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Excessively high or low body mass index measurements have been linked to an increased risk of dying from nearly every major cause except transport accidents, new research says.The?study, published Wednesday in The Lancet Diabetes and Endocrinology and conducted by scientists at London School of Hygiene and Tropical Medicine, revealed that BMI that's either too high or too low is tied to increased morbidity from a range of major diseases.Krishnan Bhaskaran, lead author of the study and associate professor of statistical epidemiology, noted that his team found "important associations" between BMI and most causes of death."BMI is a key indicator of health. We know that BMI is linked to the risk of dying overall, but surprisingly little research has been conducted on the links to deaths from specific causes," he said."We have filled this knowledge gap to help researchers, patients and doctors better understand how underweight and excess weight might be associated with diseases such as cancer, respiratory disease and liver disease."BMI is determined by dividing a person's weight in kilograms by the square of their height in meters.The study authors say they discovered that maintaining a BMI in the range of 21 to 25 kg/m2 is linked to the lowest level of morbidity.BMI outside this range was shown to have a "J-shaped association" with nearly all causes of death, not solely the most prevalent diseases. This means BMIs both lower and higher than the optimal range lead to increased risk of morbidity.The study, which analyzed data from 3.6 million people and 367,512 deaths, showed that obesity, or BMI of 30 or more, was linked to an increased prevalence of two major causes of death: heart disease and cancer."BMI higher than 25, the upper end of healthy, is linked to most cancers, most cardiovascular diseases, respiratory disease, and liver and kidney conditions," Bhaskaran said.Obesity was shown to reduce life expectancy by 4.2 years in men and 3.5 years in women, and it can contribute to other chronic conditions including respiratory disease, liver disease and diabetes.The British Journal of Cancer reported in April that obesity is linked to 7.5% of cancers in UK women.The charity Cancer Research UK estimated that 23,000 women will deal with obesity-related cancers by 2035. Obesity will also become the most common cause of cancer in women by 2043 if trends continue.The study also revealed that being underweight is linked to a "surprising wide range of deaths," including dementia, Alzheimer's, cardiovascular disease and suicide.However, Bhaskaran noted that links between low BMI and causes of death were more "observative," as it was less clear whether low weight was the direct cause of illness or rather a marker of poor health more generally.He also acknowledged the limitations of the study, which included a lack of information on the diet or level of physical activity of the individuals involved and the impact these factors may have had on morbidity.He nevertheless noted that the findings reiterated the importance of maintaining a BMI within the 21 to 25 range. 3130

Estée Lauder announced significant changes as it looks to recover financially from the coronavirus pandemic.On Thursday, the company announced they were closing between 10-15% of its freestanding stores and lay off 1,500-2,000 employees, about 3% of the workforce.A list of the stores closing has not been announced.The cosmetic giant said the pandemic had affected the bottom line; therefore, they were announcing a 2-year plan called the Post-COVID Business Acceleration Program to adjust its investments.The plan will go into effect in the first quarter of next year. "Our strategic priorities for fiscal 2021 rightly balance investment in these engines with cost discipline amid the ongoing pandemic," Fabrizio Freda, President, and Chief Executive Officer said in the press release. "Through the Post-COVID Business Acceleration Program announced today, we are better aligning our brick-and-mortar footprint to improve productivity and invest for growth. We are well-positioned to drive growth as the market dynamics support it, yet remain equally mindful of the effects of COVID-19 on consumers, the retail sector and economics, in general, as well as geopolitical uncertainty."The company added they would focus on digital capabilities, advertising, and promotions.The company said the plan is expected to save the company, before taxes, about 0 million to 0 million. 1388

ESCONDIDO, Calif. (KGTV) – Police in Escondido have identified the suspect shot and killed by an officer at Valley View Casino Saturday night as Osbaldo Ramirez Jimenez, 50.The incident began after police received a domestic disturbance call on the 1400 block of Timber Glen Road in Escondido.When they arrived, police say the suspect got into a vehicle and led them on a chase that ended at the casino’s valet entrance.RELATED: Officer-involved shooting reported at Valley View Casino in North San Diego County?When Jimenez got out of the vehicle, police say they noticed he was holding a handgun when the officer-involved shooting took place. Jimenez was taken to the hospital where he later died. Authorities also identified the officer involved in the shooting as Officer Terrence Pizzuti, who they say has been with the department since 2013.The incident reportedly caused chaos inside the casino. One woman inside at the time of the shooting was trampled. She was taken to the hospital where she is expected to survive.The San Diego Sheriff’s Department is leading the investigation. When the department is finished, the investigation will be handed over to the District Attorney’s office for review.Anyone with information on the shooting is asked to call the Sheriff’s homicide unit at 858-974-2321.Video of the aftermath of the shooting was captured on social media:  1399

ESCONDIDO, Calif. (KGTV) — A Vietnam veteran who is struggling with memory issues says a "mistake" could cause him to be evicted from his Escondido apartment.Orrin Donohoe's studio apartment in the Adult Village complex isn't spacious, but it is home. For how long?"I'm scared of what's going to happen to me," said Donohoe.Donohoe, who served as a deckhand for three years on the USS Columbus CG-12 during the Vietnam War, was later diagnosed with PTSD. "Constantly stressed, afraid I'm going to forget something," said Donohoe.Problems with short-term memory steadily grew worse."Missing doctor's appointments, missed bills, forgetting to get gas, forgetting to check the mail. Goes on and on," said Donohoe.The memory issues that cost him so many jobs could now cost him his home. Donohoe depends on Section 8 housing vouchers to pay most of his rent. A few days ago, Donohoe got a letter from his landlord: A three-day notice to pay his overdue rent.Donohoe believes he forgot to fill out the paperwork for the annual renewal for his housing voucher."Scared and depressed," said Donohoe.He owes more than 0 for this month's rent."I don't have it. I have a 0 in the bank and I haven't paid my electric yet," said Donohoe. Donohoe thinks he could be evicted at any moment. He says the County Housing Authority told him he could reapply for a voucher in six months. Until then, he'll likely have to live on the streets."No sense of security ... I'm frightened," said Donohoe.The County Housing Authority is reviewing the case but declined to talk specifics, citing confidentiality.A Gofundme campaign has been set up to help raise funds for Donohoe. 1664

ENCINITAS, Calif., (KGTV) -- Friends and family celebrated the survival of 14-year-old Keane Webre-Hayes at a community paddle-out event. The teenager was attacked by a great white shark at Beacon's Beach one year ago this month. The line between life and death is so thin for Keane."People come up to me and say, 'hey what's that from'?" Keane said as he pointed at the large scars on this left cheek, ear, and neck. Last September, the then 13-year-old was bitten by a great white shark while lobster diving at Beacon's Beach. "I swam 70 yards to a kayak with basically no arm," Keane said. He screamed for help toward a few kayakers in the distance. That is when he met Matthew Ephron, who helped him get to shore. "He did most of the work, and we just got him in so that he wouldn't be out there forever," Ephron said. Doctors said Keane lost half of the blood in his body. But 1,000 stitches later, the boy survived. And for the last year, doctors, trainers, therapists, and teachers helped Keane find his new normal."We honestly couldn't have gone through it without the support of the community," Keane's mother, Ellie Hayes, said. "The hugs, the love, the gifts, the support."So to say thank you, Keane's family hosted a paddle-out at Moon Light State Beach to honor his survival. "Without them, I would not be able to move my arm," Keane said. "I probably would not be who I am today without them."Keane has made incredible strides. From being bedridden for weeks, he now plays in a club beach volleyball team. Family and friends said Saturday's paddle-out is a celebration of life and proof of Keane's incredible resilience. "I definitely want people to know that I can do things, and also if I can do that, you can do that if you put your mind to it," Keane said. Local surf-art legend Andy Davis also attended the event and gave Keane a custom painting featuring a man on a surfboard in Keane's favorite color, pink. 1937