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San Francisco is on course to become the first US city to effectively ban the sale of e-cigarettes once its board of supervisors votes on Tuesday.The board is expected to pass an 191

Stocks sank again on Wall Street as more signs piled up of the economic and physical pain being caused by the coronavirus outbreak. The S&P 500 and Dow Jones Industrial Average dropped nearly 5% in afternoon trading on Wednesday after President Donald Trump warned the country to brace for “one of the roughest two or three weeks we’ve ever had in our country.” The selling was widespread, and all 11 sectors that make up the S&P 500 were down. Treasury yields sank as investors moved into safer investments. Stocks worldwide fell following a weak reading on Japanese business sentiment and after big British banks cut their dividends to preserve cash. The Dow Jones Industrial Average lost nearly 1,000 points, which means the index has lost nearly 9,000 points in the last eight weeks. 808

So the NBA's inviting 22 teams to Orlando: 13 Western Conference, 9 Eastern Conference. Eight-regular season games per team. Play-in for the 8th seeds. July 31-October 12. Vote tomorrow to ratify. The NBA's back.— Adrian Wojnarowski (@wojespn) June 3, 2020 269

STATEN ISLAND, N.Y. — Parents desperate to get their children with dyslexia the daily instruction they needed went out on their own to solve the problem. These changemakers, along with advocates and elected leaders, helped to create a 247

Strong opioid dosage is the topic of a two-day public hearing by the Food and Drug Administration — which is trying to discern the benefits and risks.For Katrina King, her opioid addiction began with a back injury. It got so bad she spent two years behind bars after getting caught with forged prescriptions. King blames being put on high-dose medication too strong for her injury."The extended release — introducing that into the picture as such a potent dose so early in my diagnosis without trying anything else — ended up being catastrophic," she said.Some people have suggested the FDA remove high-dose opioids form the market to fight the deadly epidemic. Others argue the stronger meds are necessary to manage pain for some patients and getting rid of it could worsen pain for those people, leading to potential suicides."We don't want to cause additional suffering for people who have unmanageable pain that does make them feel they don't want to live anymore. On the other side of that, I would challenge the pharmaceutical industry and the FDA to come up with other methods of pain control," King said.The FDA will review public comments and decide whether to make change, which could include tougher regulations on reducing the use of high-dose opioids. 1276