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The Food and Drug Administration approved on Wednesday a treatment for the Ebola virus. This is the first FDA-approved treatment for Zaire ebolavirus infection in adults and kids.Zaire ebolavirus is one of four Ebola virus species that can cause potentially deadly infections. It is transmitted through direct contact with blood, tissue or body fluids of an infected person or wild animal.The treatment, Inmazeb, is a mixture of three monoclonal antibodies and was created by Regeneron Pharmaceuticals. The three antibodies work together to bind to the glycoprotein on the surface of the Ebola virus and block it from entry into the body’s cells.Inmazeb was tested in the Democratic Republic of the Congo during an Ebola virus outbreak in 2018-2019 through a partnership between the local government and the National Institutes of Health.A vaccine for Ebola virus was approved by the FDA in December 2019.Regeneron is also the company behind an experimental antibody cocktail that was given to President Donald Trump following his diagnosis of COVID-19, and which he said “cured” him. Trump was also prescribed the antiviral drug remdesivir and the steroid dexamethasone at the time.Regeneron’s COVID-19 treatment is a mix of two powerful antibodies that are believed to boost the immune response to the coronavirus. Early results seem promising, according to initial tests and a press release from the company.The company has submitted an application to the FDA to get emergency approval of their COVID-19 treatment. 1525
The Department of Labor reported Thursday that 1.5 million Americans filed initial claims for unemployment during the week ending June 20, bringing a 14-week total to about 46.5 million claims.Thursday's figures were down about 20,000 from last week's unemployment filings. It marked the third straight week where unemployment claims have hovered at about 1.5 million.Weekly claims for unemployment have been falling for about three straight months after peaking at about 6 million a week in late March. But weekly unemployment claims remain historically high.Prior to the pandemic, the record high for weekly unemployment claims came in 2006, when 665,000 people filed for unemployment. The Department of Labor has been tracking the statistics since 1967.Economists often use weekly unemployment claims as a reliable tool when predicting unemployment. However, some surveys indicate that initial weekly claims may be underestimating the amount of those unemployed.At least one survey from the Economic Policy Institute found that millions of Americans gave up trying to seek benefits or didn't even attempt to due to states' overwhelmed and antiquated unemployment systems.The economy has improved slightly since the virus first arrived in the U.S. earlier this year. Every state had begun the process of restarting its economy as of earlier this month.However, new cases of COVID-19 are currently on the rise in many states, with reports of new infections nearing record levels — re-igniting fears that more lockdown restrictions could be on the way. 1560
The country’s cybersecurity agency says the hacking campaign discovered earlier this month was “impacting” local governments, in addition to federal and state entities and businesses.In a statement this week, CISA said they are still tracking the “significant cyber incident impacting enterprise networks across federal, state, and local governments, as well as critical infrastructure entities and other private sector organizations.”However, the agency did not give specific examples or further details like how many state and local governments were impacted. The hackers were able to get access to government and business networks through the IT management company SolarWinds’s Orion software supply chain, which are used by government and private businesses. The hack was discovered this month, however officials believe it has been going on for several months.CISA says just because we are aware of the hack doesn’t mean the threat is gone. They warn the hackers have “the resources, patience, and expertise to gain access to and privileges over highly sensitive information if left unchecked. CISA urges organizations to prioritize measures to identify and address this threat.”Last week, the Cybersecurity and Infrastructure Security Agency said the hack posed a “grave threat” to security U.S. government agencies, critical infrastructure entities and private groups.CISA also said at the time the SolarWinds Orion vulnerability was not the only way that hackers were able to get into government agencies, private companies and critical infrastructures over the last several months."CISA has determined that this threat poses a grave risk to the Federal Government and state, local, tribal, and territorial governments as well as critical infrastructure entities and other private sector organizations," the alert issued by the agency said. "CISA expects that removing this threat actor from compromised environments will be highly complex and challenging for organizations."So far, several federal agencies, including the Treasury and Department of Energy, have indicated they were impacted, and Microsoft is reporting in a blog post more than 40 customers around the world appear to have been targeted in the hack.Multiple U.S. officials have implicated Russia in the hack. However, President Donald Trump has not said much about it, other than a tweet that eluded it may have been China who was responsible. 2426
The Christian evangelist who attempted to convert one of the world's last remaining isolated tribes wrote of his convictions in pursuing the mission even in the face of open hostility and attempts on his life, according to diary entries and notes.In excerpts from his journal, John Allen Chau, the American who is believed to have been killed by members of the isolationist Sentinelese tribe on a tiny, remote island in the Bay of Bengal, wrote of returning to the island to continue his attempts at conversion even after a tribesman shot at him with a bow and arrow, piercing a Bible he was carrying."I hollered, 'My name is John, I love you and Jesus loves you,'" he wrote in his diary, pages of which were shared by his mother with the Washington Post. Shortly after, a young member of the tribe shot at him, according to his account.In pages left with the fishermen who facilitated his trip to the island, his musings are a clear indication of his desire to convert the tribe."Lord, is this island Satan's last stronghold where none have heard or even had the chance to hear your name?" he wrote.His notes indicate that he knew the trip was illegal, describing how the small fishing vessel transported him to the isolated island under cover of darkness, evading patrols."God Himself was hiding us from the Coast Guard and many patrols," he wrote.All seven locals who facilitated the trip have been arrested. 1419
The former football coach for The Ohio State University, Earle Bruce, died early Friday morning, ESPN reports.Bruce was the coach for the Buckeyes from 1979 to 1987 and had the difficult task of replacing legendary Buckeyes coach Woody Hayes. He was well-regarded, leading the team to four Big Ten titles and had a 5-3 record in bowl games. A number of his players, such as Jim Lachey, Keith Byars and Pepper Johnson, went onto pro careers. 478