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U.S. government officials are putting an early end to a study testing an Eli Lilly antibody drug for people hospitalized with COVID-19 because it doesn’t seem to be helping them.Independent monitors had paused enrollment in the study two weeks ago because of a possible safety issue. But on Monday, the National Institute of Allergy and Infectious Diseases, which sponsors the study, said a closer look did not verify a safety problem but found a low chance that the drug would prove helpful for hospitalized patients.It is a setback for one of the most promising treatment approaches for COVID-19. President Donald Trump received a similar experimental, two-antibody drug from Regeneron Pharmaceuticals Inc. on an emergency basis when he was sickened with the coronavirus earlier this month.In a statement Lilly notes that the government is continuing a separate study testing the antibody drug in mild to moderately ill patients, to try to prevent hospitalization and severe illness. The company also is continuing its own studies testing the drug, which is being developed with the Canadian company AbCellera.Antibodies are proteins the body makes when an infection occurs; they attach to a virus and help it be eliminated. The experimental drugs are concentrated versions of one or two specific antibodies that worked best against the coronavirus in lab and animal tests.Lilly and Regeneron have asked the U.S. Food and Drug Administration to grant emergency use authorization for their drugs for COVID-19 while late-stage studies continue. Lilly says its request is based on other results suggesting the drug helps patients who are not hospitalized, and that it will continue to seek the FDA’s permission for emergency use.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 1928
UPDATE: 2:53 p.m. PUSD officials said secure campus mode was lifted.SAN DIEGO (KGTV) - A Del Sur school went into secure campus mode Friday due to a threat, the Poway Unified School District confirmed. The threat was made from one student to another at Design 39 (17050 Del Sur Ridge Rd), school district officials told 10News. They did not elaborate on the nature of the threat. Classes remained underway Friday afternoon about 2:30 p.m. but the classroom doors were locked. San Diego Police were called to the scene to investigate the situation. The Poway Unified School District issued a statement to parents which was not made immediately available. 661

Veterinarians have a warning for pet owners about an ingredient in some foods — including peanut butter — that can be toxic to your pet.It's a sweetener, called xylitol, that's found in different brands of peanut butter, and it can make your pet sick, or even kill them. The ingredient can also cause liver failure."It's kind of horrible to think about because it's common knowledge — everyone gives their dog peanut butter," Laura Lovely said.Lovely said it's devastating to learn her dog Sweetie's favorite snack could send her to the emergency room."Whenever she wants kind of a healthy treat, because it has a lot of protein, and when she takes her medication," Lovely said.It's a food Lovely said she and Sweetie both enjoy."Xylitol is a wonderful low calorie sweetener for you and me but it can be deadly for our dogs," veterinarian Dr. Christopher Byers said.It's not just in peanut butter. Byers said you'll find xylitol in a number of products."Certain brands of peanut butter, toothpaste, certain gums, certain breath mints," Byers said.He said your dog can be exposed to it by accident."One of the more common gums that we encounter in the emergency room is Orbit," Byers said. "Orbit is a great product, but it does contain xylitol."Within a half-hour, he said, your dog's blood sugar will start to plummet."They can be lethargic. They can collapse. They can even have seizures," Byers said.So it's essential for all dog owners to check labels, he said."I think it's awful," Lovely said. "if it's not healthy for dogs, how is it supposed to be healthy for us as well?" Byers said they see xylitol intoxication in dogs several times a week, and that if you see the signs, get your dog to the emergency room as soon as possible. 1791
United Airlines announced Wednesday plans to return 25,000 flights systemwide during the month of August in hopes that more people will resume traveling. Despite the massive number of flights being added to the schedule, United said that it will only run 40% of the number of flights it ran in 2019 in August.Domestically, United plans on adding 600 flights, meaning it will run 48% of its US flights in August. United projects that only 30% of US flights will fly in July compared to 2019."We're taking the same data-driven, realistic approach to growing our schedule as we did in drawing it down at the start of the pandemic," said Ankit Gupta, United's vice president of Domestic Network Planning. "Demand is coming back slowly and we're building in enough capacity to stay ahead of the number of people traveling. And we're adding in flights to places we know customers want to travel to, like outdoor recreation destinations where social distancing is easier but doing so in a way that's flexible and allows us to adjust should that demand change."On Tuesday, Delta announced the addition of 1,000 flights systemwide in July. Delta said it reduced the number of flights in the US by 65% in July. 1208
Tuesday marks a very special and important anniversary in the U.S. — 100 years since women got the right to vote.The Constitution's 19th Amendment was ratified on Aug. 18, 1920.The House of Representatives and Senate had approved the amendment the previous year, sending it to the states for ratification. Three-fourths of states had to ratify the amendment. The last one to do so, Tennessee, officially made the amendment part of the Constitution.The push for women's suffrage had been underway for years, starting in the mid-19th century. For decades, several generations of women's sufferage advocates marched, lobbied and practiced civil disobedience to get women the right to vote.Their long, brave fight for change culminated in the drafting, passage and ratification of the 19th Amendment. 804
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