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Scientists are working to eliminate a type of heart disease in dogs using gene therapy. They're zoning in on a heart condition called mitral valve disease that’s common in 6% of dogs. Scientists are using Cavalier King Charles spaniels for the research. They tend to develop it at a younger age. Scientists at Tufts University have already tested gene therapy in mice. A virus is injected into them to deliver DNA to cells which causes them to create a protein. What it essentially does is stops the heart valve from getting thicker, stopping the valve from leaking. Researchers are now moving on to testing this in dogs. But they think the treatment could go beyond just canines. “Many of the dog diseases are naturally occurring and really great models for human disease,” says Dr. Vicky Yang, a veterinary cardiologist and research assistant professor at Cummings School of Veterinary Medicine at Tufts University. “And I can see this, if it becomes successful in dogs, potentially going into thinking about treatment for humans for mitral valve disease.”The biotech company behind the treatment agrees. It says it could also expand beyond heart problems. “I think a larger question, though, is if we are able to prove this thesis of treating aging, making the animal generally healthier, could also treat heart failure, what other diseases could we treat in dogs?” says Daniel Oliver, the CEO of Rejuvenate Bio. “And could we progress this treatment onto past dogs and other animals and possibly humans?” The gene therapy would only be used for dogs just starting to experience heart problems.Researchers still need to make sure the gene therapy is safe for all breeds before they make it available to the public. 1730
A bill that would ban nearly all flavored tobacco products was passed by the House of Representatives on Friday.The "Reversing the Youth Tobacco Epidemic Act of 2019," or 183
A federal judge has ordered Chelsea Manning released from jail after being incarcerated since May for refusing to testify to a grand jury. U.S. District Judge Anthony Trenga ordered the release of the former Army intelligence analyst Thursday after prosecutors reported that the grand jury that subpoenaed her has disbanded. The judge left in place more than 0,000 in fines he imposed for her refusal to testify to the grand jury, which is investigating WikiLeaks. A hearing had been scheduled for Friday; Manning had argued that she had shown she proved she could not be coerced into testifying and therefore should be released. On Wednesday her lawyers said she attempted suicide while at the Alexandria jail. 726
2018 was the deadliest year for hot car deaths in the United States, according to a study released on Wednesday by the National Safety Council. According to the National Safety Council, 51 children died in 2018 from pediatric vehicular heatstroke. Last year's figure tops the previous record of 49 related fatalities set in 2010. The Council said that an average of 38 children die a year in the United States from being left in a hot car. Since 1998, 47 states have had at least one pediatric vehicular heatstroke fatality. The study also found that related deaths have occurred in the United States during every month of the year. The National Safety Council has an online 687
A couple who had been together for nearly 65 years have died on the same day at a St. Louis-area nursing home.Jack and Harriet Morrison’s beds were placed next to each other in their final hours, allowing them to hold hands, the 241