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Dr. Anthony Fauci delivered more good news regarding a potential coronavirus vaccine, indicating some Americans could begin getting vaccinated by the end of this month.During an interview with CNN’s Wolf Blitzer, Fauci, the director of the National Institute of Allergy and Infectious Diseases National Institute of Allergy and Infectious Diseases, said it’s possible a vaccine could begin reaching some Americans by the end of the month, but was confident some would begin getting vaccinated by the end of the year.Fauci’s declaration came on the same day Pfizer said that its Phase 3 vaccine candidate was showing an effectiveness of over 90%. Fauci said the announcement was promising, but a few more questions need to be addressed before it is given approval. Fauci said that things like the vaccine’s durability and effect on the elderly are among concerns that still need to be tackled.“We may have doses that we’re able to give to people by the end of November, beginning of December,” Fauci told CNN’s Blitzer. “Now you have to go through the hoops of making sure all of the I’s are dotted and the T’s are crossed about the safety and regulatory aspects of it, but we would be giving vaccine, very likely, by the end of this year. That is good news.”Last month, the FDA put into place guidelines on approving a vaccine, which was more restrictive than what the White House had hoped for. The FDA noted that a vaccine candidate must be at least 50% effective. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit.“In addition to outlining our expectations for vaccine sponsors, we also hope the agency's guidance on COVID-19 vaccines helps the public understand our science-based decision-making process that assures vaccine quality, safety and efficacy for any vaccine that is authorized or approved,” Peter Marks, M.D., Ph.D., director of the FDA's Center for Biologics Evaluation and Research, said.While it is possible some will begin getting vaccinated in the coming weeks or months, questions remain on how soon a majority of the country will have the opportunity to become vaccinated. The first Americans slated to become vaccinated will be health care workers and people with a high risk of coronavirus complications, such as the elderly and those living in assisted living facilities, according to an NPR report.Given that Pfizer’s vaccine candidate is showing a high level of effectiveness, Fauci called the development “extraordinary.”"We know there's light at the end of the tunnel, but that doesn't mean that we're going to give up the important public health measures that we continually still have to do every single day,” Fauci said.While there is urgency for both public health and economic reasons for a vaccine, some experts have expressed concern over the speed of a vaccine and whether the expedited timeline is long enough to demonstrate efficacy.Even though a vaccine could be ready by year’s end, trials will be expected to continue for over a year to monitor for possible side effects.According to the FDA, a typical Phase 3 trial would take one to three years.“NIH is committed to supporting several Phase 3 vaccine trials to increase the odds that one or more will be effective in preventing COVID-19 and put us on the road to recovery from this devastating pandemic,” said NIH Director Francis S. Collins, M.D., Ph.D. “We also know that preventing this disease could require multiple vaccines and we’re investing in those that we believe have the greatest potential for success.”Pfizer said based on current projections, it expects to produce globally up to 50 million vaccine doses in 2020 and up to 1.3 billion doses in 2021. 3823

Do you ever wonder what impact putting your recyclables in the right bin can actually have? For one Colorado city, it’s been huge.At prAna, an activewear business located in Boulder, Colorado, Drew Romano’s biggest concerns are his customers and Mother Nature. Recycling is front and center.“Hey, we're not just throwing your stuff in the landfill; it's actually being recycled,” says Romano about the company.Most of prAna‘s shipping supplies are recyclable. As for the plastics bags that hard to recycle, prAna partnered with a company to make sure they don't end up in the landfill.“We wanted to make sure that we can strive to be as zero waste as possible,” says Ramano.It's part of the city’s Universal Zero Waste Ordinance, which requires businesses to recycle and compost.  Environmental manager Kara Mertz, who works for the City of Boulder, says in just one year, the effort is paying off. The city is now saving more than half of its trash from going to the landfill.Mertz says they used this video to show residents how to recycle. Then, they made it easy for residents to do it, by placing bins with clear and identical signage across the city.“I think making it easy and accessible to everyone is really the key,” says Mertz.Mertz says it's something we can all do, no matter where we live.“We do believe that over time people will get more and more used to it,” Mertz says. “It'll become second nature, and then all of that material, once it's sorted properly, can be put in the correct bins.” 1520

Doorbusters have been replaced with delivery, and early store hours are now early-season discounts. COVID-19 has infected Black Friday.Less than one-third (32%) of holiday shoppers plan to do the majority of their gift shopping in-store this year, down from 37% last year, according to NerdWallet’s 2020 Holiday Shopping Report. Many retailers responded by offering early holiday shopping specials with low-price guarantees to encourage you to buy now without the worry of missing a better deal later.What are Black Friday 2020 store hours?For those of us who want to do some in-store shopping on Black Friday, here are the currently announced store hours, in local time. Always check with your nearby store to confirm and find out if it has any COVID-19 safety measures or restrictions.Best Buy: Black Friday store hours will be from 5 a.m. to 10 p.m.BJ’s Wholesale Club: Will open normally from 8 a.m. to 9 a.m. for Senior Hour and at 9 a.m. for all members. Check with your local club for extended hours.Dick’s Sporting Goods: Most stores will open at 5 a.m.Michaels: Open from 7 a.m. to 10 p.m.Office Depot and OfficeMax: Most stores will be open from 8 a.m. to 8 p.m.Old Navy: Open from 12:01 a.m. until 11 p.m.Walmart: Deals will be available in stores at 5 a.m. on Black Friday.Check with your local store for Black Friday hours:Academy Sports + Outdoors.Banana Republic and Gap.Bath & Body Works.Costco.Kohl’s.Lowe’s: Most stores are operating under normal hours, but check to be sure.Nordstrom.Target: Most stores are closing at 10 p.m., but check to be sure.Ulta Beauty.Which stores are closed on Thanksgiving?In recent years, Black Friday sales extended to Thanksgiving Day. As many retailers launched Black Friday discounts even before the end of October, some of those same stores are closing on Thanksgiving.Here’s a list of retailers that have announced they’ll be closed on Thanksgiving 2020:Bath & Body Works.Bed Bath & Beyond.Best Buy.BJ’s Wholesale Club.GameStop.Kohl’s.Michaels.Office Depot and OfficeMax.Target.Ulta Beauty.Walmart.How can you shop Black Friday online?Despite being sued by the U.S. Department of Justice for allegedly acting as a monopoly, Google is expanding its holiday shopping capabilities. The all-knowing, all-seeing Google now has a price comparison engine allowing you to see if the price you’re offered on a product is “high, low or typical” compared with other prices online and in local stores.Google will also compare shipping costs and options, as well as nearby curbside and in-store pickup. There’s a notification function to let you know when a better price becomes available.Here are a few other online Black Friday shopping tips:The supply chain has had its share of roadblocks this year. To mitigate potential delays, online shoppers should place their orders as soon as possible.Online flash sales are frequently occurring, and though the prices are often incredible, many of these events feature items in minimal quantities. Avoid disappointment: Prepare to see an “item sold out” message almost as soon as the discount starts.Browse Amazon’s coupons page for deals you may have previously missed. On the day we checked, the discounts were modest, but that may change as we approach Black Friday. Some coupons may be valid only for Prime members.And remember, Cyber Monday is still on the calendar following Thanksgiving week, just in case you still have room in your budget for some additional holiday shopping.More From NerdWalletHow to Get the Best Apple Black Friday 2020 DealsIPhone Black Friday 2020 Deals: Are They Worth It?Cell Phone Black Friday 2020 Deals: Are They Worth It?Hal M. Bundrick, CFP is a writer at NerdWallet. Email: hal@nerdwallet.com. Twitter: @halmbundrick. 3762

EL CAJON (CNS) - A Santee man accused of in the death of his infant daughter pleaded not guilty today to charges of murder and child abuse. Daniel Charles Marshall, 34, was arrested and charged last week in connection with the April 25 death of 7-month-old Hailey Marshall.Paramedics responding to a medical emergency call in the 8600 block of Paseo Del Rey in Santee on April 22 found the child in medical distress, Lt. Thomas Seiver said. She was pronounced dead at a hospital three days later of injuries that included skull fractures, prosecutors said.The circumstances of the death ``warranted further investigation, resulting in the (sheriff's) child abuse unit responding,'' according toSeiver. ``As the investigation progressed, the homicide unit responded and assumed responsibility of the investigation.'' Marshall is being held in lieu of million bail. 874

Does undocumented immigration lead to more violent crimes? A study looking at the increase of illegal immigrants over 24 years says no.There's a stigma linking violent crime with illegal immigrants and part of that has to do with the spotlight on MS-13 gang arrests across the country and specifically in Lake Worth. But, a state-by-state study says an increase in undocumented immigration actually makes communities safer.The study was conducted by sociologists Michael Light of the University of Wisconsin at Madison and Ty Miller of Purdue University.The FBI's Uniform Crime Report statistics show Florida's violent crime rate over time and statistics from the Pew Research Center show the increase in undocumented immigrants.The study looked at those statistics from 1990 to 2014. In those 25 years, Florida's undocumented immigration was at its lowest in 1990 and its violent crime rate for those years was at its highest. Fast forward to 2007, the undocumented immigration population peaked in the state, and the violent crime rate had dropped by 40 percent and continued to decrease. The study echoes what many immigration advocates argue. "We don’t see a large criminal underground in Lake Worth. What we see are families struggling to get by," said Tim Gamwell, Executive Director of the Guatemalan-Maya Center which helps immigrant families. Big dreams hang up on the walls of the Escuelita Maya in Lake Worth, an after-school and VPK program run by the center.Hopefully, he is going to have a better life than other kids in my country," said Esmeralda about her son.Esmeralda came to the United States when she was five to escape crime in El Salvador.  "It's not an option to come here and be illegal, it's something that we have to do," she said. Getting involved in criminal activity could mean losing everything you've worked for. Patricia Vargas works with families at the Guatemalan Maya Center and said many are afraid of being deported. Gamwell said in some cases they don't even report when they are victims of crimes. "We've seen a history of that, where people are targeted because they have cash on them on payday," said Gamwell. Gamwell said the focus for the 600 plus families they serve in Lake Worth is making ends meet and providing for their children."The big issues are:  How do I educate my children? how to do I get access to a computer? How am I going to pay the rent this month? Not bailing someone out of jail," added Gamwell.  2559