would people want to know what's coming? Or the risks? Or the stigma? But for now, it's a big step, using big data, possibly leading to big medical breakthroughs. Dr. Kinon has hope for the future, and hope for prevention for those with mental illness. In the meantime, he wants people to reach out to the many organizations, like the 3221

Talk about being blindsided by an ex.The skilled Elisabeth Moss steps out of her "The Handmaid's Tale" bonnet to play Cecilia, the spunky heroine 158

Recovering drug users are using exercise to help overcome their addictions through a unique recovery program.“I love it,” Trevor Blose says. “Nothing feels better than getting out and sweating a little bit and showing yourself you can do something maybe you couldn’t do a month ago.” Blose is battling a drinking problem that cost him his freedom. “Unfortunately, because of my actions, I had to go to jail for a little bit,” he says. “There’s nothing as eye opening as seeing the person you think you are being in a place surrounded by people who you don’t think you are.”In an attempt to take control of his life, Blose now surrounds himself with other recovering addicts at The Phoenix in downtown Denver, a self-described “free sober active community,” where the only membership fee is 48 hours of continuous sobriety. “The people here saw value in me before I saw value in myself,” says Andrew Brough, manager of The Phoenix’s Denver chapter. Brough says The Phoenix has help more than 2,600 people at their chapters across the country. He says that the toughest part of this recovery program is taking that first step. “We always say that door weighs a couple thousand pounds the first time you come in here,” Brough says. “But if you can get in here and experience that first Phoenix moment for yourself, it’s going to make a world of difference.”Some healthcare specialists, however, claim exercise alone isn’t enough overcome addiction. They say though being active can help, it’s just part of very complex road to recovery. Instead, counselors advise using exercise in addition to more traditional approaches like medicine, therapy and a 12-step program.“I’d been to multiple rehabs and AA, and I tried everything and it just didn’t work for me,” says member Drew Johnson. Johnson, who has tried various recovery programs available, says exercise is the only thing that’s worked for him. “I was a hardcore opiod addict,” Johnson says. “It started off with prescription pills and then it transformed to IV heroin use.” Johnson says The Phoenix has helped him get a grip on handling addiction. He’ll be sober for one year on July 4. 2153

Stranded for hours on a snowy tarmac, passengers on an Air Canada flight were beginning to feel the stress, but their pilot knew the answer: 23 pizzas delivered to the airplane's door.Air Canada Flight 608 left Toronto bound for Halifax, Nova Scotia, on Monday night, but bad weather forced the aircraft to be diverted to Fredericton, New Brunswick. After several hours stuck in the plane, the pilot decided to order food.Jofee Larivée, the manager at Minglers Restaurant and Pub in Oromocto, received the pilot's call and took down his order for 23 pizzas topped with cheese and pepperoni."We told him we could have them made in an hour or hour and a half," Larivée said.She said they have never delivered pizza to an airplane, and they were "laughing all night" about the unusual order.Her crew got the pizzas ready in an hour and sent them to the airport via Minglers' delivery service.Larivée said she called the plane to tell the pilot of the pizzas' arrival and the captain sent people to meet the delivery at the door.Passenger Philomena Hughes told 1069

Sen. Rand Paul defended why he opted to not self-quarantine while awaiting for the results from a COVID-19 test he took last week. On Sunday, Paul's office announced that the the U.S. senator from Kentucky tested positive for coronavirus. Paul's office said he was asymptomatic and feeling fine. Paul continued to work on Capitol Hill until he learned of his positive test.Although Paul was not around many staffers, he was in close proximity of a number of fellow senators. Republican senators Mitt Romney and Mike Lee opted to self-quarantine following Paul's announcement. Paul's office said that staffers began working remotely 10 days ago and he had virtually no direct contact with his staff. “Given that my wife and I had traveled extensively during the weeks prior to COVID-19 social distancing practices, and that I am at a higher risk for serious complications from the virus due to having part of my lung removed seven months ago, I took a COVID-19 test when I arrived in D.C. last Monday," Paul said in a statement. "I felt that it was highly unlikely that I was positive since I have had no symptoms of the illness, nor have I had contact with anyone who has either tested positive for the virus or been sick."The CDC issued the following guidelines for testing:Hospitalized patients who have signs and symptoms compatible with COVID-19 in order to inform decisions related to infection control.Other symptomatic individuals such as, older adults (age ≥ 65 years) and individuals with chronic medical conditions and/or an immunocompromised state that may put them at higher risk for poor outcomes (e.g., diabetes, heart disease, receiving immunosuppressive medications, chronic lung disease, chronic kidney disease).Any persons including healthcare personnel, who within 14 days of symptom onset had close contact with a suspect or laboratory-confirmed4 COVID-19 patient, or who have a history of travel from affected geographic areas5 (see below) within 14 days of their symptom onset.Paul believed he should have been tested because of a preexisting condition."The nature of COVID-19 put me – and us all – in a Catch-22 situation," Paul said. "I didn’t fit the criteria for testing or quarantine. I had no symptoms and no specific encounter with a COVID-19 positive person. I had, however, traveled extensively in the U.S. and was required to continue doing so to vote in the Senate. That, together with the fact that I have a compromised lung, led me to seek testing. Despite my positive test result, I remain asymptomatic for COVID-19."Although Paul was the first senator with a confirmed positive test, two members of the House confirmed positive coronavirus cases last week. 2706