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The United States State Department has lifted a worldwide Level 4 travel advisory which had been in place since the spring amid the spread of the coronavirus.A Level 4 advisory is the highest alert level at the State Department, which warns travelers of life-threatening risks.The State Department still has a number of Level 4 advisories across the globe, including neighboring Mexico.The change in status, however, might not have much impact on travelers as many countries have placed strict limits on non-essential travel from the United States. And with the United States still leading the world in coronavirus cases and deaths, Americans ability to travel internationally is expected to be limited for months to come. 730

The winds were so strong on July 26 in Redding, California, authorities say they uprooted trees, ripped roofs off houses and downed power lines.The fast-moving Carr Fire took three family members from Ed Bledsoe that day -- his wife and two great-grandchildren."The tornado was hovering over the house," Amanda Woodley, Bledsoe's granddaughter, told CNN. "It was just a tornado fire over the house."Bledsoe had left the house earlier to go to the doctor's office, and was on the phone with his family members as the flames closed in. They believed they were safe from the fire and knew nothing of the approaching hellscape that was like nothing any of them had ever seen before.He said his son drove toward the flames in the hope of rescuing his family members. "My son said the grass wasn't on fire, the trees were getting sucked up in the air and burning," Bledsoe told CNN. "He said when he opened his doors, the leaves hit him like somebody was slapping him. He said it was sucking his breath out, and he got back in his car and tried to get out."Bledsoe was on the phone with his wife and great-grandchildren until the very end."It sucked the roof off the house and the walls fell out and the roof went right down on them," he said.The Carr Fire, now the sixth most destructive fire in California history, has consumed 121,000 acres and killed six people.Dr. Craig Clements of San Jose State University's Fire Weather Research Laboratory said there have been few observed firenadoes of this magnitude before. He says the conditions have to be perfect for something like this to occur.Firenadoes are formed from a fire's intense heat, causing the air to heat up quickly and rise rapidly. That, combined with surface winds that are obviously quite strong, creates a vortex similar to a dust devil.Clements says aside from the potentially damaging winds, a firenado like this can even pull fire in different directions.At 3:27 p.m. that day, the National Weather service sent out a statement noting that "radar indicates strong rotation located within the intense fire activity of the Carr Fire." They warned of possible wind gusts up to 50 mph."The wind went from zero wind to 40 to 60 mph winds within 15 minutes," Justin Sanchez told CNN. He said his house was consumed by the firenado. "(There was) a loud disturbing deep growling noise as it spun around in a spiral. It seemed the outside was moving around so slowly, with two-foot sized pieces of debris floating in it."Sanchez says when he and his family were about a mile and a half from his home, they looked back and could see their neighborhood consumed by it. 2631

The US Food and Drug Administration approved two cancer treatments, Vitrakvi and Xospata, this week after expedited reviews.Vitrakvi, approved Monday, is "a treatment for adult and pediatric patients whose cancers have a specific genetic feature (biomarker)."The FDA said in a statement that it is the second approved cancer treatment that is based on a tumor biomarker instead of the place in the body where the tumor originated.Vitrakvi will be used for the treatment of solid tumors that have an NTRK (neurotrophic receptor tyrosine kinase) gene fusion that do not have a known resistance mutation, that are not metastatic or where surgical removal is likely to lead to severe morbidity, and that have no alternative treatments or have progressed after treatments.NTRK genes are rare but occur in many types of cancer, the FDA said, such as mammary analogue secretory carcinoma and infantile fibrosarcoma.Xospata tablets, approved Wednesday, are for the "treatment of adult patients who have relapsed or refractory acute myeloid leukemia (AML) with a FLT3 mutation," according to the FDA.Alongside the tablets, the agency also approved a diagnostic to detect the mutation."Approximately 25 to 30 percent of patients with AML have a mutation in the FLT3 gene. These mutations are associated with a particularly aggressive form of the disease and a higher risk of relapse," Dr. Richard Pazdur, director of the FDA's Oncology Center of Excellence, said in the statement.AML is a rapidly progressing cancer that affects the numbers of normal blood cells and calls for continuous transfusions, the FDA said.Both treatments were granted Priority Review designation.Priority Review, established in 1992, means the FDA aims to review the drug or treatment within six months, opposed to 10 months for a standard review."A Priority Review designation will direct overall attention and resources to the evaluation of applications for drugs that, if approved, would be significant improvements in the safety or effectiveness of the treatment, diagnosis, or prevention of serious conditions when compared to standard applications," the FDA says.Both treatments also received?orphan drug?designation, a status granted to drugs for rare diseases or conditions. 2261

The Saharan Air Layer remains quite active as dust continues to stream west off the African coast. The initial plume is currently over much of the Southeast US with another large plume approaching the Caribbean. Here is the latest (Fri June 26) 10 day computer model dust forecast pic.twitter.com/0KUxLkOkjA— NWS Eastern Region (@NWSEastern) June 26, 2020 363

The United States set another record for daily confirmed coronavirus cases as several states posted all-time highs, underscoring the vexing issue confronting President Donald Trump or Joe Biden as a perilous pandemic surges with the holidays and winter approaching. The surging cases and hospitalizations happening around the country reflect the challenge that the winner of the too-early-to-call presidential race will face in the coming months.According to the New York Times, 1,130 coronavirus-related deaths were reported on Tuesday. The average number of deaths, while increasing, is not increasing at the same rate as cases. According to a Harvard risk assessment map, 26 states are are the highest alert level where 25 cases per day per 100,000 people. The states are mostly located in the central US. The map shows that North and South Dakota are experiencing the most widespread cases of the coronavirus. 921