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The creator of the Labradoodle cross-breed has said he inadvertently unleashed a "Frankenstein('s) monster."Wally Conron, 90, who worked for Guide Dogs Victoria in Australia when he bred the first Labrador-Poodle cross in 1989, spoke of his regrets at having begun a trend for designer breeds on an ABC podcast."I opened a Pandora's box and released a Frankenstein('s) monster," he said.His "big regret" is that his invention paved the way for "unethical, ruthless people" to breed the dogs without thinking of the health of their offspring.According to Conron, the majority of Labradoodles are "either crazy or have a hereditary problem," with healthy examples of the breed "few and far between."He believes that people have now gone too far with cross-breeding, which can increase a dog's risk of congenital disease, particularly down the generations. On the podcast, he laid particular scorn on the new Rottweiler-Poodle hybrid, known as a Rottle or a Rottie-Poo.Conron's original purpose in crossing a Labrador with a standard Poodle (which has a non-shedding coat) had been to provide a guide dog for a blind woman in Hawaii whose husband was allergic to dogs.The resulting litter of three was small, but one of the puppies did not trigger the husband's allergies and was sent to Hawaii to be her guide dog.As no one wanted the two remaining puppies, Conron asked the PR department at his work to spread the message of this new breed. Labradoodles quickly became popular in Australia and further afield.Now, designer breeds have become widespread -- but so has criticism of the consequences. Labradoodles, for example, can develop health problems common to Labrador Retrievers and Poodles such as hip dysplasia and eye disease.Colin Tennant, a British expert on dog behaviour with 45 years of experience in the industry, told CNN: "In essence, you are blindly breeding and altering genetics of the line without foreknowledge."Although Tennant said he doesn't have a problem with cross-breeding in general, he noted that breeders should pay more attention to dog's health.One example, he said, was the Bichon Frise, whose eyes water. "It must be in agony all the time," he explained. "They breed the face flat so they look humanoid because we find that attractive, with no consideration for the permutations we are producing with regards the dog's welfare or health." 2383

The New Mexico State Police released video on Thursday of a wild wrong-way police chase from earlier in the month of a wrong-way driver that caused a semi to jackknife. 181

The Humane Society of the United States went undercover, investigating animal testing at one of the largest contract research organizations in the world. Officials found dozens of beagles and hounds that were force-fed fungicides to test a new pesticide product at a lab in Michigan.The undercover video is hard to watch. "In some cases, the animals are forced to ingest substances either by putting a gel capsule down their throats or with a tube,” Kathleen Conlee, vice president of Animal Research Issues at the Humane Society of the United States, can be heard saying in the undercover video. For some, it’s hard to fathom. However, Conlee says this kind of animal testing happens more often than we think. "There are about 60,000 dogs at about 350 facilities in the United States right now, and I think the public is very shocked to learn that it's at that scale,” Conlee says. And that's just dogs. Conlee explains when you factor in all animals, the number being used for testing is closer to 25 million per year. "That's warm-blooded animals that doesn't include fish, reptiles, amphibians," she explains. In this case out of Michigan, 36 beagles were being used to test pesticides for a company called Dow Chemical Company. It’s a practice that is not against the law. "The company is doing legal activities,” Conlee says. “Nothing illegal was happening." Often times, Conlee says federal agencies like the FDA and EPA request animal tests to approve products or provide funding for experiments. Most recently, the U.S.D.A. was under fire by a separate animal watchdog group for alleged "kitten cannibalism,” where they report experiments involving feeding kittens to dogs. These are practices Conlee says should stop."We're going to be calling on these agencies to change their practices,” she says. 1826

The ill-fated Ethiopian Airlines flight that crashed shortly after takeoff on Sunday was packed with humanitarian workers and international experts, many of whom were bound for a major United Nations environmental summit in the Kenyan capital, Nairobi.Twenty-two UN staff members were among the 157 people killed after Flight ET302 plummeted into a field outside Addis Ababa, Ethiopia, UN Secretary-General spokesman Stephane Dujarric confirmed to CNN.The airline said passengers from at least 35 countries were on the flight, often referred to as a "UN shuttle" for ferrying staff between Addis Ababa, home of the African Union headquarters, and Nairobi, the UN's headquarters in Africa.But the plane was particularly full due to the 747

The father of a Sarah Lawrence College student was indicted on charges Tuesday for allegedly manipulating, abusing and extorting his daughter’s friends and other victims in a scheme netting him about million over nearly a decade, Manhattan U.S. Attorney Geoffrey Berman said.Lawrence Ray, 60, coerced false confessions from at least seven victims who admitted damages to him, his family, or friends and then extorted restitution in large sums of money, unpaid labor or prostitution, 498