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SAN DIEGO (KGTV) — Legoland debuted a new land for youngsters as well as a train attraction for park guests Thursday.Park officials welcomed in the addition of Duplo Playtown and a new mini-locomotive in a ribbon cutting with families from Ronald McDonald House Charities. A special check presentation of ,000 was also made to Ronald McDonald House. The park says the new Duplo Playtown will give guests the best views of Miniland U.S.A. from high atop the theme park. The land is geared for kids five and under and features ten interactive areas with sounds and games to entertain.The new mini-locomotive, the Legoland Express, was also unveiled. The ride will sit at the edge of Fun Town, perfect for children to experience their first theme park ride and views of the park. 787

SAN DIEGO (KGTV) — It’s one of the few drugs shown to help fight the novel coronavirus, and a large federal study on remdesivir just entered a new phase.Previous research sponsored by the National Institute for Allergy and Infectious Disease showed remdesivir shortened recovery time in hospitalized COVID-19 patients on average from 15 days to 11 days.Now scientists and doctors are racing to find the perfect cocktail against COVD-19 by blending remdesivir with other drugs.California-based Gilead Sciences originally developed the drug to fight Ebola, but remdesivir was never approved. Gilead Sciences has offices in Oceanside.The drug works by interrupting the virus’ ability to replicate.“Remdesivir acts by shutting down virus production,” said Dr. Peter Chin-Hong, an infectious disease expert at University of California San Francisco. “It just forces the virus to stop making virus children.”Dr. Chin-Hong is studying remdesivir as part of the NIAID research.The problem is that stopping the virus from replicating isn’t enough for some severely ill patients. They suffer from a second problem: massive inflammation from the immune system’s war with the virus.That’s why scientists are trying a cocktail approach.“You have the virus to take care of, but you also have the body's response to the virus, which is inflammation, that you also have to take care of,” said Dr. Chin-Hong.Researchers started testing the first drug cocktail in May, using an arthritis drug called baricitinib that tames inflammation.But as the data on that part of the study gets crunched, researchers began testing the second cocktail this month, a combination of remdesivir and interferon beta.“Interferon beta is something we produce naturally to fight viruses,” said Dr. Chin-Hong. He said studies have shown people who don’t produce enough interferon beta struggle to fight off the virus.Researchers selected interferon beta after two small studies showed promising results against the coronavirus.Interferon beta can both reduce inflammation and kill viruses, so doctors are hoping it will be a potent one-two punch with remdesivir.Dr. Chin-Hong said he and other researchers started administering the new cocktail this month.Some patients will receive the cocktail, some will receive a placebo, and some will get remdesivir only. This kind of clinical trial is called an adaptive trial, which the FDA started encouraging in 2004. After each phase, the winning drug or cocktail will be tested against a new challenger.Dr. Chin-Hong said the eventual cocktail may include three or more drugs, similar to HIV medication. 2617

SAN DIEGO (KGTV) -- Kevin Luo of Pacific Trails Middle School is getting ready for his trip to Washington D.C. to compete in the Scripps National Spelling Bee.Luo, who is a student at Pacific Trails Middle School, was crowned the winner of the countywide spelling bee in March. Last year's winner, Yash Hande, was also a student at Pacific Trails. Luo said in an interview with 10News that the Hande is helping him prepare for the national Bee.RELATED: Pacific Trails Middle School student crowned winner of countywide spelling bee  Luo also expressed that he is a little nervous to be on the national stage. “It’s probably going to be really intense for the first few days but after that, it will be relaxed.”The Scripps National Spelling Bee will take place May 29-31 in Washington, D.C. 832

SAN DIEGO (KGTV) — Mark your calendars, Padres fans. The team is giving its first look at next year's new brown uniforms this fall.The Padres are set to debut their new 2020 uniforms at an event on Nov. 9 at Petco Park, a team spokesperson confirmed to 10News. The news originally dropped after President of Business Operations Erik Greupner revealed the date on Twitch.Since January, fans have waited in anticipation of seeing the new brown uniforms after the team announced the color change. The team had until May to submit their final proposal for the new threads the Friars will wear.RELATED: San Diego Padres introduce Jayce Tingler as new managerPadres' Yates wins Baseball Digest's top reliever awardFocus group testing was held, giving select fans a peak at variations featuring brown and gold combinations. The Padres haven't released a sample of the uniform yet though.The change comes as Nike inked a 10-year deal to be the MLB's official uniform and footwear supplier starting in 2020. Some form of brown and mustard was used in Padres' jerseys until 1984. The inclusion of brown was abandoned after the 1990 season when the team took on a blue and orange color scheme. Brown only began making its way back into the Padres' uniforms in 2016, when the team featured it as throwback uniforms for select games.But the hope now for many fans: New Padres threads, young talent, and a world championship on the horizon. 1434

SAN DIEGO (KGTV) - It's been months since construction began on eight prototypes for a wall to span the U.S.-Mexico divide. The structures, built by six companies that have largely remained out of the spotlight, faced a barrage of tests by border officials, reportedly including jackhammers, saws, torches and other tools and climbing devices to try and thwart the walls.The contractors tasked with building the prototypes were: 456