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When I was diagnosed, I kept wanting to talk to someone who had been through this before and had done well, Green said. "But it seemed like nobody had heard of this or had any connection with anyone who had this, and that's when I realized how incredibly rare it was."Ocular melanoma refers to a malignant tumor that develops from cells called melanocytes that produce the dark-colored pigment melanin, which is present in people's skin, eyes and hair and the lining of some internal organs, according to the Ocular Melanoma Foundation.Symptoms vary by person but generally include blurry vision, spots in the visual field and vision loss, according to Dr. Marlana Orloff, an oncologist at Jefferson University Hospitals in Philadelphia, who is treating a number of the people in the Alabama group."For the primary eye tumors, it will either be incidentally picked up on routine eye exam having no symptoms, or more commonly patients have symptoms of a retinal detachment with flashes and floaters or blurry vision," Orloff said.Ocular melanomas are the second most common type of melanoma -- after cutaneous, or skin, melanomas -- and represent about 5% of all melanoma cases. However, ocular melanomas behave much differently than cutaneous melanomas and are generally considered to be more lethal, according to Orloff."Even though people want to lump it in with skin melanoma, we know that it's a very different disease, and a lot of the treatments for skin melanoma don't work for eye melanoma. There's really nothing officially FDA-approved to treat eye melanoma," Orloff said.In about 50% of ocular melanoma cases, the cancer spreads, or metastasizes, to the liver. Only about 80% of patients with liver metastases survive longer than a year, according to a 2005 study.But Allyson Allred, a preschool teacher in Birmingham, has beaten those odds."My doctor said only 3% make it as long as I have. Ninety-six percent of the people die once it spreads to their liver, and mine spread to my liver in 2008," Allred said.Allred was diagnosed with ocular melanoma in 2001, at the age of 31, 11 years after she graduated from Auburn. She was the second person in her group of friends to be diagnosed with the condition, she says."I was the second one diagnosed from Auburn, and I'm the one who told my doctor in Philadelphia that I had two friends with the same cancer, and that's when they realized there may be a cluster in Auburn and started researching this," Allred said.Allred has undergone two liver resections and is receiving radiation to shrink metastatic tumors that have spread to at least nine places in her body, she said."The cancer in my liver is stable, but in December, it went to my adrenal glands, a place near my kidney, a place near my diaphragm and a place next to my thyroid. So I did radiation on all those four spots. And last week, I found out that it had gone to my brain, and began radiation on my brain," Allred said.There is no known cure for ocular melanoma, although radiation therapy and surgery can help prolong the length and quality of life, according to Orloff."Once they're diagnosed, the treatment is often radiation," Orloff said, "or if the tumors are very large or depending on location, enucleation, or removal of the eye," may be necessary.The exact cause of ocular melanoma is still unknown. Individuals at highest risk include those with light eye color, those with light skin color and those exposed to high levels of artificial UV radiation. People with certain occupations, such as cooks and metal workers, also appear to have an increased risk, according to a 2001 study.No common cause has been identified in the current group of cases, Orloff says."We are not calling them official clusters. In order to meet the definition of a 'cluster,' you need to look at the expected incidence and observed incidence, and for a number of reasons it's been hard to qualify these as true clusters," Orloff said."But certainly, it's a unique accumulation of cases," she added.The Alabama Department of Public Health indicates it is evaluating the recent increase in cases but says it has not identified a common source."We are working closely with Auburn, a survivor we have connected with and Dr. Orloff's team," said Justin George, director of cancer epidemiology at the Alabama Department of Public Health. "We are collaborating and working in an advisory role; the survivor who has spoken out is providing us a complete list of all those who have been sickened, and then we will work to verify the incidents and make sure the cases meet the definition of ocular melanoma."Auburn said in a statement that it is "working closely with the Alabama Department of Public Health, which is leading the review of area cases of uveal melanoma. Researchers from the Sidney Kimmel Cancer Center and the coordinator of research in North Carolina have also been involved."While we have been informed by ADPH officials that it would be premature to determine that a cancer cluster exists in the area, we are cooperating fully with their work. The health and safety of our students, employees and alumni are of the utmost importance."Allred believes the group of cases among former Auburn students is no coincidence. She and at least two other patients lived in neighboring sororities and were all education majors, she said.Green and another patient "were in the same sorority, and my sorority dorm was right next to theirs. And we were all education majors," Allred said."We need the funding for the research to figure out what possibly could be the environmental cause. ... There must be some link, and if we can find that link, we're that much closer to finding a cure and preventing people from continuing to get this," she added.Three of the physicians treating the Alabama cases have also organized a task force to help raise awareness and funding for research into the causes and treatments of ocular melanoma, according to Allred."Auburn has so far not contributed money, so we're going to go back and try to get some other options to get our funding," she said."But we've had lots of people praying for us, and I believe in the power of prayer," Allred added. "I have a strong faith that the Lord is my healer, and we have many hundreds of thousands of people praying who have gotten us through this." 6337

We are taking significant action to prepare for a future where adult smokers overwhelmingly choose non-combustible products over cigarettes, Altria said in a statement. "We have long said that providing adult smokers with superior, satisfying products with the potential to reduce harm is the best way to achieve tobacco harm reduction." 337

Wednesday, March 27, is American Red Cross Giving Day. The organization describes Giving Day as "an opportunity for local communities to come together on one day to help the families who have been impacted by a home fire or other disaster and who urgently need Red Cross services to get back on their feet. "If you would like to donate, visit www.redcross.org/donations/ways-to-donate/giving-day.html. 401

Two months ago, a prosecutor brought a case against me.She claimed she had evidence of a crime—but she’s produced none.She said her investigator would find the truth. Instead, her investigator lied under oath and created false evidence.  And she is using thousands and thousands of taxpayer dollars to do all of this.Her case is falling apart—so today, she’s brought a new one.By now, everyone knows what this is: this prosecutor will use any charge she can to smear me.Thank goodness for the Constitution and our court system. In the United States of America, you’re innocent until proven guilty. In the United States of America, you get your day in court.And when I have my day in court, I will clear my name. People will know the truth.The latest charge is about my work at the Mission Continues. When I came home from Iraq after service as a Navy SEAL, I started the Mission Continues to help veterans. In the seven years I ran that organization, we helped thousands of veterans, won national awards for excellence, and became one of the finest veteran’s charities in the country. Those were some of the best years of my life, and I am grateful every day for the chance to help the men and women I served with.I stand by that work. I will have my day in court. I will clear my name. This prosecutor can come after me with everything she's got, but as all faithful people know: in time comes the truth. And the time for truth is coming. 1444

Watts will go next to a regional diagnostic center in Denver for an evaluation and it will then be up to the Colorado Department of Corrections to decide if Watts will be house in Colorado or moved out of state, Rourke said. Rourke said the DOC was “an exceedingly professional organization that will see to his safety and will place him in a prison where they feel is most appropriate for him.”Rourke also said that the Rzucek family has kept investigators and prosecutors going throughout the case and called it “an honor” to work with them.He said that he would be seeking restitution for the Rzuceks from what assets Chris Watts does have and said there would likely be ongoing costs to pay for counseling and therapy costs for Shanann’s family, in addition to the burials and funerals.The family also filed a civil lawsuit Monday to try and keep Chris Watts from benefiting from the story or the case in the future, the family’s attorney and the court confirmed Friday afternoon.Rourke acknowledged there would still be a long road ahead for the family, but he said their work with him and police has been second-to-none.“The thing that I will tell you gets us up and gets us moving every day is that family over there,” Rourke said of the Rzuceks. “They were great to work with under awful circumstances. … It’s been tough. Thank you to Frank, Sandy and Frankie for all you have participated in, all you’ve been subjected to. It’s been an honor.” 1452