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A hospital in Orange County, California was locked down Tuesday morning after police said someone at the facility called and claimed to have a gun.The incident was reported just after 8:15 a.m. local time at the Orange County Global Medical Center in Santa Ana, police said.Santa Ana police said they received a call from someone inside the hospital claiming to be in possession of a gun. The caller did not say anything further, police said.The hospital was locked down as a precaution while about 40 officers conducted a floor-to-floor search, including the facility’s basement and roof.  608

A genetic analysis of COVID-19 patients suggests that blood type might influence whether someone develops severe disease.Scientists who compared the genes of thousands of patients in Europe found that those who had Type A blood were more likely to have severe disease while those with Type O were less likely.Wednesday’s report in the New England Journal of Medicine does not prove a blood type connection, but it does confirm a previous report from China of such a link.“Most of us discounted it because it was a very crude study,” Dr. Parameswar Hari, a blood specialist at the Medical College of Wisconsin, said of the report from China. With the new work, “now I believe it,” he said. “It could be very important.”Other scientists urged caution.The evidence of a role for blood type is “tentative ... it isn’t enough of a signal to be sure,” said Dr. Eric Topol, head of the Scripps Research Translational Institute in San Diego.The study, involving scientists in Italy, Spain, Denmark, Germany and other countries, compared about 2,000 patients with severe COVID-19 to several thousand other people who were healthy or who had only mild or no symptoms. Researchers tied variations in six genes to the likelihood of severe disease, including some that could have a role in how vulnerable people are to the virus. They also tied blood groups to possible risk.Most genetic studies like this are much larger, so it would be important to see if other scientists can look at other groups of patients to see if they find the same links, Topol said.Many researchers have been hunting for clues as to why some people infected with the coronavirus get very ill and others, less so. Being older or male seems to increase risk, and scientists have been looking at genes as another possible “host factor” that influences disease severity.There are four main blood types — A, B, AB and O — and “it’s determined by proteins on the surface of your red blood cells,” said Dr. Mary Horowitz, scientific chief at the Center for International Blood and Marrow Transplant Research.People with Type O are better able to recognize certain proteins as foreign, and that may extend to proteins on virus surfaces, Hari explained.During the SARS outbreak, which was caused by a genetic cousin of the coronavirus causing the current pandemic, “it was noted that people with O blood type were less likely to get severe disease,” he said.Blood type also has been tied to susceptibility to some other infectious diseases, including cholera, recurrent urinary tract infections from E. coli, and a bug called H. pylori that can cause ulcers and stomach cancer, said Dr. David Valle, director of the Institute of Genetic Medicine at Johns Hopkins University.Bottom line: “It’s a provocative study. It’s in my view well worth publishing and getting out there,” but it needs verification in more patients, Valle said.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 3086

A long-running dispute between scouts has now ended up in a Manhattan court.The Girl Scouts of the USA has filed a trademark infringement lawsuit against the Boy Scouts of America after it announced that it would drop "boy" from the name of a program in 2019. The boys' group has already begun to welcome older girls.The Girl Scouts said in the complaint filed in Manhattan federal court Tuesday that the Boy Scouts do not have the right to use "scouts" or "scouting."It also alleged that the Girl Scouts brand and activities will be marginalized by the Boy Scouts rebranded program, Scouts BSA. 603

A federal judge in San Diego on Friday called the Trump administration's plan outlining how the US government intends to reunite migrant children who were separated from their families with parents who have been deported "very impressive."US officials will first work to determine parentage and resolve any safety concerns for the child and then seek to reunite families. The submitted plan said there are 365 separated children with parents outside the US in the care of the Department of Health and Human Services, but officials later corrected that number.Scott Stewart, deputy assistant attorney general, said during a 40-minute joint status call Friday afternoon among the judge, the government, the American Civil Liberties Union and other nongovernmental organizations assisting with reunifications of separated families that the government actually has 386 children in its custody whose parents were deported. Stewart clarified that the reunification plan filed late Thursday night "was not made up to date." 1024

A federal appeals court has ordered a judge to dismiss the government's case against former National Security Adviser Michael Flynn, marking an abrupt end to a years-long legal fight.The New York Times and CNN confirmed the ruling Wednesday morning.Flynn pleaded guilty to lying to the FBI in 2017 about his conversations with then-Russian Ambassador Sergey Kislyak as President Donald Trump prepared to take office after winning the 2016 election. He attempted to withdraw his guilty plea earlier this year, and in May, the Justice Department dropped all charges against him.Upon the Justice Department's decision, the judge in the case, Judge Emmet Sullivan, chose not to dismiss the case immediately. Instead, he sought counsel from the court of appeals. On Wednesday, a panel of three judges ruled that Sullivan did not have adequate reason to question the Justice Department's decision. 899