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Holidays will look different this year for many Americans, with dinners outside, social distancing, or passing on family gatherings altogether. But several companies developing rapid at-home COVID-19 tests are hopeful that won't be the case next year. The goal is to make inexpensive, easy-to-use COVID tests that can deliver results in minutes, just like a pregnancy test. "For people to feel comfortable to associate with friends or family, there needs to be a testing methodology ideally that can be performed at home," said Tony Lemmo, CEO of the manufacturing company BioDot.The company's technology is being used by over 70 manufacturers worldwide making COVID-19 antigen, antibody, and PCR tests. Their automated platforms dispense nanoliter/picoliter amounts of reagent onto the tests accurately and fast.Lemmo says just one of their systems can support the production of roughly 100 million COVID-19 tests per year, helping to make high-volume production possible.“We knew we were going to be called on by customers to manufacture more equipment to provide them the ability to manufacture more tests," said Lemmo. To meet customer demand, BioDot increased staffing and built a new facility, compressing production time from months to weeks. The FDA recently authorized the first rapid at-home test that can deliver results in 30 minutes, eliminating the need for a lab to test the sample. But the molecular single-use test will only be available to patients with a doctor's prescription who are suspected of being infected with COVID-19.Companies developing tests hope the FDA will soon authorize another at-home testing tool: the rapid antigen test.These inexpensive tests provide results within minutes, and companies developing them say millions could be sold without a doctor's referral.“From what we’re hearing, it’s really just a matter of possibly months before there’s at least sufficient data to be able to support an at-home use of a test like an antigen test," said Lemmo.Lemmo says if authorized by the FDA, manufacturers could make millions of these tests in a matter of months. But antigen tests are less accurate, and the FDA wants to ensure they'll be simple enough for people to use at home. There are also concerns over how the data will be reported to health authorities. “I think any at-home testing or massive rollout of a test into the communities needs to be done very carefully and with a lot of education around it," said Clinical Lab Director Melissa Miller. Dr. Miller is a professor of pathology and laboratory medicine at the University of North Carolina Chapel Hill and Medical Director for the Clinical Microbiology Lab for the Medical Center.She worries the inaccuracies of these tests could eventually lead the public to lose trust in all testing. “Even at 98 percent specificity, which is very, very high. That means you’re going to have a false positive two out of every 100. If you started testing a hundred million people, this is millions of people who have a false-positive test," said Dr. Miller. She says this could lead to healthy people isolating and missing work or school unnecessarily, and false-negative results could give people a false sense of security. “These rapid antigen tests were pushed out to skilled nursing facilities; this is a very high-risk patient population. This is actually where you want a very accurate test," said Dr. Miller. She says it’s unclear how well antigen tests detect the virus in asymptomatic patients but agrees more data is needed to figure that out.“It might make more sense for K-12 schools, or even college settings, where there’s less risk for a poor outcome if you have a false positive or a false negative," said Dr. Miller. But with a growing demand for convenient at-home testing, manufacturers are hopeful that in the months ahead, the FDA will soon open the door to new solutions. 3889

Hours after Amazon instructed its employees to remove the short-video sharing app TikTok from their devices -- the company back stepped.The online retail giant says the email was sent in error and there is no change to amazon's policy regarding TikTok.In the email sent to employees Friday morning and obtained by CNN, Amazon said that due to "security risks, the TikTok app is no longer permitted on mobile devices that can access Amazon email."A TikTok spokesperson said Amazon "did not communicate to us before sending their email, and we still do not understand their concerns."Politicians say the app could undermine national security given its ties to China.Cybersecurity experts have been more cautious about that assessment.TikTok is owned by the world's most valuable startup, a Chinese company named Bytedance. 828

HAVRE DE GRACE, Md. — Frankie Reeling’s life was reeling. A year ago, he was not expected to make it out of emergency colon surgery. But Frankie fooled us.Now he is messing with us, with his funny bones. Every night, you will see the Bone family. There is Sally, Ooogie Boogie and Jack.Frankie said we are so trapped in fear during the coronavirus pandemic, that on his favorite holiday, Halloween, he would make sure we were howling our funny bone off.He comes up with a theme every night. Then runs to a thrift store for the items he needs and dresses up his front lawn.This story originally reported by Jamie Costello on WMAR2News.com. 647

Here are this week's hottest home video releases:CocoExploring Mexican culture through the lends of the Dia de Los Muertos tradition, the film tells a heart-melting tale about a music-loving boy who uncovers family secrets while exploring the realm of the dead. Superb visuals meld with a tear-jerking script to create a watershed experience. The Disney/Pixar For my full review, click here. Extras include deleted scenes, filmmaker commentary, drawing lessons and a slew of background featurettes.Doctor Who: The Complete Peter Capaldi YearsA compilation of three seasons starring fan favorite Peter Capaldi -- the 12th actor to take on the iconic role -- pulls together seasons eight through 10 of the show, adding previously unreleased deleted scenes to the existing slate of extras. "Doctor Who" fans should also take note that the Christmas special "Doctor Who: Twice Upon a Time" is also available.Lady and the Tramp Walt Disney Signature CollectionThe 1955 Disney classic gets the full-featured Blu-ray and digital release in a set loaded with extras. The delightful romance, which boasts the memorable spaghetti kiss scene, holds up well, continuing to cast its spell more than a half-century after release. A sing-along mode, reenactments of Walt Disney's meetings with animators, deleted scenes and peeks inside Disney's home life fill out the slate of special features. Murder on the Orient ExpressThe latest film adaptation of the 1934 Agatha Christie murder mystery rounds up Johnny Depp, Kenneth Branagh, Michelle Pfeiffer, Penelope Cruz, Judi Dench, Daisy Ridley and Leslie Odom Jr. for the classic whodunnit. Branagh directs with his typical panache, keeping the story vital and relevant for modern audiences while maintaining loyalty to the past. For my full review, click here. Extras include deleted scenes, filmmaker commentary and featurettes on Christie, the effects and the music.Studios provided review screeners. 1980

Harvey Weinstein, Matt Lauer, Kevin Spacey are among a list celebrities and politicians, who all faced quick and intense backlash from sexual harassment allegations.The scandals sparked the #MeToo movement. Now, a year later, some feel the movement has shifted.“Certainly, after the #MeToo movement, what we have seen [is] survivors have more safe spaces to go to, to access support,” says Bridgette Stumpf, a sexual assault advocate with the Network for Victim Recovery of D.C. “Unfortunately, with the Times survey just over a month ago, that said of women surveyed 60 percent say their environment of reporting sexual harassment assault doesn’t feel any different than a year ago.”Decades-old allegations threatened Brett Kavanaugh’s Supreme Court confirmation. Just this week, Special Counsel Robert Mueller says someone offered a woman money to fabricate sexual harassment claims against him.“It doesn’t matter what your political affiliation is, there’s this sense in politics that winning is the most important thing,” Stumpf says.A new poll finds found 4 in 10 surveyed believe the movement has gone too far. The nation is split along party lines, with 75 percent of Republicans saying the #MeToo movement has gone too far, compared to 21 percent of Democrats.Sexual assault advocates say that can have an impact on victims coming forward or being believed.“From a survivor’s perspective, if you already felt the criminal justice might not be a space where you’re believed, your willingness to think that that’s going to get better in this political moment is probably not likely,” Stumpf explains. 1614

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