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CHAPEL HILL, N.C. - This week, we've heard promises surrounding treatment and vaccines related to COVID-19.Now, doctors at the University of North Carolina (UNC) are using next-generation genetic sequencing of the virus causing COVID-19 that can help testing and therapeutics.Dr. Dirk Dittmer, professor of microbiology and immunology at the UNC School of Medicine, has kept a close eye on COVID-19.“We know now more about this virus than any other virus before,” Dittmer told News 3. “The team has been working 24/7 ever since we had the first cases in March.”He and others are looking at how next-generation genetic sequencing can help with tracking mutations of the virus.“What we were looking at using next-generation technology is if the virus changes, who is the first person that had the virus in North Carolina? And, as we accumulated more and more cases, were these the same types of viruses we're seeing anywhere else in the world,” Dittmer said. “Very early on, we were able to show that one of the mutations that have been around in Europe was actually coming to the U.S.”The state-funded study shows this sequencing can help with the accuracy of diagnostic testing and vaccine effectiveness.“We wanted to make sure that the tests that were developed very early on would still work now and next year. The takeaway is they still work,” he said. “One of the worries that people have is that the virus might change, and therefore, today's vaccine might not work next year.”“Studies like this are part of the ongoing quality control and safety monitoring for vaccines,” Dittmer added.News 3 medical expert Dr. Ryan Light said this sequencing can help in the fight against the virus.“We can tell if it's changed a little bit, we can tell where that virus is coming from,” Light said. “It tells us where the outbreak is coming from, where the danger areas are, and it tells us that our therapies are still working.Meanwhile, Dittmer's lab will continue using this sequencing to track the virus through the end of the year.“We're just a little piece of the puzzle that helps every one to get rid of this thing,” he said.This story was first reported by Zak Dahlheimer at WTKR in Norfolk, Virginia. 2211

Bulked-up, mutant “mighty mice” held onto their muscle during a monthlong stay at the International Space Station, returning to Earth with ripped bodybuilder physiques, scientists reported Monday.The findings hold promise for preventing muscle and bone loss in astronauts on prolonged space trips like Mars missions, as well as people on Earth who are confined to bed or need wheelchairs.A research team led by Dr. Se-Jin Lee of the Jackson Laboratory in Connecticut sent 40 young female black mice to the space station in December, launching aboard a SpaceX rocket.In a paper published in the Proceedings of the National Academy of Sciences, Lee said the 24 regular untreated mice lost considerable muscle and bone mass in weightlessness as expected — up to 18%.But the eight genetically engineered “mighty mice” launched with double the muscle maintained their bulk. Their muscles appeared to be comparable to similar “mighty mice” that stayed behind at NASA’s Kennedy Space Center.In addition, eight normal mice that received “mighty mouse” treatment in space returned to Earth with dramatically bigger muscles. The treatment involves blocking a pair of proteins that typically limit muscle mass.A SpaceX capsule brought all 40 mice back in good condition, parachuting into the Pacific off the California coast in January. Some of the ordinary mice were injected with the “mighty mice” drug after returning and quickly built up more muscle than their untreated companions, Lee said.The scientists completed the experiment just as the coronavirus was hitting the U.S.“The only silver lining of COVID is that we had time to write it up very intensively” and submit the results for publication, said Dr. Emily Germain-Lee of Connecticut Children’s Medical Center, Lee’s wife who also took part in the study. Both are affiliated with the University of Connecticut.While encouraged by their findings, the couple said much more work needs to be done before testing the drug on people to build up muscle and bone, without serious side effects.“We’re years away. But that’s how everything is when you go from mouse to human studies,” Germain-Lee said.Lee said the experiment pointed out other molecules and signaling pathways worth investigating — “an embarrassment of riches ... so many things we’d like to pursue.” His next step: possibly sending more “mighty mice” to the space station for an even longer stay.Three NASA astronauts looked after the space mice, performing body scans and injections: Christina Koch and Jessica Meir, who performed the first all-female spacewalk last fall, and Andrew Morgan. They are listed as co-authors.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2835

CAMPO, Calif. (KGTV) -- A man was arrested after reportedly assaulting two Border Patrol agents as they attempted to arrest him for trying to smuggle people into the U.S. According to the agency, the incident happened around 1:17 a.m. Tuesday as agents patrolled Interstate 8 in Campo. Agents tried to stop a 2007 Ford F-350 near Kitchen Creek Road when the driver took off, leading agents on a high-speed chase. RELATED: 14-year-old tried to smuggle meth strapped to body, CBP saysAccording to Border Patrol, agents successfully deployed a tire deflation device, forcing the vehicle to stop a short distance later, but the driver got out and fled on foot. As agents searched for man, he reportedly jumped out of a nearby bush, tackling one of the officers to the ground. A second agent also responded to the scene, struggling with the suspect as well. Inside the F-350, agents found three men and one woman, all Mexican nationals in the U.S. illegally. They were all taken to a Border Patrol station for processing and the suspect, identified as a 37-year-old U.S. citizen, was arrested. RELATED: Woman tries to smuggle meth with 7-year-old in car, Border Patrol says“The Border Patrol like any Law Enforcement job is inherently dangerous. The Border Patrol is comprised of a highly trained / multi-disciplined work force. Our agents are trained and equipped to properly confront any situation they may encounter in the field,” said San Diego Sector Acting Division Chief Patricia McGurk-Daniel. “The ambush and assault of our agents will not be tolerated and this case will be prosecuted to the fullest extent of the law in order to protect our workforce and the community.” 1684

CALEXICO, Calif. (KGTV) — A man was airlifted to the hospital Sunday after illegally climbing over a section of Calexico's border and falling.The man, who U.S. Customs and Border Protection said had crossed over illegally sometime just after 8 p.m., broke both of his legs and sustained a back injury from the 30-foot fall from atop the border wall.Video shows the man climbing over and falling to the ground, where he lay motionless.RELATED: Congress watchdog: Border wall may cost more, take longerBorder officials said they found him behind the nearby Gran Plaza Outlet Mall at about 9 p.m.Agents on the scene provided the man with first aid and called in emergency responders, who took the man to a Palm Springs medical center.El Centro Sector Border Patrol released the video on Twitter this week, reminding the public of the danger of attempting to climb the border wall. 890

CHANDLER, Okla. – Investigators say they were able to use DNA from a discarded cigarette butt to crack a 33-year-old cold case.The Oklahoma Attorney General's Office says the cigarette butt and latent prints were collected at a rest stop where Paul Aikman was found brutally stabbed to death in September of 1985.A DNA profile was developed from one of the cigarette butts, but the Lincoln County case eventually went cold.Last year, however, forensic scientists notified agents that they had found a potential DNA hit in the national DNA database. The DNA matched 55-year-old Earl Wilson, who is currently incarcerated in Oklahoma Department of Corrections custody for unrelated crimes.Criminalists say they then matched a print taken from the crime scene to Wilson.Attorney General Mike Hunter has now filed first-degree murder charges against Wilson.“Advances in DNA technology are allowing authorities to take another look at these difficult cases,” said Hunter. “Just because cases go cold doesn’t mean someone shouldn’t be held responsible, even after three decades.”The director of the Oklahoma State Bureau of Investigation, Ricky Adams, says Aikman’s family has suffered for 35 years, not know who was responsible for his murder.“35 years have passed, but we have not forgotten about Paul,” said Adams. “Thanks to science and determined police work by OSBI agents and our Cold Case Unit, we are pleased to announce that the suspect in Paul’s murder has been identified. I would like to give thanks Attorney General Hunter and his staff for taking this case, filing a murder charge and giving a voice to Paul and his family.” 1641