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WASHINGTON, Dec. 12 (Xinhua) -- British scientists have discovered a new way to target cancer through manipulating a master switch responsible for cancer cell growth. The findings, published Monday in the U.S. journal Cancer Cell, reveal how cancer cells grow faster by producing their own blood vessels.Cancer cells gain the nutrients they need by producing proteins that make blood vessels grow, helping deliver oxygen and sugars to the tumor. These proteins are vascular growth factors like VEGF -- the target for the anti-cancer drug Avastin. Making these proteins requires the slotting together of different parts of genes, a process called splicing.Scientists at the University of West England and the University of Bristol discovered that mutations in one specific cancer gene can control how splicing is balanced, allowing a master switch in the cell to be turned on. This master switch of splicing makes cancer cells grow faster, and blood vessels to grow more quickly, as they alter how VEGFs are put together.In experimental models, the researchers found that by using new drugs that block this master switch they prevented blood vessel growth and stopped the growth of cancers."The research clearly demonstrates that it may be possible to block tumor growth by targeting and manipulating alternative splicing in patients, adding to the increasingly wide armory of potential anti-cancer therapies," the authors said.
BEIJING, Oct. 27 (Xinhuanet) -- A new study shows that it's not simply a lack of willpower that explains weight regain but hormones keep one insisting on eating, a persistent biological urge. As any dieter knows, it's hard to keep weight off. Weight regain is a familiar problem for dieters. The research appears in Thursday's issue of the New England Journal of Medicine. To study what drives it, Proietto and his colleagues enrolled 50 overweight or obese patients in Australia in a 10-week diet program. On average, the participants lost almost 30 pounds in the 10 weeks - faster than the standard advice of losing a pound or two per week. Even so, they gained an average of 12 pounds back over the next year. The scientists checked the blood levels of nine hormones known to influence appetite - and found that even a year after the end of the weight-loss program, six of the hormones were still out of whack. People who regain weight should not be harsh on themselves, as eating is our most basic instinct, study author Joseph Proietto of the University of Melbourne in Australia said. It's better not to gain weight than to try to lose it.
MOSCOW, Oct. 24 (Xinhua) -- The Russian Space Agency Roscosmos confirmed on Monday the list of next crew members who will fly to the International Space Station (ISS) on Nov. 14.Russia's Soyuz TMA-22 spacecraft will bring Russian cosmonauts Anton Shkaplerov and Anatoly Ivanishin and American astronaut Daniel Burbank to the ISS for a 124-day-long mission.Russia's Gennady Padalka and Sergei Revin and American Josef Akaba are announced as the backup crew.According to the Roscosmos, the new crew will host one manned and three unmanned cargo ships during their stay in the ISS and conduct a space walk as well as 37 scientific experiments.During the new crew's stay, the ISS would also make its 75,000th revolution around the Earth, the Roscosmos said.The launch of the Soyuz TMA-22 was initially scheduled on Sept. 22, but was postponed after the failed launch of the Progress cargo ship to the ISS on Aug. 24.
BEIJING, Jan. 12 (Xinhua) -- China's consumer price index (CPI), a main gauge of inflation, rose 4.1 percent year-on-year in December, down 0.1 percentage point from November on falling non-food prices, the National Bureau of Statistics (NBS) said Thursday.The CPI was up 5.4 percent in 2011 from the previous year, well above the government's full-year inflation control target of 4 percent, the NBS said in a statement on its website.The inflation rate in December marked a five-straight-month decline after hitting a 37-month high of 6.5 percent in July amid government tightening measures, according to the NBS data.On a monthly basis, the cost of living dipped 0.2 percent in December, while prices of entertainment, educational and cultural articles and services dropped 0.3 percent, the NBS said.Food prices, which account for nearly one third of the basket of goods in the nation's CPI calculation, went up 9.1 percent year-on-year in December and 1.2 percent month-on-month, the NBS said.The December inflation figure was in line with the market expectation, as many economists forecast that the CPI would grow around 4 percent year-on-year in December.China's Producer Price Index (PPI), a major measure of inflation at the wholesale level, rose 1.7 percent in December year-on-year, further weakening from 2.7 a month earlier.China has made controlling prices a top priority last year and implemented a series of measures to address the issue, including tightening monetary policy, cracking down on speculation, increasing food supplies and reducing circulation costs.
BEIJING, Oct. 14 (Xinhuanet) -- Materialism could be harmful to marriage, according to a new study published in the American Journal of Couple & Relationship Therapy Thursday.The researchers collected online "relationship assessment" questionnaires from 1,734 U.S. married couples.The questionnaire covered the topics about the couples' marital satisfaction, conflict patterns, marital communication, and marriage stability, and so on.Non-materialistic couples were about 10 to 15 percent better than those materialistics in their marital satisfaction, marriage stability and conflict levels, according to the study."What we found was a general pattern that materialism seems to be harmful to marriage," said study researcher Jason Carroll, a professor of family life at Brigham Young University.It didn't matter whether the materialistic spouse was the man or the woman, he added.However, materialism is not simply black-or-white: some couples can pursue their fortune and keep their relationship strong at the same time, the researcher suggested.But breaking their materialistic thought would be helpful for most couples, Carroll concluded.