中山胃肠医院(中山治疗痔疮的最好方法) (今日更新中)

WASHINGTON, Aug. 2 (Xinhua) -- The weakness of aging is associated with leaky calcium channels inside muscle cells and a drug already in Phase II clinical trials for the treatment of heart failure might plug those leaks, according to a report published Tuesday in the online edition of Cell Metabolism.Earlier studies by the research team led by Andrew Marks of Columbia University showed the same leaks underlie the weakness and fatigue that come with heart failure and Duchenne muscular dystrophy."It's interesting, normal people essentially acquire a form of muscular dystrophy with age," Marks said. "The basis for muscle weakness is the same." Extreme exercise like that done by marathon runners also springs the same sort of leaks, he added, but in that case damaged muscles return to normal after a few days of rest. A microscopic view shows smooth muscle cells derived from human embryonic stem cells showing the nuclei (blue) and proteins of the cytoskeleton (green) in this handout photo released to Reuters by the California Institute for Regenerative Medicine, March 9, 2009The leaks occur in a calcium release channel called ryanodine receptor 1 (RyR1) that is required for muscles to contract. Under conditions of stress, those channels are chemically modified and lose a stabilizing subunit known as calstabin1.Calcium inside of muscle cells is usually kept contained. When it is allowed to leak out into the cell that calcium itself is toxic, turning on an enzyme that chews up muscle cells. Once the leak starts, it's a vicious cycle. The calcium leak raises levels of damaging reactive oxygen species, which oxidize RyR1 and worsen the leak.The researchers made their discovery by studying the skeletal muscles of young and old mice. They also showed that 6-month-old mice carrying a mutation that made their RyR1 channels leaky showed the same muscular defects and weakness characteristic of older mice.When older mice were treated with a drug known as S107, the calcium leak in their muscles slowed and the animals voluntarily showed about a 50 percent increase in the amount of time spent wheel running. Now in clinical trials for patients with heart failure, the drug is known to work by restoring the connection between costabilin and RyR1.Despite considerable effort to understand and reverse age- related muscle wasting, there are no established treatments available. The new work suggests there may be hope in approaching the problem from a different angle."Most research has focused on making more muscle mass," Marks said. "What's different here is that we are focused not on muscle mass but on muscle function. More muscle doesn't help if it is not functional."

BEIJING, June 7 (Xinhuanet) -- Sony Corp. on Monday unveiled its next generation portable gaming device, PlayStation Vita.The new PlayStation Vita will go on sale for 249 U.S. dollars, or 299 dollars for a 3G mobile version, starting in the holiday season, the Japanese electronics giant's No. 2 executive Kazuo Hirai told reporters on the eve of the E3 games convention.The device will allow gamers to be connected with one another over cellphone networks and Wi-Fi hotspots, and use GPS location-tracking technology. In the U.S., Sony is partnering exclusively with AT&T Inc. for cellphone service.Company executives have called the device Sony's biggest product launch since the PlayStation 3 five years ago."PlayStation Vita will revolutionize the portable entertainment experience," said Hirai. "The whole world is really in play."The handheld has front and back cameras, a touchscreen in front, a touch pad on the back and two knob-like joysticks. It will enable gamers to play against people using PlayStation 3 consoles over the Internet-based PlayStation Network.

WASHINGTON, July 18 (Xinhua) -- The U.S. National Aeronautics and Space Administration (NASA) on Monday commemorated the 90th birthday of astronaut John Glenn, the first U.S. astronaut to orbit the Earth and also the oldest person to fly to space when he launched on the space shuttle in 1998."John Glenn is a legend, and NASA sends him our best wishes on this major personal milestone," NASA Administrator Charles Bolden said in a statement. "John's legacy and contributions to the continued progress of human spaceflight are immense. His example is one we continue to emulate as we push toward farther destinations in the solar system."After a distinguished flying career with the Marines in World War II and Korea, Glenn joined NASA in 1959 as one of the country' s first astronauts in Project Mercury. On Feb. 20, 1962, Glenn piloted the Mercury-Atlas 6 "Friendship 7" spacecraft on the first U.S. manned orbital mission. He launched from NASA's Kennedy Space Center in Florida to successfully complete three orbits of the Earth.Glenn flew to space again on the STS-95 mission in 1998 aboard the space shuttle Discovery. As a mission specialist, Glenn supported deployment of a variety of research payloads and participated in investigations about spaceflight and the aging process.

BEIJING, Sept. 26 (Xinhua) -- Nobel laureates on Monday cast doubt on a European experiment that purportedly demonstrated the ability of neutrinos to move faster than the speed of light.They made the remarks in Beijing prior to a forum for Nobel laureates."I'm willing to bet money that it's not correct," said Professor George Smoot III, winner of the 2006 Nobel Prize in Physics and a professor at University of California, Berkeley, referring to an experiment result claiming that particles apparently travel faster than light.The experiment reported an anomaly in the flight time of neutrinos, or electrically neutral subatomic particles, from the European Center for Nuclear Research (CERN) in Switzerland to a laboratory located 730 kilometers away in Italy.Particles were clocked transmitting at a speed of 300,006 kilometers per second, about 60 nanoseconds faster than the speed of light.Smoot said that the claims "did not make sense" and should be verified by other scientists first."There are many distortions in physics. You have to have a very high standard to see if something is truly correct," he said.The unverified findings were published on Sept. 22 in the scientific journal Nature. European researchers working in a team called OPERA (Oscillation Project with Emulsion-Racking Apparatus) projected masses of neutrinos from CERN and then collected the particles using a massive detector in Gran Sasso, south of Rome.Other scientists, as well as the OPERA team themselves, have voiced doubts regarding the experiment's results.The findings, CERN claims, could pose far-reaching potential consequences once verified.If correct, the results would bring Einstein's theory of special relativity into question. Under this theory, a physical object cannot travel faster than the speed of light in a vacuum."If really it is right, we have to rethink everything we know," said Chris Llewellyn Smith, former director of CERN.Smith claimed the unprecedented discovery was too exceptional to find proof."If somebody makes a very exceptional claim, then very exceptional proof would need to come from another experiment, saying the same thing. But we don't have the other thing," Smith said.Carlos Rubbia, a Nobel Laureate who won the prize for physics in 1984, is in charge of a team of more than 100 scientists at CERN."What it is pretending to find, in my view, is unbelievably surprising," Rubbia said."Frankly, I have the feeling that this is still a very experimental consideration," Rubbia said.He also believes that revealing the findings to the public was a mistake as it remained an experimental process and no conclusion could be drawn without the results of another experiment.Despite the possibility of verification, Einstein's special theory of relativity will remain valid."I will be very, very surprised that, at last, Einstein will not be the winner," Rubbia said.To achieve a breakthrough, Rubbia has urged for more joint cooperation on verifying the test results. International cooperation on this issue "is a must.""It requires coordination from all nations," said Rubbia.The 2011 Nobel Laureates Beijing Forum will be held from Sept. 28 to 30 under a theme of "innovation and development."

BEIJING, Aug. 31 (Xinhuanet) – The pressure of modern society is taking a toll on sexual satisfaction, experts say following the release of an online survey.About 34 percent of people polled in the survey said that they are unsatisfied with their sex lives, with 6.5 percent "very unsatisfied".Another 32 percent condemned their sex lives as "just so-so".The survey interviewed more than 3,000 people, aged between 15 and 55, with men accounting for 74 percent of the interviewees.It was conducted by the China Population Communication Center and the Shanghai Academy of Social Sciences from May 1 to June 20. The survey did not give a margin of error.Only 23 percent of respondents said that they are "satisfied" with their sex lives, with 3.6 percent "very satisfied", according to the survey.But women seem to have a higher rate of satisfaction than men, with only 26 percent saying they are unsatisfied. The rate for men is 42 percent.The rate of sexual satisfaction among Chinese people is below the global average of 44 percent, according to an earlier survey by Durex. The 2007 Durex Global Sexual Wellbeing Survey questioned more than 26,000 people in 26 countries about all aspects of their sex lives - including satisfaction levels.Jiang Hui, president-elect of the Chinese Society of Andrology, attributed the lower rate of sexual satisfaction among Chinese people to rapid economic growth, which inevitably increases work and social pressure.Health problems associated with a modern lifestyle, such as diabetes and hypertension, are also to blame, he said.Jiang said his department of andrology used to receive about 10 patients a day 10 years ago. Now the figure has risen to more than 250.Rising awareness of sex and a more open attitude toward the once-taboo topic among the public also contributed to higher sexual expectations, he said.The survey also revealed that about 30 percent of respondents in the 35-55 age group had sex less than once a week."That rate is quite low, compared with the global average of 103 times a year, or 1.98 times a week," said Yang Xiong, who heads the social survey center at the Shanghai Academy of Social Sciences.Only 16.9 percent of respondents said that they had sex more than 10 times a month. Most respondents had sex three to nine times every month.About 8 percent of respondents said that they basically had no sex at all or it was too infrequent to be classified.The survey seemed to find that the more you made, the less you had. Those who earned at least 9,000 yuan (,400) a month had less sex than those who earned less, according to the survey.Among those making more than 9,000 yuan per month, over 70 percent said they had sex less than twice a month, compared with 16.5 percent for those with a monthly salary of less than 6,000 yuan.The survey also found that when people run into problems with their sex lives, 83 percent turn to the Internet, rather than professionals, for help. Less than 6 percent said they would see doctors to solve sex-related problems.Nearly 70 percent of those polled said they suffered from sexual health problems, such as erectile dysfunction (ED)."Many patients, especially men, are reluctant to see a doctor, which they think harms their manhood," Jiang said.According to a study conducted by the Chinese Society of Andrology, at least 40 percent of men aged 40 and above suffered from erectile dysfunction, roughly the global average.But Yang, from the Shanghai academy, noted that surveys conducted online tend to produce far different results than those conducted face-to-face.He expressed reservations about the survey's accuracy and said the public should only use the results for reference.

来源：资阳报