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WASHINGTON, Jan. 2 (Xinhua) -- A hormone derived from visceral fat called adiponectin may play a role as a risk factor for development of all-cause dementia and Alzheimer's disease (AD) in women, according to a study published on Monday in online issue of the Archives of Neurology.Thomas van Himbergen, from Human Nutrition Research Center on Aging at Tufts University, and colleagues measured levels of glucose, insulin, and glycated albumin, as well as C reactive protein, lipoprotein associated phospholipase A2, and adiponectin in the plasma of patients at the 19th biennial examination (1985 -- 1988) of the Framingham Heart Study.The 840 patients (541 women, median age of 76 years) were followed-up for an average of 13 years and evaluated for signs of the development of AD and all-cause dementia. During that time, 159 patients developed dementia, including 125 cases of AD. After adjustment for other dementia risk factors (age, low plasma docosahexaenoic acid, weight change) only adiponectin in women was associated with an increased risk of all-cause dementia and AD."It is well established that insulin signaling is dysfunctional in the brains of patients with AD, and since adiponectin enhances insulin sensitivity, one would also expect beneficial actions protecting against cognitive decline," the authors write. "Our data, however, indicate that elevated adiponectin level was associated with an increased risk of dementia and AD in women."
BEIJING, Jan. 20 (Xinhuanet) --The air quality has worsened in the Chinese capital since Wednesday, triggering renewed discontent among residents.Without rainfall and wind to dispel pollutants, particulate matter has been accumulating in the air. Most monitoring stations measured PM 10 (particulate matter smaller than 10 micrograms) at higher than 300 micrograms a cubic meter.In southwestern Beijing's Fangshan district, the Liangxiang station recorded 516 micrograms of PM 10 a cubic meter, the highest reading of the day, according to the Beijing Municipal Environmental Monitoring Center.More than 150 micrograms a cubic meter is considered hazardous to health.Beijing has been shrouded by heavy smog off and on this winter, and the ongoing air concerns are wearing on residents particularly as they prepare to celebrate the Spring Festival holiday next week."I almost got choked by the smog when I stepped out of the office building on Wednesday," said Yang Yanli, 24, an accountant. "The smell is so terrible, as though I'm inhaling chunks of coal, that it has spoiled my holiday mood.""PM 10 intensity has been particularly high these days," said Wang Qiuxia, a researcher at the Green Beagle, a non-governmental organization based in Beijing.Unlike the smog that hit mostly the southern part of the capital on Jan 1, the smog in recent days has shrouded the entire city, according to the Beijing environmental protection bureau.Worse yet, it will linger until Saturday, when the wind will pick up and disperse it, the bureau predicted.The Chinese Center for Disease Control and Prevention suggests people stay at home to protect themselves from respiratory and heart problems triggered by heavy smog."The intensity of indoor pollutants is 30 to 60 percent lower than those outdoors during a hazy day," said Xu Dongqun, an officer with the environmental bureau. "I suggest people with respiratory problems put off traveling if the smog lingers."But many people said they had to brave the foul air to travel, especially migrants who are eager to reunite with their families during Spring Festival."No one likes to travel when the air is this bad, but do you have any choice when Spring Festival is coming?" asked Feng Xiao, a public servant at China's General Administration of Sport. The 24-year-old plans to travel by train from Beijing to her hometown in East China's Shandong province on Friday.

UNITED NATIONS, Nov. 21 (Xinhua) -- Dramatic progress in science, political leadership, and results indicate that 2011 was a "game changing" year for the international AIDS response, and much progress has been made in 2011 to check AIDS-related deaths since 1997, the peak of the epidemic, a new report released by the Joint United Nations Program on HIV/AIDS (UNAIDS) said on Monday."The Report on the Global AIDS Epidemic 2011" found that new infections were reduced by 21 percent since 1997, and deaths from AIDS-related illnesses decreased by 21 percent since 2005, according to the report.Furthermore, 47 percent (6.6 million) of the estimated 14.2 million people eligible for antiretroviral therapy treatment in low- and middle-income countries were accessing treatment, in increase of 1.35 million people since 2009.The report also found early signs that HIV treatment is having an impact on reducing the number of new HIV infections. As treatment reduces the viral load of a person living HIV to almost undetectable levels, it also reduces the risk of transmitting the virus to an uninfected partner, according to the report. Studies also show that treatment can be up to 96 percent effective in preventing HIV transmission among couples.Eleven countries, including many Sub-Saharan African countries, reached "close to universal access" for AIDS treatment, which is determined to be 80 percent access, in 2011.Botswana made the most dramatic progress in scaling up access to treatment, the report said. While sexual patterns remained relatively stable in the country since 2000, access to treatment increased from less than 5 percent in 2000 to more than 80 percent in 2011.Despite progress, however, the report does note that 2011 marks an unprecedented high the number of people infected with HIV worldwide.Globally, an estimated 34 million people are currently living with the infection. Approximately 2.7 million got infected with the virus in 2010, and as many as 1.8 million people died of AIDS- related illnesses in 2010.Yet the report also notes estimates that as many as 2.5 million deaths are estimated to have been averted in low- and middle- income countries due to increased access to HIV treatment since 1995."Now is not the time to reduce our efforts despite some good news on reducing new infections. Infections are decreasing, but not rapidly enough," said Kim Nichols, executive director of African Services Committee, on Monday at a press conference."There are fewer AIDS deaths, but with the number of infections increasing, prevention has to be the mainstay of our response," Nichols said.Indeed, the UNAIDS report calls for a new framework for investments which are focused on "high-impact, evidence-based, high-value strategies," according to a press release from the UNAIDS website.The framework, which aims to achieve universal access to treatment and prevention centers by 2015, requires a 22-24 billion US dollar funding increase by 2015.Given the withering state of the global economy -- donor funding for the AIDS response has dropped from 7.6 billion in 2009 to 6.9 billion in 2010 -- raising that kind of money may be a long shot. Regardless, UNAIDS'new investment plan calls for smarter uses of less money.According to the report, the framework will focus on high-risk populations like sex workers, men who have sex with men, and people who inject drugs and prevent infections among children, as well as invest in behavior change programs, condom promotion, and treatment, care and support for people living with HIV."The world faces a clear choice: maintain current efforts and make incremental progress, or invest smartly and achieve rapid success in the AIDS response," says the UNAIDS report.
UNITED NATIONS, Nov. 18 (Xinhua) -- China on Friday voiced its hope that countries concerned "will continue to appropriately address the issue" of the alleged plot to kill Saudi Arabian ambassador to the United States "through dialogue and make joint efforts to maintain peace and stability in the Middle East and the Gulf region."The statement came as Li Baodong, Chinese permanent representative to the United Nations, was addressing the UN General Assembly to explain the Chinese position on the issue after he abstained from voting on the draft resolution on the alleged Iranian involvement in the assassination plot."China hopes countries concerned will continue to appropriately address the issue through dialogue and make joint efforts to maintain peace and stability in the Middle East and the Gulf region," he said."At present, the case is highly complicated and sensitive," Li said. "Parties still have different views over the issue. Any conclusion or action must be based on comprehensive, impartial, objective and transparent investigation and substantial evidence.""Before facts are out, parties should adopt a prudent approach, refrain from jumping to conclusions, and avoid action that may complicate and worsen the situation," he said."China abstained from the vote on the General Assembly draft resolution entitled 'Terrorist Attacks on Internationally Protected Persons'," he said. "We oppose all forms of terrorism, and always stand for compliance with international law and the basis norms governing international relations in handling state-to- state relations as well as effective protection of the safety and security of diplomatic personnel."Earlier on Friday, the UN General Assembly adopted a resolution which expressed deep concerns at the assassination plot and called on Iran "to comply with all of its obligations under international law." Iran strongly denied the allegation.Before or after the vote, countries such as Bolivia, Sudan and Venezuela said that due to a lack of solid evidence to support the allegation, the draft adoption would "create a dangerous precedent " in the international relations.
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