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WASHINGTON, May 20 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Friday approved Sutent to treat patients with progressive neuroendocrine cancerous tumors located in the pancreas that cannot be removed by surgery or that have spread to other parts of the body.Neuroendocrine tumors found in the pancreas are slow-growing and rare. It is estimated that there are fewer than 1,000 new cases in the United States each year.This is the second new approval by the FDA to treat patients with this disease. On May 5, the agency approved Afinitor."FDA believes it is important to provide cancer patients with as many treatment options as possible," said Richard Pazdur, director of the Office of Oncology Drug Products in the FDA's Center for Drug Evaluation and Research. "The agency is committed to working with companies to bring innovative new therapies to the market and encourages companies to continue exploring additional uses for approved products."The safety and effectiveness of Sutent was established in a single study of 171 patients with metastatic (late-stage) or locally advanced (disease that could not be removed with surgery) disease who received Sutent or a placebo (sugar pill). The study was designed to measure the length of time a patient lived before their disease spread or worsened (progression-free survival).Results from the study demonstrate that Sutent provided benefit to patients by prolonging the median length of time they lived without the cancer spreading or worsening to 10.2 months compared to 5.4 months for patients who received placebo.In patients treated with Sutent for neuroendocrine pancreatic tumors, the most commonly reported side effects included diarrhea, nausea, vomiting, fatigue, anorexia, high blood pressure, energy loss, stomach pain, changes in hair color, inflammation of the mouth, and a decrease in infection-fighting white blood cells.Sutent is marketed by New York City-based Pfizer.
LOS ANGELES, May 1 (Xinhua) -- Middle-aged adults who sleep too less or too much may be more likely to suffer cognitive decline, a new study suggests.According to the study, less than six hours of sleep each night is considered too little and more than eight hours as too much for middle-aged adults.The study, conducted by researchers at University College London Medical School, was published May 1 in the American medical journal Sleep.The researchers conducted the study in two periods -- the 1997- 1999 period and the 2003-2004 period. The participants were asked how many hours they slept on an average week night, and were asked the same question in 2003-2004 after an average 5.4 years of follow-up.The researchers compared those who reported changes in their sleep patterns with people whose sleep duration stayed the same over the course of the study.In the follow-up, each individual was given a battery of standard tests to assess his or her memory, reasoning, vocabulary, global cognitive status and verbal fluency.The study findings show that women who slept seven hours per night had the highest score for every cognitive measure, followed by those who had six hours of sleep. For men, cognitive function was similar for those who reported sleeping six, seven or eight hours.However, less than six hours of sleep -- or more than eight hours -- were associated with lower scores."Sleep provides the body with its daily need for physiological restitution and recovery," explained Jane Ferrie, a senior research fellow in the department of epidemiology and public health at the school. "While seven hours a night appears to be optimal for the majority of human beings, many people can function perfectly well on regular sleep of less or more hours."However, since most research has focused on the effects of sleep deprivation on biological systems, it is not yet fully understood why seven hours is optimal -- or why long sleeping appears to be detrimental, Ferrie said."Chronic short sleep produces hormones and chemicals in the body which increase the risk of developing heart disease and strokes, and other conditions like high blood pressure and cholesterol, diabetes and obesity," she added.

BEIJING, Feb. 14 (Xinhua) -- "Dear Premier Wen, I'd like to tell you the good news first. The problem I brought up at the seminar last year has been solved in Beijing," wrote 34-year-old, wheelchair-bound Li Nan to Chinese Premier Wen Jiabao on Jan. 20 this year.The problem Li referred to was the high prices of one-off hygiene products that had plagued people with work-related spinal cord injuries for a long time.On Jan. 31, 2010, Wen talked with a group of ordinary people in Chaoyang District in Beijing to get their opinions on the draft of a government work report that will be submitted to the national legislature in March.Wen asked Li to be the first to voice her views at the seminar. Li said that patients with spinal cord injuries had to spend about 2,000 yuan (303 U.S. dollars) a month on one-off hygiene products because of their incontinence."My injury allowance is roughly 2,000 yuan a month. I have to live on my parents' pension," she said.She suggested giving more attention to the employment and mental health of the disabled, and also for some revisions on the catalogue of drug and auxiliary devices for those disabled by work-related injuries. She also proposed more subsidies for these people.Responding to the suggestions, Wen said, "Li Nan's case is far from an individual one. The disabled are a very large group of people in China who need more attention... We need to study, revise and renew the government regulations on work-related injury insurance."Wen also encouraged Li to be optimistic in face of ordeals.Li, who graduated from Beijing Youth Politics College in 1997, was once a prize-winning amateur dancer. However, she became confined to a wheelchair after a traffic accident in 2003.On March 5 last year, Li beamed with pride as she watched TV. Premier Wen was delivering the government work report at the annual session of the national legislature.Wen pledged to "work harder to build the social security and social services system for people with disabilities." The premier also promised that "Workers' compensation will be extended to all of the 1.3 million workers injured in previous jobs who are not receiving benefits.""I am thrilled to see that my advice on improving social security for the disabled was included in the government work report," Li said in her letter, which summarized the changes she experienced in the past year because of the improved social security system.The Beijing Municipal Human Resources and Social Security Bureau announced last year that people would be reimbursed for one-off diapers and urine bags under the municipal work-related injury insurance program beginning June 2010."The Beijing policy has relieved our heavy economic burdens and ensured the quality of our life," Li wrote.Li, however, said that though some places has begun to give living and nursing subsidies for the disabled, the policy needs to be extended to other parts of the country.After reading the letter on Jan. 31, Wen Jiabao instructed relevant organs in the State Council, or Cabinet, and the Beijing municipal government "to conduct research and set down policies to better protect and aid people with serious disabilities, and to help them solve their difficulties and improve their quality of life."
WASHINGTON, May 11 (Xinhua) -- NASA's Dawn spacecraft has obtained its first image of the giant asteroid Vesta, which will help fine-tune navigation during its approach, the U.S. space agency announced Wednesday.Dawn expects to achieve orbit around Vesta on July 16, when the asteroid is about 117 million miles from Earth.The image from Dawn's framing cameras was taken on May 3 when the spacecraft began its approach and was approximately 752,000 miles (1.21 million km) from Vesta. The asteroid appears as a small, bright pearl against a background of stars. Vesta also is known as a protoplanet, because it is a large body that almost formed into a planet."After plying the seas of space for more than a billion miles, the Dawn team finally spotted its target," said Carol Raymond, Dawn's deputy principal investigator at NASA's Jet Propulsion Laboratory in Pasadena, California. "This first image hints of detailed portraits to come from Dawn's upcoming visit."Vesta is 330 miles (530 km) in diameter and the second most massive object in the asteroid belt. Ground- and space-based telescopes obtained images of the bright orb for about two centuries, but with little surface detail.Mission managers expect Vesta's gravity to capture Dawn in orbit on July 16. To enter orbit, Dawn must match the asteroid's path around the sun, which requires very precise knowledge of the body's location and speed. By analyzing where Vesta appears relative to stars in framing camera images, navigators will pin down its location and enable engineers to refine the spacecraft's trajectory.Dawn will start collecting science data in early August at an altitude of approximately 1,700 miles (2,700 km) above the asteroid's surface. As the spacecraft gets closer, it will snap multi-angle images allowing scientists to produce topographic maps. Dawn will later orbit at approximately 120 miles (200 km) to perform other measurements and obtain closer shots of parts of the surface. Dawn will remain in orbit around Vesta for one year. After another long cruise phase, Dawn will arrive in 2015 at its second destination, Ceres, an even more massive body in the asteroid belt.Gathering information about these two icons of the asteroid belt will help scientists unlock the secrets of our solar system's early history. The mission will compare and contrast the two giant asteroids shaped by different forces. Dawn's science instruments will measure surface composition, topography and texture. Dawn also will measure the tug of gravity from Vesta and Ceres to learn more about their internal structures. The spacecraft's full odyssey will take it on a 3-billion-mile (5-billion-km) journey, which began with its launch in September 2007.
BEIJING, Feb. 22 (Xinhua) -- Chinese Foreign Minster Yang Jiechi and his Austrian counterpart Michael Spindelegger held talks here on Tuesday, pledging to enhance bilateral ties through deeper cooperation.Yang hailed the remarkable development of bilateral ties since the two countries established diplomatic relations 40 years ago.He said both sides should see the 40th anniversary as a new starting point for maintaining traditional friendship, deepening political mutual trust, expanding cooperation and enhancing cultural exchanges, to strive for greater development of bilateral ties.He stressed that China appreciates the Austrian government's adherence to the one-China policy.For his part, Spindelegger said the Austrian side attaches great importance to developing ties with China and he hoped both sides will strengthen cooperation in various fields in a more pragmatic way.The two also exchanged views on some international and regional issues of common concern.
来源:资阳报