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SAN FRANCISCO (AP) -- Tommy Pham hit a go-ahead single in the 10th inning after Trent Grisham began at second base under baseball's new extra-innings rule, and the San Diego Padres beat the San Francisco Giants 12-7.Pinch-hitter Greg Garcia added a key two-run single against Tyler Rogers in the big six-run 10th.The Padres' bullpen couldn't hold a late lead for the second straight game but San Diego was still able to hold on this time.The Padres have won seven of their last 11 series in San Francisco and two in a row dating to late last season. 557

Sen. Amy Klobuchar, D-Minn., said in an MSNBC interview late Thursday that she is no longer interested in being Joe Biden’s running mate in this fall’s presidential election.Klobuchar was considered among the favorites to be pegged as Biden’s running mate. On Thursday, she took her name out of the running.Klobuchar cited her desire to see a woman of color as part of the reason she is taking herself out of the running. Biden, who previously said he would likely choose a woman as his running mate, has received pressure to choose a minority to be his running mate in the weeks since the death of George Floyd.With Klobuchar’s past as a prosecutor, and given Floyd was killed by officers in Klobuchar’s home state, many pundits believed her viability as a running mate dropped.“After what I have seen in my state, what I have seen across the country, this is a historic moment,” Klobuchar said. “America must seize on this moment and I truly believe, as I told the vice president last night, I think this is a moment to put a woman of color on that ticket."According to an Associated Press report last week, Sen. Kamala Harris and former National Security Advisor Susan Rice were among those being vetted.Klobuchar joined Biden in a crowded Democratic field vying for the party’s presidential nomination. Klobuchar briefly gained momentum following a solid performance in New Hampshire, but following lackluster results in Nevada and South Carolina, Klobuchar exited the race and endorsed Biden the night before Super Tuesday. 1536

Scientists at the University of Nevada, Reno School of Medicine (UNR Med), led by its Nevada State Public Health Laboratory (NSPHL) are studying a likely case of COVID-19 reinfection.Forty-eight days after testing positive for SARS-CoV-2 in April 2020 and after testing negative consecutively twice, a Washoe County, Nevada patient tested positive again, in June.The patient had tested negative on two separate occasions in the interim. The genomes of the patient’s virus samples were sequenced in April and June, displaying significant genetic discordance between the two cases, implying the patient was infected twice.“We examined the genomic material of the viruses and samples to investigate this, says NSPHL Director Mark Pandori. “It is just one finding, but it shows that a person can possibly become infected with SARS-CoV-2 a second time.”To solidify confidence in the case, Pandori and the research team partnered with the Washoe County Sheriff’s Office Biology Unit to conduct identity testing on the specimens and lab samples evaluated in the study to verify the specimens were from the same person.Embedded in the genomic material of SARS-CoV-2 is a detailed code that Pandori says may provide insight to a better understanding of this virus.“A virus has a biological genome like all living things. Since March, the NSPHL has analyzed the genomic RNA of approximately 200 positive COVID-19 samples from Nevadans who have tested positive for COVID-19,” said Pandori. “The power of genomic information could turn the tables in the fight against the coronavirus.” The information is shared to a world-wide database known as “GISAID”,” alongside the work of thousands of researchers.According to Pandori and the NSPHL-led research team, reinfection cases are a potential warning sign that it is possible to catch COVID-19 more than once, and with unpredictable severity.“If reinfection is possible on such a short timeline, there may be implications for the efficacy of vaccines developed to fight the disease. It may also have implications for herd immunity,” says Pandori. “It is important to note, that this is a singular finding. It does not provide any information to us with regard to the generalizability of this phenomenon.”Herd immunity depends on the theory that after natural infection, our immune systems will collectively protect us as a community from reinfection and further spread. There are currently many more unknowns than knowns about immune responses to COVID-19. “After one recover from COVID-19, we still do not know how much immunity is built up, how long it may last, or how well antibodies play a role in protection against reinfection,” says Pandori.”While research and scientific advancements continue to build, Pandori says the hard work of fighting this pandemic together will continue through the use of facial coverings, hand-washing, social distancing, as well as wide-scale testing, contact tracing, and isolation of new cases.“This is a novel disease. We still have a steep learning curve ahead and lots of work to do, especially as inconvenient truths arise,” says Pandori.The NSPHL team are publishing their COVID-19 reinfection findings. Their report is publicly accessible on the SSRN preprint server, at https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3681489. This story was first reported by KTNV in Las Vegas, Nevada. 3384

SAN YSIDRO (CNS) - A pedestrian was struck and killed by a van early Monday morning while he was attempting to cross a San Ysidro street, police said.It happened shortly before 1:10 a.m. in the 400 block of East San Ysidro Boulevard, San Diego police Officer John Buttle said.The unidentified man, believed to be in his 40s, stepped off the east curb of East San Ysidro Boulevard and was struck by a 64-year-old man driving a 1999 Chevrolet Astro van in the northbound lanes, Buttle said.The victim was pronounced dead at the scene, Buttle said.The driver remained at the scene and cooperated with officers, Buttle said.Alcohol or drugs were not believed to be factors in the collision, Buttle said. It was being investigated by traffic officers. 754

SAN FRANCISCO (AP) — University of California President Janet Napolitano, who oversaw historic expansions of the 10-campus system and championed immigrant students, but whose management structure faced criticism and embarrassing scrutiny, said Wednesday she will step down in August 2020.Napolitano, a former homeland security secretary and Democratic governor of Arizona, made the announcement at a meeting of the university system's Board of Regents in Los Angeles."My time at UC has been deeply gratifying and rewarding. I have been honored and inspired every day to serve this institution alongside incredibly dedicated, passionate people," Napolitano said in a statement. "The decision was tough — and this moment, bittersweet — but the time is right."Napolitano, 61, has battled a recurrence of breast cancer but said her health is good and did not play a role in her decision to step down."All of my tests are clear. So that was not a factor in my decision," Napolitano told reporters in a conference call, saying she will complete her seventh year in the job before stepping down."It seemed like a good time to have some fresh blood at the University of California," she said.During her tenure, Napolitano has overseen an expansion of the public university system, enrolling historic numbers of students and making it easier for in-state students to transfer from community colleges to the university system.She oversaw reforms of policies on sexual misconduct and was a staunch supporter of the rights of immigrant students.In 2017, the university joined a lawsuit challenging the Trump administration's decision to rescind the Deferred Action for Childhood Arrivals program, an action that led to injunctions that allowed hundreds of thousands of DACA recipients to extend their authorization to legally live and work in the U.S., including students in the UC system.But Napolitano also was criticized by state lawmakers after a state audit found problems with her office's financial management. A report from State Auditor Elaine Howle in 2016 found that Napolitano's office failed to disclose millions of dollars in reserve funds.It also said Napolitano's top aides had sought to suppress campus criticism of her office in surveys that were supposed to be confidential and sent directly to the state auditor.The investigators found that Napolitano had approved of the plan to review the survey responses. The audit said there was "insufficient evidence" to conclude that she knew of the full range of what her staff was up to or that she directly approved of any interference. But the investigation and subsequent oversight prompted a rare public rebuke by the UC's governing Board of Regents.Napolitano had a distinguished career before coming to California. As a partner in a prominent Phoenix law firm, she represented Anita Hill during the Senate Judiciary Committee's confirmation hearings for Supreme Court Justice Clarence Thomas in 1991. Hill accused Thomas of sexual harassment, which he denied.She was a popular Democratic leader in Republican-controlled Arizona, easily winning re-election by more than 25 points in 2006. She stepped down in 2009 to join President Barack Obama's cabinet as secretary of homeland security, overseeing border security, ramped-up immigration enforcement and efforts to prevent terrorism. She served until 2013, when she became UC president.Napolitano said she will take a year sabbatical before teaching, beginning in the fall of 2021, at the University of California, Berkeley's Goldman School of Public Policy, where she is currently a tenured professor.Napolitano was asked by reporters if she would rule out running for public office or accepting a political post or appointment."I have no intention in those regards, but you never say never," she said.___Associated Press writer Jonathan J. Cooper in Phoenix contributed to this report. 3903