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WASHINGTON, April 25 (Xinhua) -- A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.Working in cell lines from colorectal cancer patients, researchers found that the class of drugs called PARP inhibitors worked against tumors with mutations in the MRE11 gene.About 15 percent of all colorectal cancers have what's called microsatellite instability, a type of error in the DNA. About 82 percent of those tumors have the MRE11 gene mutation."This is a potential broader application for PARP inhibitors, beyond breast and ovarian cancer. This is a class of drug that's already shown safety in early clinical trials and now might benefit some colorectal cancer patients as well," says lead study author Eduardo Vilar-Sanchez, a hematology/oncology fellow at the university, in a statement.The study, which was published Monday in Cancer Research, also found that PARP inhibitors are even more effective when both copies of MRE11 were mutated. Each person carries two copies of each gene, which means mutations can occur in either one or both copies. The researchers suggest that PARP inhibitors could be targeted specifically to colorectal cancer patients who have two copies of the mutated gene.Researchers are planning a phase I clinical trial to look at using PARP inhibitors in colorectal cancer patients with two mutated copies of MRE11. Future trials are being considered using PARP inhibitors to prevent colorectal cancer and other cancers in people with Lynch syndrome whose tumors have this mutation.Microsatellite instability is also seen in prostate cancer and endometrial cancer, suggesting potential for PARP inhibitors to play a role in additional types of cancer as well, Vilar-Sanchez says, adding that more research is needed in these areas.

WASHINGTON, April 25 (Xinhua) -- The U.S. National Aeronautics and Space Administration (NASA) and the U.S. Agency for International Development (USAID) have agreed to expand their joint efforts to overcome international development challenges such as food security, climate change, and energy and environmental management.NASA Administrator Charles Bolden and USAID Administrator Rajiv Shah signed a five-year memorandum of understanding on Monday, at NASA Headquarters. The agreement formalizes ongoing agency collaborations that use Earth science data to address developmental challenges, and to assist in disaster mitigation and humanitarian responses. The agreement also encourages NASA and USAID to apply geospatial technologies to solve development challenges affecting the United States and developing countries."Technologies for NASA missions have long improved life here on Earth. Together with USAID, we'll meet even more sustainable development challenges here on the ground, solving problems for the world community," Bolden said in a statement. "As we explore space, we'll also be exploring solutions to important health, nutritional and safety challenges in developing countries."The agencies will continue collaborations to stimulate innovative science and technology solutions to international development challenges by using Earth science data, research results, computer models, visualization applications and remote- sensing techniques.USAID is the lead federal development agency implementing U.S. development efforts through field-based programs and projects around the world. NASA has broad experience with Earth science research, development of Earth science information products, and technology applications."Through our partnership with NASA, we can apply the latest, cutting-edge technology to deliver meaningful results for people in developing countries in areas like health, food security and water," Shah said. "It's a prime example of our efforts to use the power of science and technology to tackle today's pressing development challenges."Since 2003, NASA and USAID have worked together building and expanding the SERVIR program, which allows people in developing regions to use Earth observations for addressing challenges in agriculture, biodiversity conservation, climate change, disaster response, weather forecasting, and energy and health issues.The agencies also collaborate on the LAUNCH program, which supports science and technology innovators in the nonprofit and private sectors. The program's goal is improving innovations to achieve greater impact on sustainability issues.

SAN FRANCISCO, March 29 (Xinhua) -- Amazon.com Inc. on Tuesday announced the launch of an on-line music storage service,which enables users to store digital music in the cloud and access it from computers and devices running Google's Android operating system.The new service, called "Cloud Drive," offered customers five gigabytes of free storage on Amazon Web servers for all kinds of digital files, including music, photos, videos and documents. For paid plans, users can purchase storage space starting at 20 U.S. dollars a year for 20 gigabytes.The on-line retailer also launched "Cloud Player for Web" and " Cloud Player for Android." The former allows users to get the media files they stored on Amazon's servers from a Web browser on a Mac or PC. The latter lets users play music they have uploaded on Cloud Drive, computers or a smartphone that runs Android operating system.Analysts said Amazon is stepping up its rivalries with Apple and Google. Both companies are also working on similar services, allowing users to store their music on-line and access it from any compatible device.Media reports said that Apple was pushing hard to launch a digital music locker service in April. Google was also reported to be testing its own digital locker service but it still needs to make agreements with major music labels.

BEIJING, March 18 (Xinhuanet) --In February this year, Chinese National Geographic magazine published a series of exquisite pictures about Shicheng City (literally, Lion City), and since then, the public's strong interest in the city has been aroused again.The city of nearly 1,339 years of age, situated in east China's Zhejiang Province, has been submerged under Qiandao Lake since 1959 for the construction of the Xin'an River Hydropower Station.International archeologists vividly named the city submerged in water "time capsule." Since it is shielded from the erosion by wind, rain and sun, a city submerged in water comparatively maintains a stable condition, thus making the city a virtual time vessel. Seen from the pictures of Shicheng City, stairs in ancient houses, walls and memorial arches remain the same as they were thousands of years ago.Shicheng City was named after the Wu Shi Mountain (literally, Five Lion Mountain) in the northern part of Sui'an County, Zhejiang. It was once the center of politics, economics and culture of Sui'an County in that area.As written in the "History of Sui'an County," there are all together 265 arches submerged under Qiandao Lake, among which the Jie Xiao Memorial Arch's fine carvings remain well-preserved.According to the restored map of Shicheng, there were five city gates in all directions. You can find one city gate tower on each city gate and all together there are five towers. Besides, six streets in Shicheng City were used to connect every corner of the city as a whole. The typical roads in Shicheng City were stone roads, tidily paved by flagstone and pebbles.

MOSCOW, Jan. 24 (Xinhua) -- Russian President Dmitry Medvedev and visiting Chinese State Councilor Dai Bingguo held talks here on Monday, discussing prospects for the development of cooperation between the two countries.Medvedev and Dai Bingguo discussed the development of Russian- Chinese bilateral cooperation and interaction on the international arena.The Russian president said the Sino-Russian strategic partnership of coordination is developing further in all aspects, as the leaders of the two nations kept close contact during last year and cooperation in the economic and trade sphere has been deepened.Russia sees China as its closest partner, a position that will never be changed, Medvedev stressed.Russia is willing to work together with China to promote all- around cooperation and coordination on international and regional issues, Medvedev said.He said the strategic security talks between Russia and China, a major goal of Dai's current visit, have served as an important channel for bilateral coordination and exchanges, and played a pivotal role in enhancing bilateral strategic mutual trust.Dai Bingguo, who arrived in Moscow Sunday for a three-day visit, said that the first ten years of the 21st century had been important for Sino-Russian relations.China attaches great importance to the strategic coordination with Russia and is willing to work with Russia to develop their strategic partnership of coordination at a higher stage, the Chinese state councilor said.