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WASHINGTON, April 25 (Xinhua) -- A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.Working in cell lines from colorectal cancer patients, researchers found that the class of drugs called PARP inhibitors worked against tumors with mutations in the MRE11 gene.About 15 percent of all colorectal cancers have what's called microsatellite instability, a type of error in the DNA. About 82 percent of those tumors have the MRE11 gene mutation."This is a potential broader application for PARP inhibitors, beyond breast and ovarian cancer. This is a class of drug that's already shown safety in early clinical trials and now might benefit some colorectal cancer patients as well," says lead study author Eduardo Vilar-Sanchez, a hematology/oncology fellow at the university, in a statement.The study, which was published Monday in Cancer Research, also found that PARP inhibitors are even more effective when both copies of MRE11 were mutated. Each person carries two copies of each gene, which means mutations can occur in either one or both copies. The researchers suggest that PARP inhibitors could be targeted specifically to colorectal cancer patients who have two copies of the mutated gene.Researchers are planning a phase I clinical trial to look at using PARP inhibitors in colorectal cancer patients with two mutated copies of MRE11. Future trials are being considered using PARP inhibitors to prevent colorectal cancer and other cancers in people with Lynch syndrome whose tumors have this mutation.Microsatellite instability is also seen in prostate cancer and endometrial cancer, suggesting potential for PARP inhibitors to play a role in additional types of cancer as well, Vilar-Sanchez says, adding that more research is needed in these areas.

BEIJING, May 24 (Xinhuanet) -- CT scan, a widely used heart-imaging test, is likely to result in the over treatment for patients with heart disease, according to a study published online by the Archives of Internal Medicine on Monday.CT, which produces a detailed image of the heart that reveals cholesterol buildups in the coronary arteries, is widely used in the hospital around the world."Testing might lead to more harm than good," said McEvoy, a doctor at Seoul National University Bundang Hospital in S. Korea.His team led the study, in which 2,000 healthy adults were divided into two groups. One thousand adults had CT scans and another half had standard tests, including routine checks of their blood pressure and cholesterol levels.After 18 months, the 215 people who had worrisome CT scans were advised to have additional tests and medical treatment, and some even advised to have surgery. But less than 10 percent in the group of standard test were reported to need medications.Therefore, physicians cannot easily ignore the diagnoses made by the new imaging techniques, McEvoy said, "We are left with the dilemma of what to do with the results,"According to McEvoy, doctors should focus on patients' lifestyle and traditional risk factors such as smoking and obesity.

BEIJING, Jan. 30 (Xinhua) -- A total of 248 people were arrested in China last year for involvement in food safety cases, food safety authorities said Sunday.The country dealt with 130,000 cases involving food safety last year, including 115 criminal cases, according to a statement of the National Food Safety Regulating Work Office.The cases touched upon such areas as production of edible agricultural produce, food production, food circulation, catering services and food exports and imports,"No major incident occurred last year, and the overall food safety situation maintained stable," said the statement.Last year also saw a nationwide crackdown on "gutter oil", usually made from discarded kitchen waste that has been refined, after media reports that it was commonly used by small restaurants.Since July when the State Council, or Cabinet, ordered the eradication of "gutter oil", 165.7 tons of edible oil has been confirmed to have been disqualified and produced by unknown sources.Chinese authorities since July last year have also cracked down on the use of undisposed tainted milk powder produced before the melamine scandal of 2008.About 2,132 tonnes of melamine-tainted milk powder was seized in the latest crackdown, the statement said.A total of 191 officials were punished for failing to do their duty in food safety enforcement, with 26 of them fired, it said.In July last year, Dongyuan milk powder, produced in west China's Qinghai Province, was found to contain excessive levels of melamine, a toxic chemical normally used in the manufacturing of plastics, which triggered the nationwide crackdown.It is the latest blitz on tainted milk products since 2008 when melamine-tainted milk powder killed at least six infants and sickened 300,000 children across the country.

BEIJING, Feb. 24 (Xinhua) -- Chinese Premier Wen Jiabao attended the opening ceremony of the China-EU Year of Youth in Beijing on Wednesday, encouraging young people from China and the EU to build a brighter future for bilateral strategic partnerships.Joining over 500 young people from China and the EU in the Capital Museum in downtown Beijing, Wen said that the year-long youth exchange campaign was the first theme year between China and the EU since the establishment of diplomatic ties, and is also the largest-ever China-EU cultural exchange program."This has revealed that our relations will be more vibrant in the future and full of hopes," he added.China and the EU are in a vital period for deepening cooperation, Wen said, calling on young people from both sides to consider and explore ways to share opportunities, meet challenges and seek common development, which has benefits for China, the EU and the world.Wen hopes that young people from both sides would always be brave in pursuing innovation and the truth. He also encouraged them to learn from each other in a frank and open spirit, in a bid to jointly create a better future for China-EU ties.A video speech from European Commission President Jose Manuel Barosso was aired at the ceremony. He said that the Year of Youth offers an interactive platform for European and Chinese young people to enhance mutual understanding and friendship and also inject vitality to China-EU relations.Premier Wen and Barroso jointly initiated The China-EU Year of Youth during the 12th EU-China summit held in 2009.Along with the opening ceremony in Beijing, Chinese and European youth were immersed in two-day discussions on topics such as culture, education, volunteering, creativity and environmental protection starting on Tuesday."We had excellent discussions on possible cooperation projects, ranging from environmental protection, world heritage to art and intellectual property," said Pierre Arlaud, a member of an EU youth delegation that arrived in Beijing on Monday to participate in the opening ceremony."I can feel there is a strong will from both sides to deepen understanding and forge a stronger partnership," he added.The opening ceremony was the first in a series of exchange activities that will be held throughout the year in China and Europe. The events include cultural seminars, volunteer service conferences, youth summer camps and TV debates.The year-long program was co-hosted by the All-China Youth Federation and the European Commission. The initiative aims to promote intercultural dialogue and strengthen mutual understanding and friendship between young people in China and the EU, as well as encouraging them to support the development of China-EU relations.

WASHINGTON, Jan. 19 (Xinhua) -- China and the United States have agreed to further boost their bilateral relationship toward a cooperative partnership for the benefit of the whole world, President Hu Jintao said Wednesday.The visiting Chinese leader presented the course forward at a joint press conference at the White House with his U.S. counterpart Barack Obama following their eighth meeting in two years.During the talks, conducted in "a candid, pragmatic and constructive atmosphere," the two sides reached "important agreement on China-U.S. relations and major international and regional issues of shared interests," according to the Chinese president.Chinese President Hu Jintao (2nd L) holds a bilateral meeting with U.S. President Barack Obama (2nd R) at the White House in Washington, the United States, Jan. 19, 2011. "We both agree to further push forward the positive, cooperative and comprehensive China-U.S. relationship," Hu said, adding that both sides also pledged to forge "a China-U.S. cooperative partnership based on mutual respect and mutual benefit" for the benefit of the two countries and beyond.Meanwhile, the two sides "should firmly adhere to the right direction," respecting each other's core interests and handling their relations with a long-term perspective, which will enable both countries to make greater contributions to world peace and development, he said.Citing the growing number of global challenges, the Chinese president stressed that Beijing and Washington "share expanding common interests and shoulder increasing common responsibilities."Accordingly, he added, the two sides have agreed to strengthen exchanges and cooperation in economy, trade, environment, education, science and technology, non-proliferation and counter-terrorism among many other fields.During Hu's ongoing state visit, the two countries signed a number of cooperation agreements. "These will inject fresh momentum into our bilateral cooperation and create a great many job opportunities for our two countries," Hu said.He added that he and Obama also discussed some disagreements in the economic and trade area, with both sides pledging "to continue to appropriately resolve these according to the principle of mutual respect and consultation on an equal footing."Commenting on the relations between the countries's armed forces, Hu said, "We believe expansion of military exchanges and cooperation will be conducive to deepening mutual trust between our two countries."On the situation on the Korean Peninsula, he said that both countries agreed to work together with relevant parties to maintain peace and stability on the peninsula, promote denuclearization of the peninsula and achieve lasting peace and security in Northeast Asia.The Chinese leader reaffirmed China's firm commitment to the path of peaceful development and a win-win strategy of opening up, and appreciated Obama's commitment to a positive and constructive China policy."China is a friend and partner of all countries, and China's development is an opportunity for the world," he said.

来源：资阳报