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TEMPE, Ariz. — It's a huge breakthrough for the highly contagious and deadly norovirus as researchers at the Arizona State University’s Biodesign Institute have come up with a vaccine made from plants.The norovirus is known as the perfect human pathogen. It can have you feeling awful for days, but researchers at ASU say a form of the tobacco plant may be the key to a vaccine.Also known as the cruise ship illness, norovirus hits nearly 20 million Americans every year. According to Andy Diamos, a post-doctoral researcher at ASU, the average person has the stomach bug five times in their life.“Norovirus is a horrible bug to get,” said Diamos. “It causes vomiting, diarrhea, all sorts of nasty stuff.”There is no vaccine for the highly contagious bug because it's notoriously difficult to produce in a lab, until now, thanks to Diamos and Hugh Mason with the Biodesign Center.“Genetic engineering has allowed us to design systems like plants to produce useful things like vaccines,” said Diamos.By using a form of the tobacco plant, researchers discovered that a harmless bacteria would help grow a norovirus vaccine when the proper genes are transferred to the leaves.“You can basically put in whatever genes you want and transfer those to the plant, so that's how we get the plant to make the vaccine,” said Diamos.According to Diamos, real viruses are surrounded by a shell that protects its genes. The vaccine that grows inside the tobacco plant is essentially that shell without the harmful insides.“If you give that to someone as a vaccine, it looks just like the real virus, but there is nothing on the inside,” said Diamos. “It can't cause disease; it can't actually infect you.”That's what makes these plant-based vaccines safe and effective.“One of the main reasons why we're focusing on plants is because they're so cheap to work with. These vaccines will hopefully be much cheaper to produce than traditional methods,” said Diamos.Many discoveries from ASU researchers hit the market, this one could too, but it needs further study and would eventually need to be picked up by a pharmaceutical company which could take years. 2154

Tailored Brands, which owns Men's Wearhouse and Jos. A. Bank, announced on Tuesday that they would be closing up to 500 stores due to the coronavirus pandemic.The company said in a press release that they would cut 20% of its corporate jobs by the end of the fiscal second quarter.“We have safely reopened almost all of our retail stores and look forward to helping our customers look and feel their best for their moments that matter," Tailored Brands President and CEO Dinesh Lathi said in the press release. "Unfortunately, due to the COVID-19 pandemic and its significant impact on our business, further actions are needed to help us strengthen our financial position so we can navigate our current realities. It is always difficult to eliminate jobs and say farewell to our friends and colleagues. I want to thank our teammates affected by these changes as well as those who continue to help us meet the challenges currently facing our industry and who remain dedicated to serving our customers.”The clothing company also announced that Chief Financial Officer Jack Calandra was leaving on July 31 and they appointed restructuring consultancy AlixPartners managing director Holly Etlin as their Chief Restructuring Officer. 1236

Texas Lt. Gov. Dan Patrick blamed Friday's massacre at a high school near Houston in part on "too many entrances and too many exits" on the campus, prompting some to mock his perspective as "door control.""From what we know, this student walked in ... with a long coat and a shotgun under his coat," said Patrick, a Republican who has an A+ rating from the National Rifle Association. "It's 90 degrees. Had there been one single entrance possibly for every student, maybe he would have been stopped." 508

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The Arizona state prison near Yuma is under lockdown after authorities were able to contain a riot involving hundreds of inmates Thursday night.Inmates reportedly attacked prison personnel around 6:45 p.m local time at the medium-custody Cheyenne Unit of the complex.Officials say around 600 inmates were involved in the disturbance, which included throwing rocks, setting fire to mattresses and other property in the yard and breaking into the prison health unit. ADC response and tactical teams from Yuma, Lewis, and Tucson complexes brought the incident under control around 9 pm., according to a statement from corrections officials.All prison staff are safe and accounted for.The inmates involved are being contained in a fenced recreation yard as ADC investigates. Additional criminal charges are pending for any inmates involved in violent activity.  900