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New results on a possible COVID-19 vaccine from Oxford University and drugmaker AstraZeneca suggest it is safe and about 70% effective.Some experts say that shows it is likely to win approval, but questions remain about how well it may help protect those over 55. That's a key concern for a vaccine that health officials hope to rely on around the world because of its low cost, availability and ease of use.Partial results from tests of the vaccine in the United Kingdom, Brazil and South Africa were published Tuesday by the medical journal Lancet.“Today, we have published the interim analysis of the Phase III trial and show that this new vaccine has a good safety record and efficacy against the coronavirus,” said Professor Andrew Pollard, Director of the Oxford Vaccine Group and Chief Investigator of the Oxford Vaccine Trial. “We are hugely grateful to our trial volunteers for working with us over the past eight months to bring us to this milestone.”Researchers claim the vaccine protected against disease in 62% of those given two full doses and in 90% of those initially given the half dose. However, independent experts have said the second group was too small — 2,741 people — to judge the possible value of that approach and more testing is needed.The interim analysis for efficacy was based on 11,636 participants accruing 131 symptomatic infections from the Phase III trials.In addition to the Oxford led program, AstraZeneca is conducting a large study in the US and globally. In total, Oxford University and AstraZeneca expect to enroll more than 60,000 participants globally.The company says it’s also making progress in manufacturing with a capacity of up to 3 billion doses of the vaccine in 2021 on a rolling basis, pending regulatory approval. The vaccine can be stored, transported and handled at normal refrigerated conditions for at least six months and administered within existing health care settings. 1940

NORFOLK, Va. (AP) — The U.S. government will try to stop a company's planned salvage mission to retrieve the Titanic's wireless telegraph machine. Federal attorneys are arguing the expedition would break federal law and a pact with Britain to leave the iconic shipwreck undisturbed.In their filing, the agreement with the U.K. says disturbing the Titanic where so many lives were lost should be respected. U.S. attorneys filed a legal challenge before a federal judge in Norfolk, Virginia, late Monday. The expedition is expected to occur by late August. The U.S. government filed its challenge before the same federal judge who ruled last month that the salvage firm could recover the radio. Its distress calls to other ships are credited with saving the lives of some 700 people after the Titanic struck an iceberg in 1912. 833

NEW YORK (AP) — Mary Trump's scathing memoir about her uncle, President Donald Trump, is nearly a million seller on preorders alone. Simon & Schuster announced Thursday that Mary Trump's "Too Much and Never Enough" had sold a company record 950,000 copies as of its date of sale, earlier this week. Another anti-Trump book from Simon & Schuster, former National Security Advisor John Bolton's "The Room Where It Happened," sold nearly 800,000 copies in its first week when released last month. President Trump and his allies had tried to stop both books from coming out but have failed. 602

NOBLESVILLE, Ind. — The family of a girl who was wounded in the shooting at Noblesville West Middle School on Friday morning is thanking well-wishers for their prayers.In a statement, the Whistler family said their daughter, Ella, is doing well at Riley Hospital for Children and she is stable.Ella's family went on to say, "We'd like to thank everyone across the country who prayed for our family today. We've felt those prayers and appreciate each of them. We'd also like to thank the first responders, Noblesville police, Indiana State Police and the medical staff and surgeons at Riley."The statement goes on to ask for privacy for her family as Ella recovers.Here is the entire statement: 721

NEW YORK, N.Y. - Walking around the city is a learning experience.Two life-long friends have written a book about their travels and discoveries on the streets of Manhattan.Lori Zimmer started writing and walking about a decade ago after losing her job.“I never had the time. Now I was taking note,” Zimmer said.“Art Hiding in New York” was born when she visited Maria Krasinski, who illustrated the book. It was an artistic choice to use drawing instead of photographs.“It’s a little more playful and fun. Illustrations brought it to life,” Krasinski said.Click here to read about and purchase the book. The chapters feature undiscovered places and tell the stories of some public art.This story was first published by Greg Mocker at WPIX in New York, New York. 769

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