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Dr. Anthony Fauci delivered more good news regarding a potential coronavirus vaccine, indicating some Americans could begin getting vaccinated by the end of this month.During an interview with CNN’s Wolf Blitzer, Fauci, the director of the National Institute of Allergy and Infectious Diseases National Institute of Allergy and Infectious Diseases, said it’s possible a vaccine could begin reaching some Americans by the end of the month, but was confident some would begin getting vaccinated by the end of the year.Fauci’s declaration came on the same day Pfizer said that its Phase 3 vaccine candidate was showing an effectiveness of over 90%. Fauci said the announcement was promising, but a few more questions need to be addressed before it is given approval. Fauci said that things like the vaccine’s durability and effect on the elderly are among concerns that still need to be tackled.“We may have doses that we’re able to give to people by the end of November, beginning of December,” Fauci told CNN’s Blitzer. “Now you have to go through the hoops of making sure all of the I’s are dotted and the T’s are crossed about the safety and regulatory aspects of it, but we would be giving vaccine, very likely, by the end of this year. That is good news.”Last month, the FDA put into place guidelines on approving a vaccine, which was more restrictive than what the White House had hoped for. The FDA noted that a vaccine candidate must be at least 50% effective. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit.“In addition to outlining our expectations for vaccine sponsors, we also hope the agency's guidance on COVID-19 vaccines helps the public understand our science-based decision-making process that assures vaccine quality, safety and efficacy for any vaccine that is authorized or approved,” Peter Marks, M.D., Ph.D., director of the FDA's Center for Biologics Evaluation and Research, said.While it is possible some will begin getting vaccinated in the coming weeks or months, questions remain on how soon a majority of the country will have the opportunity to become vaccinated. The first Americans slated to become vaccinated will be health care workers and people with a high risk of coronavirus complications, such as the elderly and those living in assisted living facilities, according to an NPR report.Given that Pfizer’s vaccine candidate is showing a high level of effectiveness, Fauci called the development “extraordinary.”"We know there's light at the end of the tunnel, but that doesn't mean that we're going to give up the important public health measures that we continually still have to do every single day,” Fauci said.While there is urgency for both public health and economic reasons for a vaccine, some experts have expressed concern over the speed of a vaccine and whether the expedited timeline is long enough to demonstrate efficacy.Even though a vaccine could be ready by year’s end, trials will be expected to continue for over a year to monitor for possible side effects.According to the FDA, a typical Phase 3 trial would take one to three years.“NIH is committed to supporting several Phase 3 vaccine trials to increase the odds that one or more will be effective in preventing COVID-19 and put us on the road to recovery from this devastating pandemic,” said NIH Director Francis S. Collins, M.D., Ph.D. “We also know that preventing this disease could require multiple vaccines and we’re investing in those that we believe have the greatest potential for success.”Pfizer said based on current projections, it expects to produce globally up to 50 million vaccine doses in 2020 and up to 1.3 billion doses in 2021. 3823

EL CAJON, Calif. (KGTV) - Have you ever asked yourself what goes into a guitar? One of the biggest manufacturers in the world runs operations from El Cajon. As part of our 10News “Life in El Cajon” series, we take you inside the music powerhouse that is Taylor Guitars.Seven-hundred guitars a day are pumped out between the manufacturing plant in El Cajon and Tecate, Mexico. From its distribution center in Amsterdam, guitars go to all corners of the world. While guitars are sent to remote areas, they're also in the hands of music's most well known stars, from Taylor Swift, Prince, and George Straight, to Alan Jackson, David Matthews and Ben Harper, the list goes on.Chris Wellons, the VP of Manufacturing talks about the company's mission. First, at Taylor Guitars there's an emphasis on finding your fit. That means physical fit and musical fit. A guitar should be comfortable, and its sound should complement your playing style. Wellons says the company is a leader in sustainability. For every Koa tree they cut down in Hawaii, they plant three behind it.Success has followed Taylor Guitars. It's bringing in 5 million a year. How? Wellons says valuing their work force, and their customers, as well as one other ingredient to greatness: courage."Just have the courage to pick up a guitar and try it," said Wellons.The philosophy is inscribed on the entry wall inside their El Cajon plant.The wall reads:We believe at the heart of every greataccomplishment you will find a singlecommon ingredient: COURAGE.It's courage that allows us to explore,to push forward,to venture into the unknown.And while the decision to do so may seemobvious afterwards, it wasn't at the time.Because each time we make the boldchoice, or go down the narrow road,we put something at risk.Our Ego,Our Reputation,Our Livelihood.Without courage we would never dare,never change, never inspire.That's why whether you're a guitar player,or a guitar builder, the world needs more of it.Step forward...music is waiting. 2009

Dr Pepper fans are struggling to find the soda on store shelves.The company told fans it is working to get more products out."We're doing everything we can to get it back into your hands. That means working with our distribution partners to keep shelves stocked nationwide while ensuring the safety of our employees," Dr Pepper said in a statement on social media. We know it’s harder to find Dr Pepper these days. We’re working on it – hang tight! Note: This applies to all flavors of Dr Pepper – including our newest permanent addition to the family, Dr Pepper & Cream Soda. pic.twitter.com/Kf0UedMuiw— Dr Pepper (@drpepper) August 10, 2020 Back in July, aluminum cans were also facing a shortage problem even before the pandemic hit because of high demand.“Can manufacturers are fully focused on filling the extraordinary demand from all sectors of the industry’s customer base,” said President of the Can Manufacturers Institute Robert Budway in a statement.Other products that are currently facing shortages because of COVID-19 are Clorox wipes, coins, meat, and toilet paper.The soda company is encouraging fans to contact their local retailer directly for the most up-to-date availability.This story was originally reported by Sydney Isenberg at KXXV. 1270

During a hearing with the House Oversight Committee, Postmaster General Louis DeJoy admitted he was not aware of the different prices of sending mail through the postal service.Representative Katie Porter asked DeJoy if he knew the price of a first-class stamp. Dejoy confidently answered 55 cents.Rep. Porter followed up by asking DeJoy if he knew the price to send a postcard. DeJoy paused, stumped by the question. “I don’t,” he responded. It’s 35 cents.She then asked how much it cost to send “one of those square cards.”“I’ll submit that I know very little about a postage stamp,” DeJoy said.The Congresswoman then asked about how many people voted by mail in the 2016 election. DeJoy said he did not know, and did not want to guess.Rep. Porter told DeJoy she was “concerned about your understanding of this agency,” because “you started taking very decisive action when you became postmaster general.”DeJoy has been the postmaster general for about 70 days.Rep. Porter’s quiz came toward the end of a multiple-hour House hearing in which DeJoy answered questions about his qualifications to be postmaster general, the removal of blue mail boxes, a policy about truck schedules, and observations about slow mail delivery this summer.This is not the first time Rep. Porter has stumped a witness during a hearing with a math problem. She got a lot of attention earlier this year when she asked representatives of the coronavirus task force the price of a full battery of coronavirus testing. She then got out a white board and wrote out the costs.After doing so, Dr. Robert Redfield, the director of the CDC, agreed to cover the cost of testing. 1657

Don’t expect BLM and social justice messages on basketball courts or jerseys in the NBA next season, according to league Commissioner Adam Silver.The 2020 NBA season has gotten a lot of attention for both the league’s response to the coronavirus pandemic with a “bubble” and their public embrace of social justice issues and the Black Lives Matter movement this summer.During a NBA Countdown interview on ESPN ahead of a playoff game earlier this week, Silver was asked about the league championing social justice and civil rights, but as Silver noted in a press conference recently, that has not been universally popular.“How committed are you to being that going forward?” host Rachel Nichols asked.Silver quickly responded, “We’re completely committed to standing for social justice and racial equality. It’s part of the DNA of this league.”He then said changes could come in how that commitment is manifested. The commissioner acknowledged the league has to sit down with the players and discuss for next season.“I would say in terms of the messages you see on the court on our jerseys, this was an extraordinary moment in time, when we began the discussions with the players and what we all lived through this summer,” Silver said.In July, when the league restarted their 2020 season from a so-called bubble in Orlando, “Black Lives Matter” was painted on the court floor. Players, coaches and staff stayed in Orlando this summer and drastically limited contact with the outside world and other people, in order to stop the spread of the coronavirus.Also this season, players were allowed to put slogans or phrases on their jerseys to highlight causes they support.The league was also the first large sports group to protest playing games in the wake of the shooting of Jacob Blake in Kenosha, Wisconsin. Instead, many teams and other leagues spent time focused on social justice issues.Blake is a black man who is now recovering at a rehabilitation center after being shot several times in the back by a police officer.So, what can fans expect in the 2021 season?“My sense is there will be some sort of return to normalcy. That those messages will largely be left to be delivered off the floor. And I understand those people who are saying ‘I’m on your side, but I want to watch a basketball game,’” Silver said.As for when the next season will start, Silver says everyone with the league needs a rest, mentally and physically, and they don’t have an exact start date at this time. They said it could be as early as Christmastime, but will likely be in 2021. 2572