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WASHINGTON, April 25 (Xinhua) -- Study by scientists at the Rockefeller University shows that anti-inflammatory drugs reduce the effectiveness of the most widely used class of antidepressant medications, the selective serotonin reuptake inhibitors (SSRIs), taken for depression and obsessive-compulsive disorder and anxiety disorders.This discovery, published online Monday in the Proceedings of the National Academy of Sciences, may explain why so many depressed patients taking SSRIs do not respond to antidepressant treatment and suggests that this lack of effectiveness may be preventable.The study may be especially significant in the case of Alzheimer's disease. Such patients commonly suffer from depression and unless this can be treated successfully, the course of the illness is likely to be more severe. Depression in the elderly is also a risk factor for developing Alzheimer's Disease and researchers have suggested that treating depression in the elderly might reduce the risk of developing the disease.In the recent study, investigators treated mice with antidepressants in the presence or absence of anti-inflammatory drugs. They then examined how the mice behaved in tasks that are sensitive to antidepressant treatment. They found that the mice's behavioral responses to antidepressants were inhibited by anti- inflammatory/analgesic treatments.They then confirmed these effects in a human population. Depressed individuals who reported anti-inflammatory drug use were much less likely to have their symptoms relieved by an antidepressant than depressed patients who reported no anti- inflammatory drug use. The effect was rather dramatic since, in the absence of any anti-inflammatory or analgesic use, 54 percent of patients responded to the antidepressant, whereas success rates dropped to approximately 40 percent for those who reported using anti-inflammatory agents."Many elderly individuals suffering from depression also have arthritic or related diseases and as a consequence are taking both antidepressant and anti-inflammatory medications. Our results suggest that physicians should carefully balance the advantages and disadvantages of continuing anti-inflammatory therapy in patients being treated with antidepressant medications," leader author Paul Greengard said.

UNITED NATIONS, Jan. 26 (Xinhua) -- China on Wednesday welcomed the smooth development of the south Sudan referendum, voicing its hope that the parties in south and north Sudan could reach a consensus at an early date on the outstanding issues through dialogue and consultations.Li Baodong, the Chinese permanent representative to the United Nations, made the statement in an interview with Xinhua after he spoke at the UN Security Council about the Chinese stance on the situation of Sudan.Earlier on Wednesday, the Security Council met to hear briefings from Atul Khare, UN assistant secretary-general for peacekeeping operations, and Ibrahim Gambari, the joint special representative of the African Union-United Nations Mission in Darfur (UNAMID), on the current situation in Sudan."China welcomes the smooth development of the south Sudan referendum, this is the result of the joint efforts of north and south Sudan and the international community," Li said."At present, priority should be given to the following work: First, continuous efforts should be made to fully maintain peace and stability in Sudan to enable the country to realize its long- term peace, stability and development," he said. "Second, efforts should be made to encourage the parties in south and north Sudan to continue their efforts for the full implementation of the Comprehensive Peace Agreement (CPA), particularly for a consensus at an early date on the outstanding issues."The referendum, with its week-long polling period ending on Jan. 15, will determine whether south Sudan remains a part of Sudan or becomes independent, in accordance with the 2005 CPA that ended a long-running north-south civil war.The referendum's preliminary results are expected to be announced by Feb. 2, and depending on whether appeals are launched in the courts, the final result will be declared on Feb. 7 or 14.

MOSCOW, Jan. 25 (Xinhua) -- China condemned the terrorist attack at Moscow's Domodedovo Airport that killed 35 on Monday, visiting Chinese State Councilor Dai Bingguo said on Tuesday."We have learned that a terrorist attack occurred at the Domodedovo Airport yesterday. We are simply shocked by this news. We condemn this terrorist attack," Dai said when meeting with Russian Foreign Minister Sergei Lavrov.During their meeting, Dai and Lavrov exchanged opinions on bilateral ties, regional situation and issues concerning the Shanghai Cooperation Organization and others.Dai met with Russian President Dmitry Medvedev and participated in the fifth round strategic security talks with Russian Security Council Secretary Nikolai Patrushev on Monday.

BEIJING, March 17 (Xinhuanet) -- A new study has shown that gene therapy can reduce symptoms in patients with Parkinson's, media reports said Thursday.The study, published in the journal Lancet Neurology, is the first to show positive results in a test of gene therapy against a sham operation in 45 U.S. Parkinson's patients.The treated group showed a 23.1 percent improvement on a scale of Parkinson's symptoms six months after treatment, compared to a 12.7 percent improvement for patients who received sham surgery, according to the published research."Gene therapy is no longer just a theory," said Michael Kaplitt, a neurosurgeon at New York-Presbyterian Hospital and Weill Cornell Medical Center, and one of the study authors. "We are getting much closer to a reality where this treatment can be offered to patients."In patients with Parkinson's disease, their brains get overactive after losing the normal supply of a chemical called GABA. The new treatment, gene therapy, works by inserting billions of copies of a gene into patients' brains that helps them produce more GABA.Kaplitt said the results might spur similar treatments for other brain disorders like Alzheimer's, epilepsy and depression.

TOKYO, Feb. 6 (Xinhua) -- Japanese Prime Minister Naoto Kan said Sunday that Japan is ready to reconstruct relations with China in cultural, economic, political and other areas, the Jiji Press reported."This year marks the 100th anniversary of China's Revolution of 1911, and next year will be the 40th anniversary of the normalization of Sino-Japanese relations," said Kan at the first session of the "China-issue" advisory committee, organized by the Japanese government and attended by personages from economic, cultural and academic circles."On this special occasion," Kan said, "Japan is ready to rebuild relations with China in various areas such as culture, economic and politics."According to local media reports, participants at the meeting put forward suggestions such as "China is a promising market in the economic area, and ties with China are thus of great importance" and "people-to-people exchanges need to be promoted in areas of culture, sports and arts."The committee is scheduled to submit the final advisory report to the government in mid-April.

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