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It's a feeling of extreme work stress that's long been embedded in the cultural lexicon, and now it might be codified in your medical records as well.Burnout is now a legitimate medical diagnosis, according to the 226

KANSAS CITY — Maureen Boesen has always known cancer risk was high in her family."We're able to really track our history of breast cancer back to the late 1800s and early 1900s," Boesen said. "My grandmother actually passed away from ovarian cancer when she was 44. She had five sisters and none of them lived to the age of 50. Then, my mother was diagnosed with breast cancer when she was 32. We knew there was something going on and that it was a very young age."When Boesen and her two sisters were ages 3, 5 and 7, their mom was already receiving chemotherapy for stage 2 breast cancer. Because of the extensive family history, the girls were part of a study at a university in another part of the Midwest. Their mom was hoping to help the world better understand what was killing so many women. She was hoping to better her daughters' chances for survival."We were all tested in the same exact room," said Boesen's sister, Bridget Stillwell. "I can even remember what the room looked like." Because the girls were so young, and the health threat still likely years away, they wouldn't receive their DNA test results until they turned 18."We knew we were part of a study," Boesen said. "We knew our results were waiting for us, but we didn't know what they were."When asked if she found that wait frustrating, she said emphatically it was not."Quite the opposite. We felt empowered," she said.She didn't get the results right away. The sisters knew there was nothing they could likely do at age 18 even if their test results showed they'd inherited the BRCA gene mutation. The sisters all waited until they were around age 21. One sister was positive. One sister was negative. Boesen remembers meeting with the researcher to learn her results."We sat down and we had a conversation about what BRCA was and what it meant for my family," Boesen said. "It was a lengthy conversation, which made me very uncomfortable because why would a conversation that wasn't going to change my life last that long?"Eventually, the researcher told her she had inherited the gene mutation."It was just devastating because I knew what breast cancer and ovarian cancer can do to a family. You know, my first question out of my mouth was, 'Is there any chance this could be wrong?' The researcher said 'No.' "Boesen walked out of that meeting determined. She was going to make decisions to save her own life. She was going to have a bilateral prophylactic mastectomy. She would schedule a surgery to remove both breasts to prevent breast cancer."This was me doing what I was supposed to do and this was me being empowered and me being proactive and not waiting until I have a cancer diagnosis," Boesen said.She didn't want to feel like a ticking time bomb. She wanted to live.Boesen had the surgery to remove both breasts when she was just 23 years old. She went on to get married and have three children."I didn't get to breastfeed them. It was sad. I'm not brokenhearted or devastated about it, but it is sad to think I couldn't provide for my children like that," she said.At the time, she still believed she'd made the right decision because she was healthy.Once done having children, she knew there was another step that most people with the dangerous BRCA gene mutation have to consider."I knew that when I was done having children, I needed to have a complete hysterectomy," Boesen said.The BRCA gene mutation not only dramatically increases a woman's chance of developing breast cancer at a young age, it also significantly increases a woman's chance of ovarian cancer."The right thing to do and what the doctors say to do is have a complete hysterectomy by the age of 35 and I was in my early 30s," Boesen said.In 2018, she went to a hospital in Kansas City, Missouri, to start the process of preparing for her hysterectomy. Both her health care provider and her insurance company wanted a new DNA test. Everyone knew what the results would be, but they went through the motions to get the required confirmation she was positive for the deadly gene mutation which was so rampant in her family.The test results were supposed to be back in a few weeks, but it had been four and Boesen was starting to worry. Then, she got the call from the doctor."I was at work. And the first thing she said was, 'We need to talk', and my heart just sank," Boesen said. "She said, 'You're negative,' and I just started bawling."She was overwhelmed, confused and full of emotions."I was angry. I was regretful. I was happy. I was sad. I so desperately wanted to feel relief, 'Oh, thank God, this is the best day of my life,' but it wasn't," Boesen said. "It was just devastating."Boesen got another test to confirm the second test results. It also came back negative.She did not get the hysterectomy. There was no need now. There was no longer a threat that cancer was waiting to explode in her body. She now knew she had not inherited the BRCA gene mutation that had killed so many of her relatives.Dr. Jennifer Klemp of the University of Kansas Cancer Center has worked in the field of cancer genetics, specifically breast and female cancers, since 1997. She is the director of Cancer Survivorship and a cancer risk counselor. While she was not involved in Boesen's original research, she says she's not surprised."Twenty years ago, when we sent our first tests and BRCA 1 and 2 were the two genes we tested for, about 30-40 percent of the time we would get something called a 'variant of uncertain significance,' " Klemp said. "Basically, that meant we found a mutation or an error in the DNA, but we didn't know if that was associated with an increased risk of cancer. Today, using a reputable lab, that should be less than 1-2 percent."Klemp says things are changing rapidly in the field of genetic testing. If someone had a DNA test more than five years ago, they should consider having an updated test. She also says the at-home tests are good for finding out details about your ancestry, but they shouldn't be used to make major decisions about your health. For that, you'd want a health professional to order a commercial test through a certified, reputable lab. With more and more companies offering testing, and more medical professionals and patients interested in genetic testing for so many reasons, she says demand right now is outpacing supply."If you have 10 different labs doing testing, and you have every primary care, OB-GYN, oncology clinic, surgical clinic and any number of patients eligible for testing, it's a little bit of the wild west," Klemp said, adding there's no central repository for this patient and test information.As for Boesen, the university where the original research was done and the false positive originated offered to re-test her DNA. She is currently waiting on the results from what is now her fourth genetic test. She hopes it comes back negative, too, which is what the experts all expect. She believes, then, finally, she'll be able to move forward with her life. Boesen and her two sisters are writing a book about their experiences. Each of her sisters has a story to tell, too. Their book will be titled, " 7146

It appears that Wayne Newton's former home Casa de Shenandoah has been sold.According to Clark County records, his 36-acre ranch sold for .56 million on July 22, 2019.Newton's former ranch, which includes a white mansion and 6 other homes and stables, was sold to Smoketree LLC, which has a Las Vegas address. In addition, a nearby commercial property at 3310 E. Sunset Road that was home to a gift shop and theater was sold on Sept. 24, 2019. The commercial property was sold to Harsch Investment Properties, which brought several other parcels in the same area. The properties were sold by ICSD LLC, which is based in Texas.ICSD purchased the properties in 2010 and transformed it into a tourist attraction. However, it was eventually placed into Chapter 11 bankruptcy proceedings. Newton initially had a 20 percent stake in the company. It is now controlled by business executive Lacy Harber. Newton originally purchased the property in 1966. This article was originally written by Joyce Lupiani for KTNV. 1022

It was a tumultuous weekend in aviation as three planes crashed, killing all aboard, in separate incidents in Ethiopia, Colombia and the United States.On Sunday, an Ethiopian Airlines plane crashed shortly after takeoff, killing all 157 people on board. Investigators have started their search into what caused the deadly incident. On Saturday, a plane went down in Colombia, killing at least 12 people. On Friday, a small plane plunged into a Florida lake, leaving five dead.In the United States, there were two separate, non-fatal incidents Saturday, including severe turbulence that injured dozens of people as their plane approached New York's JFK airport, and an emergency landing in Newark, New Jersey.Sunday, March 10 An Ethiopian Airlines flight crashed minutes after taking off from Addis Ababa. Flight ET302, which was heading from the Bole International Airport in the Ethiopian capital to Nairobi, Kenya, lost contact at 8:44 a.m. local time -- six minutes after taking off.The plane was a Boeing 737 MAX 8, which had been delivered to the airline in November."As it is a fresh incident, we have not been able to determine the cause. As I said, it is a brand new airplane with no technical remarks, flown by a senior pilot and there is no cause that we can attribute at this time," said Tewolde GebreMariam, Ethiopian Airlines CEO.He told reporters the pilot reported technical difficulties after takeoff and asked for clearance to return to Addis Ababa. He was given clearance to turn back, GebreMariam said, citing the air traffic controllers' record.It's the deadliest airplane crash since an Indonesian Lion Air jet crashed soon after takeoff from Jakarta in 2018 -- killing 189 people. That plane was also a Boeing 737 MAX 8.2nd disaster involving Boeing 737 MAX 8 in six monthsThere is no suggestion yet as to what caused the latest disaster, and no evidence that the two incidents are linked in causality.Saturday, March 9Colombia flight crashesA plane in Colombia crashed Saturday, killing at least 12 people, according to Colombia's Civil Defense.The flight took off from San Jose del Guaviare and was headed to Villavicencio, in Colombia, the Civil Defense said.The plane called in an emergency at 10:40 a.m. and was later found in La Bendición, near Villavicencio, officials said.The cause of the crash is unknown.Turbulence sends dozens to hospitalIn a non-fatal incident on Saturday, at least 30 people suffered minor injuries when a Turkish Airlines flight encountered severe turbulence before landing at New York's John F. Kennedy International Airport.The injured were taken to hospitals and their wounds consisted mostly of bumps, bruises and cuts, said Port Authority spokesman Steve Coleman.The Turkish Airlines Flight 001, which had departed from Istanbul, hit major turbulence about 45 minutes before landing at JFK, Coleman said. The plane, a Boeing 777, arrived at JFK at 5:35 p.m. ET.Emergency landingAn Air Transat flight made an emergency landing at Newark Liberty International Airport in New Jersey after reports of a possible fire in the cargo hold, according to the Federal Aviation Administration.Passengers on board the Boeing 737 had to evacuate onto the airport's runway using emergency slides, according to FAA spokeswoman Kathleen Bergen.Flight TS942 had been flying from Montreal to Fort Lauderdale, when the pilot around 8:20 a.m. Saturday requested an emergency landing, saying there was smoke in the aircraft.Two minor injuries were reported, but they were unrelated to the smoke, said Coleman, the Port Authority spokesman.Friday, March 8Five people died when a small airplane fell into a Florida lake Friday, according to the Palm Beach County Sheriff's Office. Their bodies were found in the aircraft fuselage, according to the sheriff's office.The twin-engine Piper aircraft went down in Lake Okeechobee at approximately 3:30 p.m., while on approach to Pahokee Airport, according to the Federal Aviation Administration. The plane fell about 400 yards from shore and had departed from Tampa International Airport, the FAA said.The investigation will be handled by the FAA and National Transportation Safety Board. 4181

In the heart of Silicon Valley, people are keeping a pulse on a new product, as techies transition to foodiesAt Vina Enoteca, a restaurant located a few blocks from Stanford University, staff serve up new plant-based proteins.“We had a spike on the pizza with Impossible Meat,” says owner Rocco Scordella.Scordella put products created by the company Impossible Foods on his menu a few years ago. Now, they account for 20 percent of his pizza sales.“I think it’s as close as it can get,” Scordella says. “That’s why I think when a lot of meat eaters taste it they’re like, ‘Oh, wow. This is close to real meat.'"That’s the idea behind Impossible Foods, one of the top plant-based protein companies in the country. The company gave us an all-access inside look at their lab, showing us the science of turning plants into meaty-tasting patties.“The Impossible Burger is made of actually just four really simple categories of ingredients,” Laura Kliman, Impossible Foods senior flavor scientist, says. “We have proteins, our nutrients which generate flavor; we have our binders and we have fat.” They also use the blood red liquid hemoglobin.“Heme is what makes meat taste like meat,” Kliman explains. “It’s an iron containing molecule that is found in every living plant and animal and is essential for life.”This food tech startup was founded by a Stanford University biochemistry professor and a team of scientists back in 2011. After studying meat at the molecular level, they launched Impossible Burger 2.0 in 2014 and the sales have skyrocketed“Since then, we have grown from about 5,000 restaurants in January 2019 to now more than 9,000 restaurants that are serving the Impossible Burger,” Rachel Konrad, Impossible Foods chief communications officer.Those restaurants include some of the biggest fast food franchises in the world.“Just in the past six weeks, you’ve seen Burger King and Little Caesars jump on this trend,” Konrad says. “They’re both rolling out the Impossible Burger and the Impossible Sausage."Impossible Foods hopes to increase that demand by launching in grocery stores later this year.With a starting price point on par with grassfed beef and going down from there.“If we want to make a product that is affordable for many, we need to be using ingredients that are really part of the food chain now,” says David Lipman, Impossible Foods chief science officer.Lipman claims his team’s plant-based foods are better for your health and the environment.“Animal-based agriculture has been possibly the most damaging thing we are doing to the planet,” he says. “We can get the ingredients we need just from the earth at a 20th the amount of space and land, much lower water usage. So, we want to cut out that middle man and make the use of animals and agriculture no longer needed.”Cattle rancher Joe Morris, however, disagrees with those claims. “First of all, they haven’t been around really to understand if that’s true or not,” he says. “Whereas actually beef has been around since people have been people.”Morris’ family’s business T.O. Cattle Company is one of California’s oldest beef companies, dating back to the Gold Rush era. He believes in tradition over technology.“The people that are doing plant-based proteins are doing it with good intentions,” he says. “But there’s a failure to understand the ecology of just ecology and they really don’t know much about agriculture.”Instead, Morris says whatever damage caused by animal agriculture has to be healed by holistic animal agriculture.“The animals are incredible creatures and they do amazing work," he says. "And the results of their work is biodiversity beauty water in the ground. The plant-based proteins, there’s no romance, there’s no beauty there.”When it comes to customers, however, beauty is in the eye of the beholder. “It’s good,” says a man who bought an Impossible Burger from Burger King. “I could hardly tell it wasn’t a regular beef patty.”This customer also tells us that he added bacon to his plant-based protein patty. 4039

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