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LA JOLLA, Calif. (KGTV) - A researcher at UC San Diego just got a million grant to further his work into nanosponge therapy.Liangfang Zhang, a professor of nanoengineering and bioengineering, has been working on creating macrophage cellular nanosponges, tiny particles covered in white blood cell membranes, to treat sepsis and other diseases."They can be used to bind to the virus and neutralize the virus," Zhang says. "So now the virus would lose the ability to infect the host cells."The nanosponges act as decoys, tricking a disease or virus into binding with them instead of with human cells. While the initial aim is to treat sepsis, Zhang says it has applications to other deadly diseases, including COVID-19."The formulation that we're developing for treatment of Sepsis is the same formulation that you will use with COVID-19," he says.The grant comes from CARB-X, a Boston-based medical philanthropy that specializes in funding research into antibacterial treatments. Zhang says the money will be used for his company, Cellics Therapeutics, to further advance the research into clinical trials, FDA approval, and production of the nanosponge therapy.Steve Chen, president and chief medical officer of Cellics Therapeutics, says he's hopeful they can advance the nanosponges into human trials within two years."We're essentially looking at how this platform can treat not just infectious disease or future pandemics, but you could actually have a lot of applications in any type of autoimmune diseases or any type of inflammatory diseases," says Chen.In an early study published this year, Zhang's research showed the nanosponges were around 90% effective at blocking infections from taking hold.RELATED: UC San Diego researchers testing nanosponges to fight COVID-19Chen says the research and trial period may take too long for the nanosponges to be used during the current coronavirus pandemic. But he's hopeful it will help make the next outbreak less severe."My sincere desire is that we are not going to need this for COVID-19. But I think this does position us very well for any potential future kind of viral outbreak," says Chen.Cellics is also working on a Red Blood Cell version of their nanosponges, which may be ready for human trials within a year. 2283

JAMUL, Calif. (KGTV) — Four people were arrested after a 14-year-old was caught smuggling crystal meth through an East County checkpoint.The boy had three bundles of methamphetamine strapped to his body underneath his clothing as he traveled through a State Route 94 checkpoint on Monday night, according to U.S. Customs and Border Protection. A border K9 patrol of the vehicle during questioning alerted agents to the narcotics.During questioning of the 14-year-old and three other people in the vehicle, a second inspection with K9s was performed. The agents says they found three backpacks in the rear of the vehicle, containing 49 plastic-wrapped packages. The backpacks contained about 50 pounds of methamphetamine.The driver, a 34-year-old U.S. citizen, was arrested along with a 16-year-old US citizen and two Mexican national ages 14 and 16. Border agents seized the vehicle and turned over the narcotics and individuals to officers with the High Intensity Drug Trafficking Area task force.Since Oct. 1, 2019, San Diego Sector CBP says it has seized nearly 1,100 pounds of meth worth nearly .1 million on the street. 1135

JOSHUA TREE, Calif. (KGTV) - The San Bernardino couple accused of keeping their children in unsanitary conditions pleaded not guilty Friday to three felony counts of child abuse, KABC reported.Mona Kirk, 51, and Daniel Panico, 73, appeared in Joshua Tree Superior Court.San Bernardino Sheriff’s deputies were checking the area near their home Wednesday afternoon and found a trailer that appeared to be abandoned. Also on the property was a large plywood box.A further inspection showed no electricity or running water, and large mounds of trash and human feces.Prosecutors said the couple did not provide the 11, 13 and 14 year old children with enough food.Almost four dozen cats were on the property.RELATED: Perris couple accused of shackling, abusing childrenKABC reported the couple's friends said the family was homeless.A judge ordered Kirk and Panico to be held on 0,000 bail, according to KABC.  921

JERUSALEM (AP) — The international force that monitors the four-decade-old Israeli-Egyptian peace agreement has confirmed the deaths of eight peacekeepers in a helicopter crash in Egypt's Sinai region.The Multinational Force and Observers said six Americans, a French and a Czech were killed. It said a ninth peacekeeper survived and was evacuated for medical treatment.Names of the deceased are being withheld until next of kin are notified of the deaths.The force says “all indications” are that the crash was an accident, but it will still be investigated to determine a cause.The peacekeepers are responsible for monitoring troops levels and protecting free navigation in the area.Thirteen countries contribute troops to the force, with the U.S. providing the largest contingent.Acting Secretary of Defense Chris Miller issued this statement regarding the deaths: 875

Jerry George, a former senior editor at American Media Inc, says the reported payoff to a former Trump building doorman shows how complicit AMI chief David Pecker is in buying stories to protect President Trump's reputation, racking up what George called a "favor bank" of killed stories.Media outlets, including The New Yorker, have reported that AMI paid Dino Sajudin, a former doorman at Trump World Tower in Manhattan, ,000 in late 2015 for his account of an unproven rumor that Trump had an affair with an employee in the late 1980s and fathered a daughter with her.A spokesperson for the Trump Organization said Sajudin's claims were false, and disputed that Matthew Calamari -- who The New Yorker reported is Trump's head of security -- told Sajudin about a "love child.""Not only did Mr. Calamari never make these statements, but a simple internet search shows that Mr. Sajudin is alleged to have a long history of peddling false and malicious stories for his own benefit," the spokesperson said. "Given these accusations, it is disappointing - though not surprising - that The New Yorker would give any credence to this story."While George does not have direct knowledge that Pecker was involved with the decision to pay Sajudin, he spoke about a long-running practice of the AMI chief killing unflattering stories about Trump.Asked to estimate how many Trump stories Pecker killed, George said "dozens of stories and hundreds of story leads that come in on the tip line that never see the light of day."Pecker is a longtime friend of the president.George, who worked for AMI for 28 years until he was laid off in 2013, said it was uncommon for the National Enquirer to buy a story and not run it. George said the Sajudin deal was "very unusual.""The Enquirer doesn't buy stories and pay big amounts of money for stories that are not going to run," he said. "There is an obvious motive for buying it. It was to keep it off the market."The company said it killed the story, because after a month of reporting, its staff determined it was not true. No media outlet has proven the story to be true. In a statement Thursday, AMI denied Trump or his personal attorney Michael Cohen were involved in its decision to drop the story."The suggestion that David Pecker has ever used company funds to 'shut down' this or any investigation is not true," the statement said. "In addition, AMI and Mr. Pecker emphatically deny any suggestion that there might have been be any 'partnership' created which might influence any business ties in regard to AMI. These claims are reckless, unsubstantiated, and false."True or not, George said Pecker quashed stories about Trump for years."I remember sitting in story meetings where reporters would pitch Trump story after story and the editors would say 'No thanks, we're not interested in that,'" he said.Any story that was remotely negative about Trump would be killed, George said."I think every word [about Trump] that's been printed has been vetted by his attorney, his people, his representatives -- after David Pecker took over, because of their friendship," he said."I've talked to reporters that I worked with and that worked with other editors on [Trump] stories that told me they had to run it [whatever they were reporting] by the Trump Organization," George said."They [reporters] would tell them exactly what the story would say, or the story wouldn't be developed unless he or his rep gave the nod, " he added.George said he did not believe Pecker would pay Sajudin or former Playboy Playmate Karen McDougal -- whose deal with AMI not to talk about an alleged 10-month affair with Trump earned her 0,000 -- without telling Trump.He characterized Pecker's approach as, "This is what I've done for you. See how much I adore you?"George went on to say that it was "no coincidence that President Trump has been quoted saying David Pecker would be the perfect editor for Time Magazine."Trump tweeted the endorsement three times in 2013, writing on July 9: "@TIME Magazine should definitely pick David Pecker to run things over there - he'd make it exciting and win awards!"George described Pecker as a man driven by money and not by journalism."This guy doesn't have ink in his veins. He's a businessman," George said. "Pecker is all about money and, you know, the next big acquisition and who's going to fund it. I'm not saying he doesn't sincerely revere President Trump, but I guess it's sort of a favor bank where he can say to the president - I have an arsenal of stories that I have kept out of print, so these scandals never saw the light of day."George said he did not know of any examples of Trump funding acquisitions for Pecker.George said he had no knowledge about Pecker's relationship with Michael Cohen, Trump's personal attorney. Cohen said he paid porn actress Stormy Daniels 0,000 out of his own pocket just days before the 2016 election to keep quiet about an alleged 2006 sexual encounter with Trump.Representatives for Trump have repeatedly denied the alleged affairs with Daniels and McDougal. Trump has said he didn't know about the 0,000 payment.The latest report is part of an emerging pattern of payoffs by Trump allies to kill damaging stories about him, especially allegations that emerged during his long-shot campaign for the White House in 2015 and 2016.The-CNN-Wire 5365