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WASHINGTON, May 11 (Xinhua) -- Researchers at Brigham and Women 's Hospital (BWH), a teaching affiliate of Harvard Medical School, have identified a human lung stem cell that is self-renewing and capable of forming and integrating multiple biological structures of the lung. This research will be published Thursday in the New England Journal of Medicine."This research describes, for the first time, a true human lung stem cell. The discovery of this stem cell has the potential to offer those who suffer from chronic lung diseases a totally novel treatment option by regenerating or repairing damaged areas of the lung," said the study's corresponding author Piero Anversa, who is also director of the Center for Regenerative Medicine at the hospital.Using lung tissue from surgical samples, researchers identified and isolated the human lung stem cell and tested the functionality of the stem cell both in vitro and in vivo. Once the stem cell was isolated, researchers demonstrated in vitro that the cell was capable of dividing both into new stem cells and also into cells that would grow into various types of lung tissue. Next, researchers injected the stem cell into mice with damaged lungs. The injected stem cells differentiated into new bronchioles, alveoli and pulmonary vessel cells which not only formed new lung tissue, but also integrated structurally to the existing lung tissue in the mice.The researchers define this cell as truly "stem" because it fulfills the three categories necessary to fall under stem cell categorization: first, the cell renews itself; second, it forms into many different types of lung cells; and third, it is transmissible, meaning that after a mouse was injected with the stem cells and responded by generating new tissue, researchers were then able to isolate the stem cell in the treated mouse, and use that cell in a new mouse with the same results."These are the critical first steps in developing clinical treatments for those with lung disease for which no therapies exist. Further research is needed, but we are excited about the impact this discovery could have on our ability to regenerate or recreate new lung tissues to replace damaged areas of the lungs," said Joseph Loscalzo, chair of the Department of Medicine at BWH and co-author.
FUZHOU, Feb. 5 (Xinhua) -- A minibus rolled over and fell into a reservoir in Shaowu City in southeast China's Fujian Province Friday afternoon, killing 10, local officials said early Saturday morning.Nine people were rescued, and two were still missing.The minibus bound for Shaowu from Yong'an lost control at 5:27 p.m. Friday when the driver apparently tried to avoid a motorbike. It fell into the Qianling Hydropower Station reservoir, according to officials with Nanping city government.About 200 police and rescuers were still looking for the missing people, and the investigation into the accident is underway.

BEIJING, March 8 (Xinhuanet) -- U.S. Food and Drug Administration (FDA) announced there was no new reason for safety concern in Pfizer Inc's Prevenar and Sanofi Aventis SA's ActHIBor vaccines, according to media reports Tuesday.Health agencies "have not detected new safety concerns or unusual reporting patterns" in the vaccines, which are used to prevent forms of meningitis and pneumonia, FDA spokeswoman Shelly Burgess said in an emailed statement.Health agencies in the United States will continue to monitor the vaccines for safety, the spokeswoman added.The Japanese health ministry had decided to suspend the vaccines after four unexplained deaths were reported. The causes of the deaths are still investigated, the Japanese ministry said in a release on its website.
SAN FRANCISCO, April 25 (Xinhua) -- Yahoo Inc. on Monday announced that it has acquired IntoNow, a startup company whose technology can let users almost instantly recognize TV content and share favorite programs with their friends.IntoNow has built a technology platform that can automatically identify live television content and any previously aired U.S.- based television programming in the past five years.It also offers an application for iPhone and other devices running Apple's iOS operating system, which can help users connect and engage with their friends around the shows they love.With the application, users can find out what their friends are watching and engage in discussion through their favorite social networks, or discover what shows they have in common with others and which of them are on air right now."Relying on social channels as a means for discovering content - - whether it's on a PC, mobile device, or TV -- is rapidly on the rise," Bill Shaughnessy, Yahoo's senior vice president of product management and product marketing, said in a statement."IntoNow's technology combines the ability to check-in to what a consumer is watching, engage in conversations, and find related content," he added.In a post on its company blog, Yahoo noted that the addition of IntoNow will enhance its video programming, and bolster its social engagement across the Yahoo network and on all screens.IntoNow, headquartered in Palo Alto in the U.S. state of California, was only launched in January 2011 and now has seven employees.Yahoo didn't disclose terms of the purchase. Technology blog TechCrunch reported that Yahoo paid between 20 million to 30 million U.S. dollars, citing sources with knowledge of the deal.
WASHINGTON, May 11 (Xinhua) -- Researchers at Brigham and Women 's Hospital (BWH), a teaching affiliate of Harvard Medical School, have identified a human lung stem cell that is self-renewing and capable of forming and integrating multiple biological structures of the lung. This research will be published Thursday in the New England Journal of Medicine."This research describes, for the first time, a true human lung stem cell. The discovery of this stem cell has the potential to offer those who suffer from chronic lung diseases a totally novel treatment option by regenerating or repairing damaged areas of the lung," said the study's corresponding author Piero Anversa, who is also director of the Center for Regenerative Medicine at the hospital.Using lung tissue from surgical samples, researchers identified and isolated the human lung stem cell and tested the functionality of the stem cell both in vitro and in vivo. Once the stem cell was isolated, researchers demonstrated in vitro that the cell was capable of dividing both into new stem cells and also into cells that would grow into various types of lung tissue. Next, researchers injected the stem cell into mice with damaged lungs. The injected stem cells differentiated into new bronchioles, alveoli and pulmonary vessel cells which not only formed new lung tissue, but also integrated structurally to the existing lung tissue in the mice.The researchers define this cell as truly "stem" because it fulfills the three categories necessary to fall under stem cell categorization: first, the cell renews itself; second, it forms into many different types of lung cells; and third, it is transmissible, meaning that after a mouse was injected with the stem cells and responded by generating new tissue, researchers were then able to isolate the stem cell in the treated mouse, and use that cell in a new mouse with the same results."These are the critical first steps in developing clinical treatments for those with lung disease for which no therapies exist. Further research is needed, but we are excited about the impact this discovery could have on our ability to regenerate or recreate new lung tissues to replace damaged areas of the lungs," said Joseph Loscalzo, chair of the Department of Medicine at BWH and co-author.
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