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Maryland-based vaccine developer, Novavax, has received .6 billion from the federal government to complete late-stage clinical development; set up large-scale manufacturing; and deliver 100 million doses of NVX?CoV2373, its COVID-19 vaccine candidate, as early as late 2020.This is the largest vaccine deal to date with the Trump administration as part of their Operation Warp Speed, which is focused on making a COVID-19 vaccine and treatments available as quickly as possible.Novavax has not brought any of their developed vaccines to market. According to information on their website, they have developed several vaccines for infectious diseases, however they are all in various stages of development or clinical trials. These include vaccines for the seasonal flu and RSV. Other vaccines created by Novavax are not actively being developed or studied at this time, including ones for Ebola, MERS, and SARS.According to a statement from Novavax, the agreement with the federal government includes the company demonstrating being able to rapidly get manufacturing and large-scale production of the vaccine going once approved. Novavax hopes to conduct their late-stage clinical study with 30,000 subjects in fall 2020.An early-stage clinical study took place in Australia in May on 130 participants. Study results are expected at the end of July.“Today’s .6 billion investment supports the Novavax candidate, depending on success in clinical trials, all the way through to manufacturing 100 million doses for the American people,” said U.S. Health and Human Services Secretary Alex Azar.Regeneron Pharmaceuticals has also received 0 million through Operation Warp Speed on Tuesday, to make and supply its COVID-19 vaccine candidate, REGN-COV2. Their vaccine is currently in phase 2 and phase 3 clinical studies for the treatment and prevention of COVID-19.Regeneron has several vaccines on the market currently, including Dupixent, used to treat allergic diseases such as eczema, asthma and nasal polyps which result in chronic sinusitis, and Praluent, used to treat high cholesterol. 2101

Mayor Bottoms & Interim Chief Bryant speak on 8-year-old murdered over the holiday weekend. https://t.co/iCjls5QC47— Atlanta Police Department (@Atlanta_Police) July 5, 2020 185

Mail delivery is something just about everyone depends on, but for millions of Americans, mail services are a vital lifeline for health.“Levothyroxine which is a thyroid medication, I've taken this probably 40 years,” 87-year-old Barbara Raizen said. She takes multiple medications. “I right now live in a senior residence, I live in independent living.”She relies on the Postal Service for a lot of reasons, one being her medications.“It’s cheaper, it’s cheaper than the drug store, it’s cheaper than King Soopers,” she said. “And you know, every dollar counts.”That and it’s difficult for her to leave, due to COVID-19 restrictions. “If we go out we have to come back and be quarantined for two weeks,” Raizen said.Millions share similar concerns as the U.S. Postal Service deals with increased demand, lower processing capacity, and potential cost cutting.“It’s really a problem,” Raizen said. “If the prescription runs out, I have to call the doctor and he calls it back in but it comes by mail and it takes 7 to 10 days or more to get it.”“It’s both the increase in volume and the decrease in the processing capacity,” said Jeannette Song, an operations management expert and Duke University professor. “Many more people ordered online, so that increased the volume for the postal services.”The National Association of Letter Carriers said the Postal Service handles 1.2 billion prescription drug shipments a year, nearly 4 million every day. Data from the Kaiser Family Foundation estimates 14 million people relied on mail order pharmacies for at least one prescription in 2018.“At each step, the process has its capacity,” Song said. “It’s multistage processing, so this is a journey of that. Certainly each step takes some time.”While USPS is experiencing strains right now, she said this happens other times, too.“Holidays,” she said. “Usually get delays, it’s just the same thing”With all the debates going on over cost cutting and the current pressures on the Postal Service, millions are worried. Some taking to Twitter to share their story under the #USPSMeds hashtag.“The post office is important,” Sandy Reavey said. She also relies on the Postal Service for her medications. “It’s just easier. You don't have to go and stand in line at the pharmacy, and it can be cheaper because you can get a three month supply versus doing it every month and having to go back every month to the pharmacy.” She added that especially right now, not everyone necessarily wants to stand in a line with a bunch of people.She receives multiple medications through the mail. “If I don’t take the medication, it causes my heart to go out of whack and could cause me to have a heart attack or a stroke.”As debates continue over Postal Service overtime and other cost cutting measures, Postmaster General Louis DeJoy has promised to suspend for now. Sandy and Barbara continue hoping their medications make it on time.“Growing up I’ve already trusted their mail service to deliver and not tamper with my mail,” Reavey said.“What are you supposed to do? Can’t do everything online,” Raizen said. 3096

MIAMI SHORES, Fla. (AP) — Authorities say a Florida police officer’s wife died after becoming trapped in the back of his patrol vehicle for several hours during a hot afternoon. Investigators are treating the death of 56-year-old Clara Paulino as an accident. She died Friday afternoon while her 58-year-old husband Aristides Paulino was sleeping in their Miami Shores home after finishing a midnight shift. The Miami Herald reports Paulino woke up around 5 p.m. and started looking for his wife, finding her cell phone on the back patio. He and one of his sons found Clara in the vehicle. Officials say she had climbed into the backseat of his marked SUV to find something when the doors somehow closed, and a self-locking mechanism engaged. The vehicle has a partition between the back seat and front seat, meaning Clara could not reach the horn. “It’s literally a cage,” one Miami police officer familiar with the vehicle told the Miami Herald.Temperatures reached over 90 degrees as she spent about four hours in the vehicle. 1037

Many animal shelters are worried the economic impact of the COVID-19 pandemic will cause a surge in pet surrenders, a stark contrast from when shelters saw record fostering and adoption rates four months ago."What we've seen since then is that the number of total dogs and cats that have come into shelters and rescues across the country has continued to decrease compared to the levels of 2019. So, fostering has stayed high but we just have fewer animals that we’re trying to get into foster care than the shelters had to last year," says Lindsay Hamrick with the Humane Society of the United States.Hamrick says animal control centers that shut down during the start of the pandemic are now back up and operating, but are still being selective about which animals need to be picked up."Intakes are still about 40% down compared to 2019 for both cats and dogs," says Hamrick.Valley Oak SPCA in Visalia, California, saw a record number of adoptions in June, nearly double what they had last year. But executive director Lydia House says they're concerned about the impact the economy will have in the coming months."We had a couple surrenders that said, 'I haven’t been able to feed my dog in three days. I have no money. I’m being evicted.' We did have some senior citizens who wanted to surrender their pets because they were afraid they were going to get [COVID-19] and not be able to take care of their pets," says House.The Humane Society of the United States has been closely following states that are lifting their eviction moratoriums as those states may see a boost in pet surrenders and strays."Surrenders that are related to evictions to not having enough money to be able to afford veterinary care - all of the pieces that come along with an economic downturn," says Hamrick.Overall, many shelters report with so many people working from home, adoptions and fostering of animals are still high. So the Humane Society of the United States is now urging animal lovers to think beyond shelter animals and focus on a neighbor or friend who may be going through a tough time."When someone loses their house or apartment, it's going to take months or even a year to find pet friendly housing again. So we’re really doing a push that people who are interested in fostering and had a good experience during the pandemic with taking care of other pets, to consider doing that for your neighbors. That way, possibly in the future, there can be a reunification of the pet with the family that they were separated from because of the economic issues," says Hamrick.Right now, more than half of states nationwide have lifted their eviction moratoriums. The Humane Society of the United States recommends supporting your local animal shelters as much as possible during this time to help get them and the animals through any economic hardship. 2850