山东强直性脊柱炎病因及治疗(山东郑州强直性脊柱炎医院排名) (今日更新中)

LA JOLLA, Calif. (KGTV) - San Diego photographers, mark your calendars for Scrippshenge. Named for the ancient British site Stonehenge, where the sun lines up among ancient stones on the solstice, the sun lines up with the gap in La Jolla’s Scripps Institution of Oceanography pier on certain days of the year. The natural phenomenon makes for spectacular photos. This summer, Scrippshenge is set to take place August 7 - 9, according to the Photo Ephemeris app. “You might even get the shot on Aug 10/11 also, probably with a partially set sun,” says Stephen Trainor of Crookneck Apps. “You'll see the sunset line is ever so slightly to the north of the pier center: that's what you need, because sunset is the moment the sun disappears below the horizon, hence in order to frame the setting sun between the legs of the pier, it still needs to be just above the horizon, and therefore true sunset has to be just slightly to the north,” says Trainor. If you miss Scrippshenge, you can still enjoy the sunset at one of SIO’s Green Flash Concerts.RELATED: New Yorkers celebrate Manhattanhenge 1098

LANCASTER, Calif. – A man has been arrested for the murders of his 12-year-old son and 13-year-old daughter in Lancaster, California, which is north of Los Angeles.The L.A. County Sheriff’s Department said in a statement that fire personnel located the victims when they were called to the family's home to investigate a possible gas leak Friday morning.Detectives say the children both appeared to have suffered from lacerations and stab wounds.The mayor of Lancaster, Rex Parris, confirmed to KABC and the L.A. Times that the children were both found decapitated. He told the newspaper that “it was pretty brutal.”Officials tell the L.A. Times that the victims were found in separate bedrooms in the home and it’s unclear how long they had been dead.At the home, the sheriff’s department says there were also two adults and two other children who were questioned by homicide investigators. The L.A. Times identified the two adults as the victims’ parents.The children's father, Maurice Taylor Sr., was later arrested on murder charges and booked into jail, where he’s being held with a million bail.The L.A. Times reports the suspect is a personal trainer who acquaintances described as being “mellow” and “reliable.”Detectives say they’re continuing to investigate the murders. Anyone with information about incident is asked to contact the sheriff’s department’s homicide bureau at (323) 890-5500. If you prefer to provide information anonymously, you may call Crime Stoppers by dialing (800) 222-TIPS (8477). 1524

Laura Ingraham will leave Fox News's airwaves next week for a vacation.The anchor made the announcement when she signed off her show Friday evening, which capped a week of controversy in which she saw more than a dozen advertisers flee her show."A blessed Good Friday and Passover to all of you," Ingraham said. "I'll be off next week for Easter break with my kids."A Fox News spokesperson said the week-long absence was pre-planned.Advertisers bolted from "The Ingraham Angle" after the host sent a tweet earlier this week mocking David Hogg, one of the student-activists who became a voice for gun control after a shooter murdered 17 people at his high school in Florida last month.Ingraham's tweet included a link to a story on the right-wing news site Daily Wire that said Hogg was rejected by four colleges.Hogg then urged his 700,000 Twitter followers to contact Ingraham's advertisers and press them to boycott her prime-time show.On Thursday, after at least two companies had taken action, Ingraham apologized in a series of tweets."On reflection, in the spirit of Holy Week, I apologize for any upset or hurt my tweet caused him or any of the brave victims of Parkland," she wrote. "For the record, I believe my show was the first to feature David immediately after that horrific shooting and even noted how 'poised' he was given the tragedy. As always he's welcome to return to the show anytime for a productive discussion."The mea culpa did little to quell backlash. Hogg told CNN on Friday that he was unimpressed with her apology and said it was likely prompted by the loss of ad dollars.As of Friday night, 14 companies — including the Rachael Ray-partnered dog food brand Nutrish, the travel site TripAdvisor, Office Depot and the streaming service Hulu — have said they will no longer advertise on Ingraham's show, according to a tally onMediaite.Last April, dozens of companies pulled away from the "The O'Reilly Factor" when allegations of sexual harassment against host Bill O'Reilly surfaced. He left the network shortly after. 2075

LAKELAND, Fla. -- A Florida bus attendant has been arrested for child abuse, according to the Polk County Sheriff's Office. Deputies say Brenda Nelson, 65, of Polk City has been charged with one count of child abuse for reportedly striking a special needs child on a school bus. On Wednesday, November 8 at about 4:23 p.m. the Transportation Safety Specialist told deputies a citizen complaint was received from a witness who reported she saw a bus attendant strike a female student on the head. The witness was not riding the bus. The witness advised officials that the incident took place on Wednesday, November 8 at approximately 3:58 p.m. The bus transports special needs children from the Doris Sanders Learning Center in Lakeland to their homes throughout Polk County, according to the Sheriff's Office. Deputies reviewed video footage that shows Nelson attempting to help a special needs child off of the bus. In the video, deputies say the victim was strapped to her seat by a "Houdini Harness" which is designed to significantly restrict her movement and mobility. At about 3:58 p.m., Brenda Nelson is seen on video walking by the victim and hitting her on the top of her head with an open left hand and saying "I'm gonna slap that tongue out of your mouth when I get up there."Two minutes later, the video shows Nelson walk behind the victim's seat, grab the victim by her hair and violently shake the victim's head back and forth and to the side, approximately four times. Deputies say after shaking the victim's head, Nelson was seen pulling something behind the victim's seat in an effort to tighten her harness. The victim attempted to reach behind her seat in the direction of Nelson and Nelson slapped the victim on the hand twice, according to the affidavit. According to the arrest affidavit, Nelson told the bus driver, Bradley Mckean, to take the victim home first, changing the regular bus route. Nelson was seen sitting next to the victim for the remainder of the bus ride and it appeared as if she was attempting to push the victim down into the seat to further limit her mobility. Deputies interviewed Nelson the following day. Nelson told deputies she did not remember hitting the victim on the head. She told deputies she was trying to get another child off the school bus and the victim kept on beating on the window and trying to get up out of her seat. Deputies did not observe the victim beating on the window of the school bus or acting in a disruptive manner as described by Nelson. Brenda stated, "I guess I done it. I didn't remember hitting her." Brenda also stated, "I must have just lost it. I don't remember doing that. I would never hit one of those kids."Brenda Nelson was arrested and transported to Polk County Jail.Due to the Veterans Day holiday, the Sheriff's Office does not have access to the video mentioned in the affidavit. The Polk County School Board released the following statement:  3005

Last year's seasonal flu vaccine effectiveness was just 42%, the US Centers for Disease Control and Prevention estimated. Even if vaccinated, then, people had inadequate protection against the flu.This limited effectiveness was due to a mutation that occurred in the influenza A (H3N2) vaccine strain, according to a new study published Monday in the journal Proceedings of the National Academy of Sciences. This vaccine mutation resulted from an egg-based manufacturing process commonly used today.This year's flu vaccine may also be imperfect, said Scott Hensley, author of the new study and an associate professor at the University of Pennsylvania. Add to that, he said, "this could end up being a pretty bad flu season."Still, he said, "our best protection" against severe illness is getting vaccinated with the flu shot we have today.Finding answersEach year before flu season begins, a vaccine is made based on whichever virus strains are expected to circulate. The selected seed strains are distributed to vaccine manufacturers which then produce their formulations and make them available to health care professionals before the season begins.During the 2015-16 season, vaccine effectiveness was 47%, while for the previous 2014-15 season, effectiveness was just 19%, according to the CDC. While the overall effectiveness of last season's vaccine was 42%, it was only 34% effective against the H3N2 viruses that dominated the season.Vaccine effectiveness varies based on how well it matches the circulating virus strains. Sometimes, a vaccine corresponds to the predominant virus yet its effectiveness is still not what scientists would expect. Trying to understand which element of the vaccine failed is difficult.Hensley and his team began their investigation of last year's vaccine by looking at the seed strains that had been distributed to vaccine manufacturers. These seed strains had been propagated in chicken eggs, the common method used today."The sequences of these viruses are available and when we did an alignment to see what the sequence of these vaccines were compared to the viruses that were circulating, it became very obvious that there was this mutation," said Hensley.To see the effects of the mutation, the team next looked at how the immune systems of both animals and humans who'd been inoculated with an egg-based flu vaccine responded to the actual circulating viruses.The antibodies -- immune system proteins that fight invading pathogens -- elicited in both animals and humans failed to bind to and neutralize the flu viruses, Hensley and his colleagues found.While most vaccines in the United States are made in chicken eggs, a small fraction are produced in insects or mammalian cells, Hensley explained. (These are given to people with egg allergies.) He and his team compared immune responses in animals and humans who had received a cell-based vaccine -- in this case, Flublok made by Protein Sciences Corporation."And we found both animals and humans receiving that (cell-based) vaccine had superior antibody responses that could bind and neutralize these circulating H3N2 strains," said Hensley.Making a better vaccine"Most of the infrastructure to produce vaccines in the US is based on chicken eggs," said Hensley. There are good reasons for this, including the fact that egg-based propagation allows manufacturers to quickly produce large quantities of vaccine.While egg adaptations have always been a problem, beginning last year it had become a "huge problem," said Hensley. "As soon as you try to grow this virus in eggs, within a few hours, the virus will acquire this kind of mutation."This is not an easy problem to fix, he said. To produce vaccines in cells means "a very expensive process for companies to just change their overall manufacturing process," Hensley explained. "You can't really do that on the drop of a dime."Meanwhile, the same seed strains used last year are being used this year to make the current vaccine, said Hensley."This year may be especially difficult because, in addition to this egg adaptive mutation which was present last year, there's indication that the H3N2 viruses are actually evolving," said Hensley.Not only will the vaccine be a mismatch with the actual circulating viruses due to egg adaptation but the vaccine could also be a mismatch due to unexpected viral evolution.What kind of flu season is ahead?It's too early to speculate which viruses will become dominant in the United States over the course of the coming flu season, said Hensley, "but it's starting to look like it will be H3 viruses." H3 viruses are influenza A viruses."There are the A group of viruses and the B groups," said Dr. William Schaffner, an infectious disease specialist at Vanderbilt University. "The A groups are the ones that usually are responsible for large epidemics ... whereas the B flu strains usually smolder along. They always cause illness -- it can be just as severe as the A strains -- but they don't produce large outbreaks."Though last year's vaccine was mostly ineffective in thwarting the flu, it still prevented nearly 30% of hospitalizations that might have resulted, according to CDC calculations. For older adults, that rate was even higher, at 37%. Plus, the vaccine reduced outpatient visits by 42% last season.The CDC advises everyone 6 months and older to get a flu shot, as only injectable flu vaccines are recommended. More than 130 million doses of flu vaccine have been distributed so far this year and flu activity is still low across the nation.It's still early days, but experts believe we may be facing a tough season, and not only because of vaccine concerns.The reason?Australia had a tough flu season this year, with a total of 215,280 laboratory-confirmed cases and 504 flu-associated deaths reported to its National Notifiable Diseases Surveillance System as of October 13, government data show. According to a surveillance system report, adults over the age of 80 and children between 5 and 9 years old have been most affected."In general, we get in our season what the Southern Hemisphere got in the season immediately preceding us," Dr. Anthony Fauci, director of the United States' National Institute of Allergy and Infectious Diseases, said in an interview last month.An "intelligent guess," therefore, is that the Northern Hemisphere, like the Southern Hemisphere, will likely battle more cases of the viral infection, he said, though "with influenza, it is never 100%.""If H3N2 viruses dominate the US flu season again this year, vaccine effectiveness will likely be moderate to low again," said Hensley.Still, he said, everyone should get their annual flu shot."The other components of the vaccine, like H1N1 and influenza B, will likely provide excellent protection," said Hensley. "The vaccine will also likely prevent severe disease and death caused by H3N2 viruses, even though this component of the vaccine is mismatched."  6969

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