山东强直性炎的治疗方法(济南强植性脊柱炎严重吗) (今日更新中)

SAN DIEGO (KGTV) - Like Pfizer, Moderna, AstraZeneca, and many others, INOVIO Pharmaceuticals has also raced to develop a COVID-19 vaccine this year.“We’ve been working really hard to move our vaccine through the stages of clinical testing. Some things have taken a little bit longer than we hoped. I think that’s kind of always the case when you’re trying to go at great light speed,” said Dr. Kate Broderick, INOVIO Pharmaceuticals Senior VP of Research & Development based in San Diego.Broderick said with funding from the U.S. Department of Defense, the biotech company started its Phase 2 clinical trial evaluating its DNA vaccine candidate, INO-4800.The first U.S. participants received a dose of the experimental vaccine earlier this month. Approximately 400 adults in the U.S. are expected to be enrolled in the trial by the end of the month.“We hope that in the early part of 2021, we’ll be going into a really large Phase 3 trial where we’re asking the question does our vaccine protect against the disease itself,” she said.Broderick said the company hopes to enroll about 6,000 participants initially in its Phase 3 trial once they get the green light to begin.A press release from the company last week stated that “The Phase 3 segment of the INNOVATE remains on partial clinical hold until INOVIO satisfactorily resolves the FDA’s remaining questions related to the CELLECTRA 2000 device that will be used to deliver INO-4800 into the cells of the skin.”Earlier data released from Pfizer and Moderna’s studies showing high vaccine efficacy was positive news for INOVIO.“We feel that we’re in a really good place. There’s eight billion people on the planet, and we’re certainly going to need quite a few different types of vaccines to ensure everybody is protected,” she said. “The Moderna and Pfizer vaccines are RNA vaccines; ours is DNA vaccine”Broderick said one significant benefit of INOVIO’S DNA vaccine candidate is it doesn’t have to be stored in low-temperature freezers, making it easier to ship out worldwide if approved.“In fact, we can keep it at room temperature, sitting on a desk somewhere for a year with no impact,” she said.INOVIO is projecting to have 100 million doses of its vaccine ready in 2021.“With these vaccines being approved, there is definitely an end in sight, but don’t let your guard down too fast,” she said. “Unfortunately, until everyone in the country gets vaccinated, we will still have to adhere to those kinds of annoying things, wearing masks, socially distancing. I know it’s frustrating, especially before the holidays, but just keep yourself safe and the people you love safe.” 2648

SAN DIEGO (KGTV) — Local research organizations and San Diego County are teaming with the CDC to expand the genome sequencing of COVID-19. That data gives county leaders important information to drive decision-making to help slow and control the spread of the virus.“The virus is constantly evolving and trying to figure out the best way to spread through our population. And is it does that, it changes a little bit,” said Dr. Louise Laurent a professor at UC San Diego, which is part of the team, along with Scripps Research.Laurent says that studying changes in the virus can help identify which cases are connected to each other and which are not. The county can use that information to understand what measures are working, where there are significant outbreaks, and whether new measures are needed to stop those outbreaks.The county’s top epidemiologist, Dr. Eric McDonald, tells ABC 10News that the data shows that through testing and contract tracing, efforts to control outbreaks have generally been effective. “It looks like many of the instances of individuals who are infected don’t result in too many other infections. We don’t have lots of big clusters of the same exact strain,” McDonald said.The data also shows that while the restrictions and actions taken by the county have been effective in controlling outbreaks, COVID-19 continues to spread in San Diego through travel. “What we found is that San Diego has been hit many different times and viruses from other places have come to San Diego,” Laurent said. “We don’t want to be an isolated place. We want to interact, right? We’re just that kind of place. It makes us vibrant. It makes us an interesting place to be. But that also makes us vulnerable.”The research team recently received a .5 million contract from the CDC to expand its work. 1823

SAN DIEGO (KGTV) — It's the final countdown for the San Diego Zoo's remaining panda bears.The zoo has launched a three-week farewell celebration for 27-year-old giant panda Bai Yun and her son, 6-year-old Xiao Liwu, before the two are repatriated to China this spring. A goodbye event held Saturday with zoo officials and Chinese Consul General Zhang Ping commemorated the end of the zoo's panda research program.RELATED:San Diego and giant pandas: A match made more than 30 years agoSan Diego Zoo to send pandas Bai Yun and Xiao Liwu to China, likely end panda exhibitThe zoo announced the program would end after more than two decades in partnership with China. No specific reason was given as to what led to the end of the partnership.The final day to see Bai Yun and Xiao Liwu will be April 29.San Diego Zoo Global Chief Operating Officer Shawn Dixon said at the time, “although we are sad to see these pandas go, we have great hopes for the future. Working with our colleagues in China, San Diego Zoo Global is ready to make a commitment for the next stage of our panda program.”Zoo visitors can see the pandas at their habitat leading up to their departure, and the park will be selling special commemorative bells and offering free tags to hang on the Giant Panda Friendship Wall.How you can see the giant pandasThe San Diego Zoo is open daily from 9 a.m. to 7 p.m. One-day passes for adults cost and for children ages 3-11. Multi-day visit passes are also available, starting at .60 for adults and .60 for children ages 3-11.Once inside the zoo, head over to Panda Canyon. To do so, hang a right on "Front Street" after entering the park and head toward Bieler Plaza. Take a left a the plaza and follow the road down to the panda exhibit. Or take the skytram over the exhibit, and double back over Bashor Bridge. A stairwell at the end of the bridge will lead to Panda Canyon below. Here's a handy PDF map of the zoo to check out before heading over.Morning panada tours are also offered for two hours daily, from 8:30 a.m. to 10:30 a.m. The tours start before the zoo opens, so guests can check out Bai Yun and Xiao Liwu enjoying breakfast and learn about them while up close. Tours start at 9. More information and tickets are available here.If you can't make it down to the zoo, the park has a giant panda camera feed running online daily.(The article has been updated to reflect the zoo's announcement to extend the panda exhibit by two days until April 29.) 2500

SAN DIEGO (KGTV) - It appears traffic along parts of Normal Street in Hillcrest will disappear for good, giving way to the Normal Street Promenade.City Councilmember Chris Ward says the city has signed on for the project as part of the Uptown Bikeways Project with SANDAG.The east side traffic lanes would stay but the lanes on the west side will be replaced by dedicated bike lanes and a pedestrian walkway along a two-block stretch from the Hillcrest Pride Flag to Lincoln Avenue."I'm excited.  Hillcrest is a close-knit community, and this will make it even more social," said Hillcrest resident Madison Layo."A great gathering space for everyone that people can rally around ... show a little pride," said Alex Craig, another Hillcrest resident.Ward says the public space can host events like the weekly farmer's market and Pride gatherings, along with events such as street fairs, movies and concerts.  The proposal also includes 70 extra parking spaces from Lincoln Avenue to Washington Street.  Supporters believe the project could also attract business activity to the area.The Uptown Community Parking District has allocated .8 million for the project.  Community outreach for the project will begin in early 2019 with construction expected to start in 2020. 1307

SAN DIEGO (KGTV) - It's been more than a month since the big ship fire in San Diego Bay.The flames are out but the boat is still there.It's become a sort of "morbid tourist attraction." Tourists and locals stopping to take photos of the charred Norton Sound bobbing up and down in the bay.RELATED: Multi-alarm fire erupts on fishing vessel docked in San Diego BayRestaurateur Melissa Moore was working just feet away when the ship mysteriously turned into a giant oven on Sept. 29. The smoke hung over Seaport Village sickening those nearby."As workers, we all started having headaches. We had to just leave," Moore recalled.Now it's early November and many are wondering why the boat is still parked in front of the Greek Islands Cafe - which Moore's family owns.RELATED: Questions remain after investigation into boat fire at San Diego HarborThe Port of San Diego told 10News they were working with the U.S. Coast Guard to move the ship as soon as possible. Contractors were disposing of chemicals on board.The Coast Guard cautioned there was no immediate leak or threat to the environment.Where did the ship come from?...10News learned the Norton Sound - which now has gaping holes in it - was originally owned by an American company in Seattle. It sailed into our bay in March.A San Diego shipping agent found it a place to dock. And then it was sold to a company in Mexico.Since the fire, a company employee has met with the Port and the Coast Guard at least once."I never did hear what was exactly in there," Moore said.No cargo was listed on the paperwork. San Diego Fire-Rescue said the cause of the fire was still under investigation, but there is currently no reason to suspect arson.So what now?...For now, the pier is locked off - which frustrates Moore."That is something people like to walk down," Moore said.RELATED: Mystery surrounds fishing boat that erupted in fire on San Diego BayStructural engineers must inspect it, according to the Coast Guard, and said the owner may not be able to afford to pay for the Norton Sound's removal.The Coast Guard is planning to use money from a special clean-up fund - paid for by a tax on oil refineries - to remove the ship. However, that may not happen for a few more weeks."The only positive thing is that people are still coming down here taking pictures.  (laughs)  other than that, they can take it away," Moore said. 2431

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