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SAN DIEGO (KGTV) — UC San Diego researchers are testing a technology that's been in development for more than a decade to fight the coronavirus.In lab experiments, "nanosponges" covered in human lung cell membranes and immune cell membranes were found to attract and neutralize the SARS-CoV-2 virus in cell culture, according to a UCSD release. This caused the virus to lose about 90% of infectivity, or its ability to hijack cells and reproduce.The tiny sponges are designed to impersonate and protect healthy cells by soaking up harmful pathogens and toxins, according to Liangfang Zhang, a nanoengineering professor at the UC San Diego Jacobs School of Engineering. RELATED: San Diego company's COVID-19 test gets emergency approvalFor example, the nanoparticle covered in membranes from cell types the virus is known to invade latch on to the virus. This prevent the virus from then entering an actual human cell."Traditionally, drug developers for infectious diseases dive deep on the details of the pathogen in order to find druggable targets. Our approach is different. We only need to know what the target cells are. And then we aim to protect the targets by creating biomimetic decoys," said Zhang.While Zhang has spent the last 10 years developing the technology, his lab turned to using the nano-particle to fight the coronavirus when the pandemic hit.RELATED: Scripps Research's antibodies study shows signs of success against coronavirusNow, the first data on the technology's ability to battle the virus is being released after testing by researchers at Boston University."Another interesting aspect of our approach is that even as SARS-CoV-2 mutates, as long as the virus can still invade the cells we are mimicking, our nanosponge approach should still work. I’m not sure this can be said for some of the vaccines and therapeutics that are currently being developed," said Zhang.UCSD researchers will test the nanosponges’ effectiveness in animal models in the next few months and are moving as fast as possible to eventually test the technology in humans. RELATED: Startup creates mobile COVID-19 testing clinic on wheelsNanosponges have a massive amount of testing ahead before they make it to human tests, Zhang said."I see potential for a preventive treatment, for a therapeutic that could be given early because once the nanosponges get in the lung, they can stay in the lung for some time," Zhang said. "If a virus comes, it could be blocked if there are nanosponges waiting for it."(Read more about the study and nanosponges here.) 2562
SAN DIEGO (KGTV) -- Two people spotted by police smashing a window at a Pacific Beach Wendy’s restaurant were arrested after leading officers on a chase.The incident unfolded at around 1:15 a.m. at the fast food restaurant on 1621 Grand Ave., according to San Diego police.Officers were in the area when they saw two people smash a window at the eatery. When police tried to make contact with them, they got into a pickup truck and drove away.The truck reached speeds of up to 100 MPH as it led police on a pursuit towards Interstate 8.Police’s ABLE helicopter helped ground units track the truck into the Midway District, and as the vehicle tried to make a left turn on Rosecrans Street, it crashed into the center divider.The truck then entered a nearby strip mall and came to a stop. The two occupants got out, but officers arrived and took them into custody.Police are trying to determine if the window smash was part of a burglary attempt or an act of vandalism. 975
SAN DIEGO (KGTV) – Trips to the grocery store can be tough on the wallets of families trying to make it in San Diego.According to the USDA, a family of four can spend anywhere between 0 and ,300 a month on groceries alone. The bigger the family, the more you spend. San Marcos resident Melanie Anderson says the grocery bill for her family of six was around ,500 a month.“I went to the store with no plan. I would go there and let the store tell me what I needed,” Anderson said.RELATED: USDA's meal planning guide for stretching your food budgetAnderson, a stay-at-home mom of four children, said she and her husband were interested in traveling more so they decided to take a look at their budget.“I realized I wanted to save money so that I could spend it on unforgettable things,” Anderson said.Once all the numbers were in place, they realized they could make changes to their grocery bill.RELATED: Ocean Beach duo cook up 'foodie' meals on a day budget“We were wasting food, we were throwing away food, we weren't planning,” said Anderson.Now the family spends between 0 and 0 a month on groceries.Anderson says her strategy is 'meal planning in reverse'. She focuses on creating dishes around the food she already has and only buying meat, bread, and produce that are marked down or on clearance.One of her biggest tips is calling the grocery stores in advance.RELATED: How to budget when you're on an inconsistent income“First, call the grocery store and ask them what time do you clearance whatever item you’re looking for. Whether it’s the meat department, ask to speak to the meat department. If you’re specifically looking for organic produce, ask that. They are very agreeable in letting you know that information.” Anderson said. According to Anderson, the system is faster than her old trips to the store. “I blaze in there, I look at the produce, I look at the deli meat, I look at the regular meat, the bakery items and I am out of there in ten minutes,” Anderson said. RELATED: San Diego woman climbs out of 3,000 debt holeSome of the items in her fridge include organic mushrooms, usually .99, marked down to .49. The lettuce she bought marked at .49, cases of wine for less than , ground turkey for .99 and ham on clearance for .99. Anderson is now a budget-savvy blogger and documents her grocery store savings and other ways to cut down your budget on her website and Facebook page, Six On A Budget. Her followers are now posting their grocery store victories. “They send me pictures of everything in their grocery cart. They’ll say I used to spend 0, now I spend 0. It’s so satisfying,” Anderson said. RELATED: San Diego ShortFall tool: Can you make ends meet?Anderson suggests heading to the grocery store early to get the best deals. She also says you should double check the 'sell by', 'use by', and 'best by' dates because you usually have a few days to use certain items before they go bad. Anderson also recommend you get creative in the kitchen with sites like Supercook where you can plug in ingredients you already have for recipe ideas.If you prefer to create a shopping list before you head to the store, the USDA has budgeting tips and suggested menus to help you save money. 3340
SAN DIEGO (KGTV) - With growing freelance and telecommuting opportunities, more San Diegans are working from home. There are a few workflow goals to keep in mind as you step back from the office. Get dressed. This must-do is not an option for traditional office workers, who don’t have the luxury of typing reports in their pajamas. Putting on a new outfit for your day, even if it’s just jeans, can get you in the right frame of mind to start your day. Set work hours. It may be tempting to start late on days that you’re tired or busy. Maintain a distance between your work and personal lives by setting firm hours. Establish your space. If you don’t have a proper home office, this may be the time to invest in a quality chair and desk. By doing work away from the dining table, you’ll create emotional distance when it’s time to call it a day. RELATED: Co-working office spaces helping business owners thrive in San DiegoStay organized. To-do lists can help you stay on top of your workload. You’ll also want to keep track of clients or contacts. There are multiple apps to help you no matter what your job or project. Schedule friends and family. Does your mother-in-law love to drop in? Give her a window of time when it’s acceptable to stop by. The same rule applies to children who will be home when you’re working. Ditch the kitchen. When it’s time for a break, don’t automatically reach for a snack. Keep water and coffee nearby so you’re not tempted to open the fridge.RELATED: Making It in San Diego: How to convince your employer to let you telecommute 1573
SAN DIEGO (KGTV)- A group of ten college girls rode their bikes from Seattle to San Diego to fight sex trafficking. The group is comprised of women from Texas, Arkansas, Oklahoma and Alabama.Beginning in Seattle and ending in San Diego, these first-time riders biked down the West Coast, meeting with communities and local leaders along the way to spark conversations and raise money for the long-term, rehabilitative care for children rescued from sex traffickers.This is the third year for Pedal the Pacific and this year they nearly doubled their financial goal. They ended up raising over 250 thousand dollars. The organization tells 10News, "The team just received a 0,000 donation from the Harry W. Bass Jr Foundation. The foundation says they were appalled by Jeffrey Epstein’s alleged crimes, but they found a positive way to make a difference with their donation to Pedal the Pacific."All of the money raised will be donated to The Refuge Ranch, the largest long-term, live-in rehabilitation facility for child survivors of sex trafficking in the US. 1071