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SAN DIEGO (KGTV) — A Sorrento Valley company is working to create an implant that will help people kick their addiction to both opioids and alcohol.BioCorRx, based in Orange County, is developing the implant. They chose San Diego-based Irisys Therapeutics to help them build it."It’s not going to fix the opioid crisis," says BioCorRx CEO Brady Granier. "But it’s going to be another tool in a tool chest of those people looking for another solution and one that will help them get through the cravings."The implant uses Naltrexone, a drug already approved by the FDA as an every-day pill or a once-per-month shot. Naltrexone blocks receptors in the brain so that opioids or alcohol won't have any effect on people who use them. It also helps curb cravings."As long as it’s blocking the receptor, the opioids come in, and they can’t engage with that receptor to give you the euphoria or the respiratory depression that leads to overdose," says Granier. "It’s protecting you."Granier says creating an implant that lasts three months will make it more likely that people will be able to beat their addition. The implant, named BICX102, would be implanted into a person's stomach fat and dissolve slowly over three months."The goal is to give someone a longer period of time to address those issues without the intrusive cravings coming in," he says. "A lot of behavioral changes can take place in 90 days that you can’t do in 30."Granier's company just received a .7 million grant from the National Institute on Drug Abuse. It will last two years, which Granier says will fund the research through the development of the implant and some early testing.He's hoping to start human testing by 2020.Granier says implants like the one he is hoping to create are already available in other countries. But the FDA has yet to approve one in the US, where standards are more strict."The first pellet you make needs to be exactly the same as the 10,000th," he says. "It has to be a precise process."It's personal for Granier, who has family members with addiction in their past. He also worked as a nurse before starting his company. Granier says he saw the destructive effects of addiction every day. Now he's hoping to find a solution."It’s rare to find a good opportunity where you can make a social impact and be an entrepreneur at the same time," he says. 2358
SAN DIEGO (KGTV) - A young man was trapped in his car after a crash on southbound Interstate 15 at I-805 Monday afternoon.The solo-vehicle crash happened about 1:30 p.m. The man went off the freeway and into a tree, leaving his car a mangled wreck.San Diego Fire Captain Steve Salasz described the rescue as a “complicated effort”.Several firefighters used saws to free the man, whose foot was stuck in a floorboard.The man, who was alert and talking during the rescue, was taken to Scripps Mercy Hospital for treatment.There was no word on his condition but Salasz described his injuries as “severe”.Investigators did not release the cause of the crash. 662

SAN DIEGO (KGTV) - A San Diego mom is hoping the county's new plan to provide more affordable housing will help keep her off the street. Leticia Rodriguez, her mom, and two kids have been living in Rodriguez's van the last several months, but right now the van is in the shop. They're hoping to get into the San Diego Rescue Mission. It would be their first time sleeping at a shelter."You have to come back at 5 ' o'clock and line up and you know, wait to get in, every day, until you get a bed," said Rodriguez. Rodriguez makes an hour as a team leader at Jack N' The Box. She's been looking for a place she can afford for more than a year. "You can get a studio for 0 then you're lucky, but then they say how many are you? Then they say, that's too many," said Rodriguez. Tuesday the San Diego County Board of Supervisors voted unanimously to set up a million dollar trust fund for the county to use to invest in affordable housing. The vote followed a brief presentation by staff detailing the housing-related hurdles in the San Diego region, including that more than 3,500 affordable units have been lost in the last 20 years. 1192
SAN DIEGO (KGTV) - A woman was arrested Thursday on suspicion of running over and killing a man she had been arguing with at a Kearny Mesa parking lot. San Diego police said 33-year-old Latisha Ingram and an unidentified 25-year-old man were arguing in a parking lot in the 4600 block of Convoy Street at around 11:30 p.m. Thursday when the altercation escalated. Kiana Smith was in the middle of her shift at Rakiraki ramen restaurant when she heard the noise outside. Ingram was belligerent, Smith said, adding she had been turned away by a bartender at O’Brien’s. "She turned her down because she was way too drunk, then she made her way this way, and a server saw her before I did, saying she was way too drunk, she couldn't even walk." Smith told 10News the male victim, who had been waiting on a table with his girlfriend, was trying to stop Ingram from driving. "It looked like she was trying to get in her car, but she was obviously way too drunk to drive, so the guy was trying to stop her from driving,” said Smith. According to police, Ingram then drove away while the man was holding onto her car. Police said Ingram drove out of the parking lot and turned southbound onto Convoy Street when the man let go and was allegedly run over. "He ended up on the hood, and she made the right turn, and he completely flew off," said Smith.The man was rushed to the hospital, where he died from his injuries, police said. 10News learned Ingram returned to the area about 30 minutes later and was arrested without incident. Ingram was booked on suspicion of felony hit-and-run and felony DUI. 10News learned she has a prior DUI charge from 2011. Smith said returning to work Friday was tough. 1702
SAN DIEGO (KGTV) — An 18-year-old behind the wheel of a sports car involved in a fatal crash on Interstate 805 Thursday reportedly made a small fortune with YouTube videos.The California Highway Patrol confirmed Trevor Heitmann was behind the wheel of the 2014 McLaren sports car that struck a Hyundai SUV on I-805, killing himself, a 43-year-old Aileen Pizarro and her 12-year-old daughter, Aryana.Heitmann was traveling southbound in a northbound I-805 HOV lane at more than 100 mph, before colliding with the SUV and causing a chain reaction with at least five other vehicles, according to California Highway Patrol.RELATED: 12-year-old among victims in fiery wrong-way crash on Interstate 805Prior to the wreck, CHP said Heitmann’s vehicle was linked to an incident at Ashley Falls Elementary School in which he drove his McLaren through a gate and broke a window.Questions arose soon after the deadly crash of how an 18-year-old could afford the expensive sports vehicle.Heitmann, who went by the online persona "OG-McSkillet" according to numerous gaming websites, reportedly made a small fortune through YouTube videos about the video game Counter-Strike: Global Offensive, which were sponsored.His YouTube channel has nearly 900,000 subscribers and he has at least 200,000 followers on Twitter, offering a glance at the reach his sponsored videos had within the eSports gaming industry.RELATED: Popular YouTuber identified in wrong-way I-805 crashOne of the videos on McSkillet's page shows off a black McLaren and talks about how his earnings as a YouTube and Counter-Strike "Steam" content producer helped pay for the luxury sports car.Heitmann's popularity surrounded his trading and collection of rare video game content, called "skins," which are pieces of content for Counter-Strike players.He was banned earlier this year from trading skins with other players by the video game's developer, Valve. The "trade ban" cut him off from his collection, believed to be valued at anywhere from 0,000 to 0,000 at the time, and created an issue with his ability to continue producing sponsored videos.10News spoke to a woman off camera in Carmel Valley who knows the Heitmann's. She said, while Trevor had many fans worldwide, her son was one of his few close friends. According to her, Heitmann dropped out from La Jolla Country Day School. As Heitmann saw his few friends going off to college, she said he felt he was left alone at home.He was then "trade-banned," his website and merchandise websites were shut down, and his income stopped. She told 10News her son got messages from Heitmann a few weeks ago, rambling, and spewing irrational thoughts. She remembered Heitmann to be a nice young man from a great family. She believed something must have been going on internally for this to happen. RELATED: Video: YouTube shooter Nasim Aghdam's encounter with police before shootingValve reportedly banned Heitmann over his involvement with the gambling website CSGO Magic, which allowed players to spend actual money for the chance to win skins.By now, you're wondering what skins are and how they are valued so highly. Here's an explainer on how they work in online gaming:WHAT ARE SKINSSkins are unique visual designs for weapons in the online game Counter-Strike: Global Offensive (CS:GO). While the skins can be highly valued, they don't change the performance of the game or player, or affect the game's play in any way. They're purely aesthetic.HOW YOU GET SKINSPlayers acquire these special finishes for their weapons as a reward for playing the game, by purchasing them through the game's store, or by purchasing them or trading with another player within Steam, which is where gaming company Valve distributes digital content, like CS:GO, to gamers.All transactions that occur within Steam's market require players to use digital currency, deposited in a Steam Wallet. Players deposit actual money, say using a Steam gift card, into this online wallet.Valve takes a 15 percent cut of all purchases made on Steam's market.Any one item on Steam's marketplace cannot exceed a sale price of 0. Gamers can not have more than 0 in their Steam Wallet. Funds within a Steam Wallet cannot be taken out.PURCHASES MADE OUTSIDE STEAMThis is where gamers get around Valve's buying and selling requirements.Players can buy, trade, and sell skins on a third-party website that connects to a player's Steam account, with no price limits.These third-party sites let customers cash out using services such as PayPal, so money is not locked in their account, like a Steam Wallet.GAMBLING WITH SKINSThird-party websites have also allowed for players to gamble with skins.This is how it works: Players place bets using CS:GO skins on a third-party website. The winner gets their skins back, along with the skins wagered by the losing player.Players can then turn a profit, selling those skins they've just won through the Steam market or a third-party website — where, as we said above, there are no price limits.In 2016, Valve cracked down on players betting CS:GO skins, citing violations in their user agreement.The company sent a cease and desist letter to more than 20 skin betting websites, demanding they stop using their technology as the basis of skin gambling, according to gambling news site The Lines. It's this crackdown that is connected to Heitmann's "trade ban" over involvement with a skin betting website.Skin betting, at the time, had become a multi-million dollar industry, according to the website.A STOCK MARKET TRACKS SKIN VALUESThe value of CS:GO skins can fluctuate over time, much like an actual stock. As we now know, this value can range from <云转化_句子> to 0 in the Steam market.Values for skins are dictated by how rare they are and how much users are willing to pay. This affects how players trade, buy, and sell – and wager – CS:GO skins. 6126
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