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Gunshots rang out at a birthday party on Detroit's east side injuring multiple people.Police said at least three people were shot at during the party, and a fourth victim was hit down the street.Investigators say it happened around 11:20 p.m. Sunday at a home.Police say the victims are a 27-year-old woman shot in the face, a 32-year-old woman shot in the leg and a 40-year-old man shot also shot in the leg.  All three told police they were at a birthday party when two men started shooting.The fourth victim, a 31-year-old man down the street, says he was walking when two men walked up to him and shot him in the backside and ran away.That man says he hopped on one leg to his home where he called police.Police do not have a description of the suspects, they only know they are looking for two armed men.All of the victims are listed in temporary serious condition at Detroit Receiving Hospital.  924

Holidays will look different this year for many Americans, with dinners outside, social distancing, or passing on family gatherings altogether. But several companies developing rapid at-home COVID-19 tests are hopeful that won't be the case next year. The goal is to make inexpensive, easy-to-use COVID tests that can deliver results in minutes, just like a pregnancy test. "For people to feel comfortable to associate with friends or family, there needs to be a testing methodology ideally that can be performed at home," said Tony Lemmo, CEO of the manufacturing company BioDot.The company's technology is being used by over 70 manufacturers worldwide making COVID-19 antigen, antibody, and PCR tests. Their automated platforms dispense nanoliter/picoliter amounts of reagent onto the tests accurately and fast.Lemmo says just one of their systems can support the production of roughly 100 million COVID-19 tests per year, helping to make high-volume production possible.“We knew we were going to be called on by customers to manufacture more equipment to provide them the ability to manufacture more tests," said Lemmo. To meet customer demand, BioDot increased staffing and built a new facility, compressing production time from months to weeks. The FDA recently authorized the first rapid at-home test that can deliver results in 30 minutes, eliminating the need for a lab to test the sample. But the molecular single-use test will only be available to patients with a doctor's prescription who are suspected of being infected with COVID-19.Companies developing tests hope the FDA will soon authorize another at-home testing tool: the rapid antigen test.These inexpensive tests provide results within minutes, and companies developing them say millions could be sold without a doctor's referral.“From what we’re hearing, it’s really just a matter of possibly months before there’s at least sufficient data to be able to support an at-home use of a test like an antigen test," said Lemmo.Lemmo says if authorized by the FDA, manufacturers could make millions of these tests in a matter of months. But antigen tests are less accurate, and the FDA wants to ensure they'll be simple enough for people to use at home. There are also concerns over how the data will be reported to health authorities. “I think any at-home testing or massive rollout of a test into the communities needs to be done very carefully and with a lot of education around it," said Clinical Lab Director Melissa Miller. Dr. Miller is a professor of pathology and laboratory medicine at the University of North Carolina Chapel Hill and Medical Director for the Clinical Microbiology Lab for the Medical Center.She worries the inaccuracies of these tests could eventually lead the public to lose trust in all testing. “Even at 98 percent specificity, which is very, very high. That means you’re going to have a false positive two out of every 100. If you started testing a hundred million people, this is millions of people who have a false-positive test," said Dr. Miller. She says this could lead to healthy people isolating and missing work or school unnecessarily, and false-negative results could give people a false sense of security. “These rapid antigen tests were pushed out to skilled nursing facilities; this is a very high-risk patient population. This is actually where you want a very accurate test," said Dr. Miller. She says it’s unclear how well antigen tests detect the virus in asymptomatic patients but agrees more data is needed to figure that out.“It might make more sense for K-12 schools, or even college settings, where there’s less risk for a poor outcome if you have a false positive or a false negative," said Dr. Miller. But with a growing demand for convenient at-home testing, manufacturers are hopeful that in the months ahead, the FDA will soon open the door to new solutions. 3889

GREELEY, Colo. – Chris Watts is set to be sentenced Monday morning for the murders of his pregnant wife, Shanann, and their two young daughters after he pleaded guilty this month to the killings that roiled their Frederick community earlier this year.Watts, 33, is expected to receive life in prison without the possibility of parole after the possibility he might receive the death penalty went away due to his plea deal.19th Judicial District Attorney Michael Rourke could also speak following the hearing and it’s possible that the autopsy reports for Shanann, Bella and Celeste could be released in the hours or days that follow.On Thursday, a judge granted Watts’ parents the right to speak at the hearing. Shanann’s parents could also deliver victim impact statements in which they could ask the judge for a more-lenient or stronger sentence for Watts.That ruling, paired with The Denver Post’s interview of the woman with whom Watts was having an affair prior to the killings and an?interview with Watts’ parents, have made for high drama ahead of Monday’s hearing.Police arrested Watts late on the night of?Aug. 15 in the alleged killings of Shanann, Celeste and Bella. After Watts initially denied?that he killed them in an interview, police documents said that he admitted to doing so.Prosecutors said they believed Watts killed the three inside the family’s home in Frederick. The affidavit released in August confirmed details that had been previously reported, citing high-ranking sources, that Shanann’s body was buried in a shallow grave at the site and that the bodies of Celeste and Bella were put inside of oil and gas tanks at an Anadarko site in Weld County, where Watts worked before he was fired following his arrest.Chris Watts pleaded guilty Nov. 6 to nine counts in the deaths of his pregnant wife and two daughters: three counts of first-degree murder after deliberation, two counts of first-degree murder – victim under 12/position of trust, one count of first-degree unlawful termination of a pregnancy and three counts of tampering with a deceased human body.In exchange for the guilty plea, the death penalty was taken off the table. Rourke said earlier this month the deal was made with the agreement of Shanann’s family. 2270

Heavy rain, pounding surf and flash floods hit parts of the Florida Panhandle and the Alabama coast on Tuesday as Hurricane Sally lumbered toward land at a painfully slow pace, threatening as much as 30 inches (76 centimeters) of rain and dangerous, historic flooding.The storm’s center churned offshore 65 miles (105 kilometers) south-southeast of Mobile, Alabama, as Sally crept north-northeast toward an expected Wednesday landfall at 2 mph (3 kph), according to the National Hurricane Center. The forecast map showed the center likely coming ashore in Alabama, near the Florida line.Hurricane force winds extended 40 miles (65 kilometers). Rain fell sideways and began covering roads in Pensacola, Florida, and Mobile. More than 80,000 power customers were without electricity, according to poweroutage.us .Up to a foot (more than 30 centimeters) of rain had fallen already on the coast by Tuesday night and Sally’s lumbering pace meant there would likely be extended deluges.“A hurricane moving at 2 mph is stalled for all intents and purposes,” said Brian McNoldy, a hurricane researcher at the University of Miami. “If they aren’t moving along and they just kind of sit there, you’re going to get a ridiculous amount of rain.”Sally strengthened late Tuesday, with sustained winds reaching 90 mph (145 kph). Winds had reached 100 mph (161 kph) on Monday. The National Hurricane Center expected Sally to remain a Category 1 hurricane when it comes ashore, adding “historic life-threatening flash flooding is likely.”By Tuesday night, hurricane warnings stretched from coastal Mississippi to the Florida Panhandle. There also was a threat the storm could spawn tornadoes and dump isolated rain accumulations of 30 inches (76 centimeters) in spots from the Florida Panhandle to southeast Mississippi.Heavy rain and surf pounded the barrier island of Navarre Beach, Florida, on Tuesday and road signs wobbled in the wind. Rebecca Studstill, who lives inland, was wary of getting stuck on the island, saying police close bridges once the wind and water get too high. “Just hunkering down would probably be the best thing for folks out here,” she said.Two large casino boats broke loose Tuesday from a dock where they were undergoing construction work in Bayou La Batre, Alabama. M.J. Bosarge, who lives near the shipyard, said at least one of the riverboats had done considerable damage to the dock.“You really want to get them secured because with wind and rain like this, the water is constantly rising,” Bosarge said.In Orange Beach, Alabama, towering waves crashed onshore as Crystal Smith and her young daughter, Taylor, watched before nightfall. They drove more than an hour to take in the sight.“It’s beautiful, I love it,” Crystal Smith said amid whipping wind. “But they are high. Hardly any of the beach isn’t covered.”Capt. Michael Thomas, an Orange Beach fishing guide, secured boats and made other last-minute preparations. He estimated up to 5 inches (13 centimeters) of rain had fallen in as many hours.“I’m as prepared as I can be,” Thomas said.Stacy Stewart, a hurricane center senior specialist, warned that floods could be deadly.“This is going to be historic flooding along with the historic rainfall,” Stewart said. “If people live near rivers, small streams and creeks, they need to evacuate and go somewhere else.”Forecasters warned that Sally could unleash flooding similar to what Hurricane Harvey inflicted in 2017 in swamping the Houston metropolitan area.Mississippi Gov. Tate Reeves urged people in the southern part of the state to prepare for the potential for flash flooding. He said about 120 people were in shelters in Mississippi.As rain grew heavier Tuesday, many businesses appeared to be closed at exits along the Interstate 10 highway running along the Gulf Coast from Louisiana to Florida.In Gulfport, Mississippi, white plastic bags hung over some gas station pumps that were out of fuel. Along a bayou inland from the Gulf, three shrimp boats were tied up as shrimpers tried to protect their boats from waves. Metal storm shutters or plywood covered the windows of many businesses.In Alabama, officials closed the causeway to Dauphin Island and the commuter tunnel that runs beneath the Mobile River.Alabama Gov. Kay Ivey urged residents near Mobile Bay and low-lying areas near rivers to evacuate if conditions still permitted a safe escape. Revised forecasts late Tuesday predicted that storm surge along Alabama’s coast could reach 6 feet (1.8 meters) at Dauphin Island and as much as 4 feet (1.2 meters) at Mobile Bay.“This is not worth risking your life,” Ivey said.Once ashore, Sally was forecast to cause flash floods and minor to moderate river flooding across inland portions of Mississippi, Alabama, northern Georgia and the western Carolinas over ensuing days.President Donald Trump issued emergency declarations for parts of Louisiana, Mississippi and Alabama on Monday, and tweeted that residents should listen to state and local leaders.On the barrier island of Pensacola Beach, Florida, the Sandshaker Lounge was open Tuesday afternoon, filled with about 30 locals and tourists staying at nearby hotels.“I think I’m the only business open,” said bartender Kyra Smith. She said most locals have lived in the area for decades and have weathered many storms bigger than Sally.“We’re just going to ride it out,” she said.___Wang reported from Pascagoula, Mississippi. Associated Press reporters Jeff Martin in Marietta, Georgia; Russ Bynum in Savannah, Georgia; Sophia Tulp in Atlanta; Tamara Lush in St. Petersburg, Florida; Rebecca Santana in New Orleans; Emily Wagster Pettus in Jackson, Mississippi and Kim Chandler in Montgomery, Alabama, contributed to this report.Full Coverage: Hurricanes 5758

From Parkland to Pittsburgh, we all realize that these days a mass shooting can happen anywhere, at any time.If a shooter walked into your workplace, whether an office building, a school or a movie theater, would you know how to survive?They're words too many people have heard: "We have an active shooter. Stand by for further information."Jim Hardman is a Desert Storm US Army veteran and a former police officer who teaches survival classes.In an active shooting, he says everyone should know three keywords: run, hide, fight.First: Run.Hardman says wherever you are, always know where the exit is."I walk into a store or a new business," he said, "and ask myself where can I get out?"Hear gunshots? Hardman says run if you can, without running into gunfire."If I decide to run, I move with a purpose," he said. "I'm not just running through the center or a room to try to get away."Second: Hide.Hardman says to look for a spot that might stop bullets."I position myself to where I've got that filing cabinet, that copier, something that's heavy."Hardman says never try to reason with someone already shooting. Statistics show you cannot stop him at that point."Once that active killing starts, that rationalization is out the door."Obviously, your best bet is to escape. But if you can't get out, Hardman says the next thing to do is to start barricading the room you're in, putting heavy everything at the door to keep the shooter out."I might just grab an entire desk assembly, slide it over in front of the door, " he said. 1553