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SAN DIEGO (KGTV) - Looking for love in all the wrong places? San Diego is one of the top spots in the nation for singles, according to WalletHub.The website ranked cities based on data including share of single population, number of online dating opportunities, and nightlife options.The top cities included: 321

SAN DIEGO (KGTV) — It's a new season with new threads for the San Diego Padres.The Padres unveiled new home and away sets of uniforms sporting the team's classic brown colors during a fashion show-style event at Petco Park Saturday.Third baseman Manny Machado, first baseman Eric Hosmer, and shortstop Fernando Tatis Jr. were on hand to model the new look the Friars take into 2020. Two styles of the new uniforms featured a return to pinstripes, one on a white base reading "Padres" and the other on dark gray reading "San Diego." The third uniform was brown with gold "San Diego" across the chest and dark gray pants. 627

SAN DIEGO (KGTV) - Life is changing on Marine Corps Air Station Miramar, as dozens go into precautionary quarantine after exposure to COVID-19.The protocols you see around San Diego County are in effect on base, bringing the Health Protection Condition on base up to Level Bravo, according to Public Information Officer Capt. Matthew Gregory.The spectrum ranges from Alpha to Delta.RELATED: Third MCAS Miramar Marine tests positive for coronavirusThat means changes to daily life, starting at the gate."Our gate guards are now under a no touch ID policy, so the driver will keep hold of their ID. They'll get looked at by the MPs [Military Police] and wave them through," Capt. Gregory said.Restaurants on base are carry-out only. The chapel, tax center and gym are closed. Anyone on base who can work from home is mandated to.RELATED: Kearny Mesa hotel to be used as coronavirus quarantine site"The events around the coronavirus are unprecedented. I cannot remember in my lifetime anything that has happened on this scale," Capt. Gregory said.No tight formations, like you would see at Color Guard practice, or group meetings are allowed to comply with social distancing protocol.The base learned key practices from the CDC and Health and Human Services during the waves of Americans quarantined on base after returning from China, or a cruise. That helped them prepare for the cases they're now seeing on base.RELATED: San Diego-based Navy hospital ship to assist hospitals amid COVID-19 outbreak"We proactively set aside another barracks, cleaned it up, and that way we have a place for people who may be sick, who live on base, or require quarantine can go," Capt. Gregory said.As of Wednesday they have about 45 Marines in the building. Three tested positive for COVID-19. The others are there out of precaution after being exposed."Along with that comes plans for... having meals brought to them, laundry services, all those things, so units here on base are going to be responsible for their Marines who may be in quarantine or may be sick," he said.RELATED: San Diego and national closures, cancellations, postponements due to COVID-19Capt. Gregory said it's better to over prepare and look back thinking it was easy, than to under prepare and make things harder.He said the base is ready to take on any mission that comes their way as they continue to balance the community's needs, their Marine's needs, as well as their ability to protect. 2458

SAN DIEGO (KGTV) — It’s one of the few drugs shown to help fight the novel coronavirus, and a large federal study on remdesivir just entered a new phase.Previous research sponsored by the National Institute for Allergy and Infectious Disease showed remdesivir shortened recovery time in hospitalized COVID-19 patients on average from 15 days to 11 days.Now scientists and doctors are racing to find the perfect cocktail against COVD-19 by blending remdesivir with other drugs.California-based Gilead Sciences originally developed the drug to fight Ebola, but remdesivir was never approved. Gilead Sciences has offices in Oceanside.The drug works by interrupting the virus’ ability to replicate.“Remdesivir acts by shutting down virus production,” said Dr. Peter Chin-Hong, an infectious disease expert at University of California San Francisco. “It just forces the virus to stop making virus children.”Dr. Chin-Hong is studying remdesivir as part of the NIAID research.The problem is that stopping the virus from replicating isn’t enough for some severely ill patients. They suffer from a second problem: massive inflammation from the immune system’s war with the virus.That’s why scientists are trying a cocktail approach.“You have the virus to take care of, but you also have the body's response to the virus, which is inflammation, that you also have to take care of,” said Dr. Chin-Hong.Researchers started testing the first drug cocktail in May, using an arthritis drug called baricitinib that tames inflammation.But as the data on that part of the study gets crunched, researchers began testing the second cocktail this month, a combination of remdesivir and interferon beta.“Interferon beta is something we produce naturally to fight viruses,” said Dr. Chin-Hong. He said studies have shown people who don’t produce enough interferon beta struggle to fight off the virus.Researchers selected interferon beta after two small studies showed promising results against the coronavirus.Interferon beta can both reduce inflammation and kill viruses, so doctors are hoping it will be a potent one-two punch with remdesivir.Dr. Chin-Hong said he and other researchers started administering the new cocktail this month.Some patients will receive the cocktail, some will receive a placebo, and some will get remdesivir only. This kind of clinical trial is called an adaptive trial, which the FDA started encouraging in 2004. After each phase, the winning drug or cocktail will be tested against a new challenger.Dr. Chin-Hong said the eventual cocktail may include three or more drugs, similar to HIV medication. 2617

SAN DIEGO (KGTV) - It's one of San Diego's crown jewels. The Hotel Del Coronado has been a landmark of America's Finest City since 1888.While its walls are steeped in history, recently, rumors swirled that a face-changing paint job to the hotel's lobby was coming.Facebook users on the "Coronado Happenings" page voiced worries that the iconic hotel planned to paint its wood-finished lobby white.Do you have a fact or fiction question? Submit your question to 10News here.Those rumors, however, are just that, according to the hotel.Hotel Del Coronado's Public Relations Director Sara Baumann told 10News there were discussions of possible upgrades to retail shops on the hotel's lower level, but nothing regarding painting planned for the lobby. Nothing has been set in stone for any upgrades in any space, as well, Baumann added.Could that change even be made to a National Historic Landmark? According to the National Parks Service, "property owners are free to make whatever changes they wish if Federal funding, licensing, or permits are not involved." 1086