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WASHINGTON, Jan. 19 (Xinhua) -- New research published this week in Nature Medicine indicates that targeted drugs such as gefitinib might more effectively treat non-small cell lung cancer if they could be combined with agents that block certain microRNAs.The study, led by investigators with the Ohio State University Comprehensive Cancer Center, shows that overexpression of two genes called MET and EGFR causes the deregulation of six microRNAs, and that this deregulation leads to gefitinib resistance.The findings support the development of agents that restore the levels of these microRNAs. It offers a new strategy for treating non-small cell lung cancer, which is responsible for about 85 percent of the 221,000 lung-cancer cases and 157,000 deaths that occur annually in the United States. It also suggests that measuring the expression levels of certain microRNAs -- those controlled by the MET gene -- might predict which lung-cancer cases are likely to be resistant to gefitinib.Epidermal growth factor receptor (EGFR) is frequently overexpressed in non-small cell lung cancer, and this leads to uncontrolled cell proliferation. Gefitinib selectively inhibits EGFR activation and triggers cancer cells to self-destruct by apoptosis. However, non-small cell lung cancer cells inevitably develop resistance to the drug. The study reveals how this resistance occurs."Our findings suggest that gefitinib resistance that is caused by MET overexpression is at least partly due to miRNA deregulation, " says principal investigator Carlo Croce.

TAIYUAN, Jan. 9 (Xinhua) -- China successfully launched the Ziyuan III satellite Monday from the Taiyuan Satellite Launch Center in northern Shanxi province.The satellite, a high-resolution remote-sensing satellite for civilian use, was launched at 11:17 a.m. aboard a Long March 4B rocket, according to a statement from the center.The satellite, weighing 2650 kg, entered an orbit of 500 km above the Earth about 12 minutes after it was launched. It has a designed life expectancy of five years.According to the center, the satellite is tasked with offering services to aid the country's land-resources surveys, natural-disaster prevention, agriculture development, water-resources management, and urban planning.The rocket also carried a satellite from Luxemburg, according to the launch center.The orbiter was developed and produced by the China Academy of Space Technology, a subsidiary of China Aerospace Science and Technology Corporation (CASC).The Long March 4B rocket is developed by Shanghai Academy of Spaceflight Technology, another CASC subsidiary. Monday's mission marked the 156th flight of China's Long March series of carrier rockets.

BEIJING, Sept. 30 (Xinhuanet) -- Tobacco companies concealed the knowledge of radioactive substance in cigarettes from public for over four decades, a new study revealed.The revelation was made by a research team from the University of California, Los Angeles, published on Thursday in the online edition of the U.S. medical journal Nicotine and Tobacco Research.The researchers analyzed 27 timeworn documents and discovered that tobacco companies had knew the existence of polonium-210, a hazardous radioactive substance, in the tobacco since 1959.The companies studied polonium-210 throughout the 1960s, and concealed their findings about the carcinogenic potential of the radioactive substance.Hrayr Karagueuzian, the study's lead author, said the tobacco companies' deception surprised him.According to the revelation, the companies had knew the "cancerous growths" in the lungs of smokers, and even calculated how much radiation a regular smoker would inhale over 20 years.Karagueuzian and his team conducted again the study recorded in the tobacco documents and found that the radiation in cigarettes would cause up to 138 deaths for every 1,000 smokers over a period of 25 years.However, tobacco manufacturer denied that they had concealed the facts from the public.David Sutton, spokesman of Philip Morris, the largest U.S. tobacco company, said the polonium-210 was a "naturally occurring element in the air" and had been widely discussed by the public health community for years.

BEIJING, Jan. 6 (Xinhua) -- Surveillance data on the size and frequency of earthquakes in Antarctica collected by China's Great Wall Station show that the continent is not earthquake-free, a Chinese seismic expert said Thursday."China's newly-built seismic observatory in Great Wall Station has documented a hundred-odd earthquakes occurring in the region over the past year," said Chang Lijun, a member of China's 28th Antarctic expedition team.The discovery challenges the prevailing notion that the Antarctic has no earthquakes, as many earthquakes have gone undetected due to lack of seismological observation in the region.However, thanks to technological advances, scientists have discovered that the continent is still subject to some minor tremors.Chang, also an associate researcher at China Earthquake Administration's Geophysics Institute, said last year's earthquakes ranged in magnitude from 0.5 to 4, scales which are usually undetectable to common people.The tectonic movements of Antarctica, which sits on two plates that pulled away from each other in the northern Ross Sea between 28 and 40 million years ago, but later converged, fascinate geologists worldwide.At the end of 2010, Chinese scientists set up a new broadband seismic observatory in Great Wall Station, greatly increasing China's ability to measure tremors and tectonic movements on the continent.

BEIJING, Dec. 12 (Xinhua) -- A Foreign Ministry spokesman said on Monday that China welcomes the EU's new measures for coping with the European sovereign debt crisis worked out at the recently-concluded EU summit."We hope relevant measures can help stabilize the market, boost confidence in the market, stop the crisis from worsening, promote employment and economic growth, and push forward European integration," Foreign Ministry Spokesman Liu Weimin said at a routine press briefing.Last Friday at the summit in Brussels, EU leaders agreed on establishing a new "fiscal compact" based on inter-governmental treaties rather than the expected EU treaty changes. Britain opted out of the compact.Under the fiscal compact, member states will have to submit their draft budgetary plans to the European Commission, the EU's executive arm.As world's largest economy, the stable and healthy growth of the European Union and the Eurozone will be crucial to maintaining the momentum of recovery in the world economy, Liu said.China will maintain its support for EU integration, and continue to back the EU's efforts in combating the debt crisis in various ways, so as to jointly promote the stability of the international financial market and the recovery and growth of the world economy, he said."We are confident in Europe and the Eurozone, and believe that the EU has the ability and wisdom to resolve the sovereign debt crisis," Liu said.

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