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TODAY, President @realDonaldTrump is taking ACTION to preserve America's democratic principles and ensure law-abiding American citizens are fairly represented in Congress.https://t.co/fcRgFqQU87— Karoline Leavitt (@KLeavitt45) July 21, 2020 248

Things at grocery stores seem relatively calm now, in comparison to how it was back in March. Remember the toilet paper fiasco?But as we hear talk about another wave of coronavirus infections, some are wondering if grocery supplies will take another hit.We went to experts who track grocery data. They say what we saw earlier this year was historic.“Those mid-March weeks were the largest we've seen in the history of grocery shopping. I don't expect to ever see big waves like that again,” said Anne-Marie Roerink, President of 210 Analytics.People first stocked up on just cleaning items and then they started stocking up on all types of items, including pantry foods and that precious commodity – toilet paper.Roerink says that while it is possible people will stockpile again later this year, toilet paper may not be on the list. Cleaning items may become hard to find again. The timing of all this really depends on the virus and how cases evolve.“Should it come down to where the virus is big enough of a wave or we might go back down to a shelter in place, or where people feel more safe at home than they do out and about, I can see where our grocery spending will go back up,” said Roerink.Earlier this year, holidays like Mother’s Day and Father’s Day actually contributed to the clearing of grocery shelves. They’re typically holidays where we go out to eat, but that wasn't really an option in most places. So, people had to improvise.“All of a sudden, retail had to absorb all those dollars to take care of mom and cook her a fun brunch or dinner, so we had an enormous peak again for Mother's Day and Father's Day,” said Roerink.That means holidays like Thanksgiving and Christmas could change how things work out at the grocery store as well.Generally, supply and demand has started to normalize, but grocery sales are still about 10% higher than what they normally are. Though, prices could still change depending on the demand. 1952

TOPEKA, Kan. (AP) — A FedEx executive says a higher-than-normal volume of Christmas-season package deliveries won’t interfere with the company’s effort to ship coronavirus vaccine doses.Jenny Robertson, a FedEx senior vice president, said two trucks on Sunday moved doses of a vaccine developed by Moderna and the National Institutes of Health from a factory in Olive Branch, Mississippi, to the company’s world hub in nearby Memphis, Tennessee, so that shipments could be loaded onto its airplanes bound for multiple states.She said the company is keeping its networks for shipping the vaccine and handling Christmas packages separate.“Nothing’s more important than the delivery of the vaccine to us, but we have put in place distinct networks that are keeping e-commerce moving through our ground network and vaccines moving through our express network,” she said. “We’re able to manage this volume right now.”Robertson said the company has seen holiday-level volumes for shipping packages since March because consumers switched how they buy products during the pandemic. 1081

There’s been talk of a “blue wave” heading into the midterm elections, with more Democrats energized and ready to vote. But just two weeks before the midterms, a new poll suggests the wave could be crashing.The lead in the election polls Democrats once had has fallen. In many of the battleground House or Representatives races, candidates from both parties are running almost even, according to a Washington Post poll.Another report finds Republicans are outpacing Democrats in early voting in key states, many of which are seeing record turnout.President Donald Trump outlined what he feels has sparked the turnaround.“This will be the election of the caravan, Kavanaugh, law and order, tax cuts and common sense,” Trump says.Even Democrats are downplaying the chances of a “blue wave.”“If the election were held today, the Democrats would handily win the House,” Nancy Pelosi, Minority Leader of the United States House of Representatives, says. “I can only speak in the present tense because you never know in a couple of weeks.”The president just announced he'll hold at least another ten rallies before the midterms, meaning he will have spoken at more than 30 rallies in the final five weeks of the campaign.President Barack Obama is also on the road, campaigning for Democrats.“The consequences of anybody here not turning out and doing everything you can to get your friends neighbor's family to turn out, the consequences of you staying home would be profoundly dangerous to this country and to our democracy,” Obama said during a recent rally.In these final couple weeks, both parties are having rallies across the country to motivate their base and to see which party can convince more of their voters to turnout. 1733

Too few new antibiotics are under development to combat the threat of multidrug-resistant infections, according to a new World Health Organization report published Tuesday. Adding to the concern: It is likely that the speed of increasing resistance will outpace the slow drug development process.As of May, a total of 51 antibiotics and 11 biologicals -- medical products often made from natural sources -- are being developed, the new report said."The idea is that biologicals could replace use of antibiotics, which could help in overcoming the resistance problem," Peter Beyer, an author of the report and senior adviser to the WHO's Department of Essential Medicines and Health Products, wrote in an email.Seemingly, this large number of potential new drugs should suffice, yet it is not nearly enough.First, just 33 of the antibiotics in the pipeline target priority pathogens. This year, the WHO published a list of a dozen "priority pathogens": 12 separate families of antibiotic-resistant bacteria that pose the greatest threat to human health.Among the priority pathogens is a drug-resistant tuberculosis, which kills about 250,000 people around the world each year, and a variety of multidrug resistant strains -- Acinetobacter, Pseudomonas and various Enterobacteriaceae -- which are responsible for infections in hospitals and nursing homes and among patients whose care requires ventilators and catheters.Of the 33 potential medicines for treating priority bug infections, only eight are innovative treatments. The other 25 are simple modifications of existing families of antibiotics. At best, then, the 25 will serve as short-term solutions since it is expected bacteria will quickly adapt to and resist these new (though somewhat familiar) drugs, according to the WHO."It is difficult to speculate why companies develop specific new medicines," Beyer noted. "But in general many new treatments do not necessarily constitute advances over existing treatments."TB infections require a combination of at least three antibiotics, according to the new report, yet only seven of the new TB medicines are even in clinical trials. Soon, there will be a serious lack of treatment options for this infection, the report warns.The same is true for gram-negative pathogens, which can cause severe, often deadly infections typically in hospitals and nursing homes.Gram-negative bacteria have more complex cell walls than gram-positive, explained Beyer. "In a nutshell, it is more complex to develop a novel antibiotic that can penetrate the complex gram-negative cell wall and stay inside the bacterium," he wrote.Finally, the WHO sees too few oral antibiotics being developed. These are necessary "to target the critical priority pathogens (and) be accessible in low- and middle-income countries," Beyer noted.To address the problem of developing new antibiotics, the WHO and the Drugs for Neglected Diseases Initiative set up the Global Antibiotic Research and Development Partnership. However, new drugs alone cannot combat the threat of antimicrobial resistance. The WHO is also working to improve infection prevention and control while developing guidance for the responsible use of antibiotics."Always seek medical advice before taking antibiotics and then always follow the advice of the health-care professional," Beyer noted.The new report is a "fantastic (and very useful!) summary" of the antibiotic situation, wrote Bill Hanage, an associate professor of epidemiology at Harvard T.H. Chan School of Public Health, in an email. Hanage, who has also published studies of antibiotic resistance, was not involved in the new report.Although the risk of getting a completely resistant infection is low in the United States, about 2 million people each year become infected with "resistant enough" bacteria that are harder to treat, Hanage said. And every year, more than 20,000 people die of these infections."More resistant infections don't just mean you or someone you care about is more likely to die from one, they also mean healthcare will get even more expensive," Hanage said. "Many of the procedures we take for granted in medicine, from cancer treatments to surgeries, depend on our ability to handle infections that happen in the course of treatment."The number of new drugs in development is simply not enough, he said."The great majority will not make it into the hands of doctors or your treatment," Hanage wrote. "As the report states, for drugs to be used in humans they have to pass 3 hurdles, the phase 1, 2 and 3 trials. Drugs entering that pipeline have just a 14% chance of getting all the way through to be used in humans." 4676