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WASHINGTON, Dec. 7 (Xinhua) -- Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study published Wednesday in the Journal of Neuroscience. The findings could one day aid in the development of new drugs that enhance cognitive function in older adults.Aging-related memory loss is associated with the gradual deterioration of the structure and function of synapses (the connections between brain cells) in brain regions critical to learning and memory, such as the hippocampus.Recent studies suggested that histone acetylation, a chemical process that controls whether genes are turned on, affects this process. Specifically, it affects brain cells' ability to alter the strength and structure of their connections for information storage, a process known as synaptic plasticity, which is a cellular signature of memory.In the current study, Cui-Wei Xie, of the University of California, Los Angeles, and colleagues found that compared with younger rats, hippocampi from older rats have less brain-derived neurotrophic factor (BDNF) -- a protein that promotes synaptic plasticity -- and less histone acetylation of the Bdnf gene. By treating the hippocampal tissue from older animals with a drug that increased histone acetylation, they were able to restore BDNF production and synaptic plasticity to levels found in younger animals."These findings shed light on why synapses become less efficient and more vulnerable to impairment during aging," said Xie, who led the study. "Such knowledge could help develop new drugs for cognitive aging and aging-related neurodegenerative diseases, such as Alzheimer's disease," she added.

SAN FRANCISCO, Oct. 14 (Xinhua) -- Google on Friday announced to shut down the highly-controversial social networking product Google Buzz, along with several other services in the coming weeks.On the company's official blog, Google announced the death penalty to its code search engine, Buzz, Jaiku which let users send updates to friends, the Google personalized homepage feature iGoogle, and the University Research Program for Google Search.The shut-downs came as part of Google's housecleaning effort announced in early September, in which the company said it will shut down a number of products and merging others into existing products as features."Changing the world takes focus on the future, and honesty about the past. We learned a lot from products like Buzz, and are putting that learning to work every day in our vision for products like Google+. Our users expect great things from us; today's announcements let us focus even more on giving them something truly awesome," said Google in the blog post.Google Buzz, a social networking and messaging tool integrated into Gmail service, has been widely criticized for privacy concerns and held back the search giant from expanding its businesses to the social networking space.After Buzz, Google launched Google+ in June, which has been receiving a good response and passed the 40 million user mark, the company's chief executive officer Larry Page said Thursday.

SANTO DOMINGO, Jan. 11 (Xinhua) -- The Dominican Republic and Haiti Wednesday launched a joint plan aimed at eliminating cholera, which has claimed more than 7,000 lives in both countries since October 2010.The efforts were backed by the World Health Organization (WHO), the Pan American Health Organization (PAHO), and the United Nations International Children's Emergency Fund (UNICEF), Dominican officials said.The plan, "Call to action: the Hispaniola without cholera", aims to improve sanitary and living conditions of the Haiti people who face herculean reconstruction work following a devastating earthquake in the country on Jan. 12, 2010, that killed 220,000 people and displaced over 1 million.Cases of cholera, an infection that causes severe diarrhea that can lead to dehydration and death, first appeared in Haiti in October, 2010.The epidemic has so far killed more than 7,000 people and left nearly 500,000 more sick in Haiti.It also killed 135 people in the Dominican Republic as of September 2011, according to Dominican health authorities.Some 500 million U.S. dollars will be invested in projects related to sanitization and the construction of infrastructure that has to do with waterworks in both nations in the long term.

BEIJING, Nov. 28 (Xinhuanet) -- The U.S. FBI and police in the Philippines have arrested four alleged hackers in Manila with connections to a terrorist group in Saudi Arabia, according to media reports Monday.The four who were arrested last Wednesday hacked into AT&T Inc.'s phone systems as part of a plan to funnel money to a Saudi-based terror group, the reports said.The hackers, according to the investigators, worked for a group that helped finance a deadly 2008 terrorist attack in Mumbai, India.Investigators also said the hacking cost AT&T around 2 million U.S. dollars. And an AT&T representative told Reuters that it "ended up writing off some fraudulent charges that appeared on customer bills" but did not comment on the 2 million dollars figure."AT&T and its network were neither targeted nor breached by the hackers," AT&T spokeswoman Jan Rasmussen said. "AT&T only assisted law enforcement in the investigation that led to the arrest of a group of hackers."

WASHINGTON, Sept. 30 (Xinhua) -- At least 15 people have been killed amid 84 sickened in 19 states in listeria outbreak traced to Colorado cantaloupes, making it the most deadly U.S. outbreak of food-borne infection since 1998, the Centers for Disease Control and Prevention (CDC) said Friday.Of the 15 victims, five were in New Mexico, three in Colorado, two in Texas, and one each in Kansas, Maryland, Missouri, Nebraska and Oklahoma. Health departments in Wyoming and Kansas have said they are investigating additional deaths that may be connected to the outbreak.The previous toll announced on Tuesday was 13 dead and 72 sick.The Food and Drug Administration on Sept. 14 warned consumers not to eat cantaloupes from Colorado's Rocky Ford region shipped by Jensen Farms. The cantaloupes with the brand name Rocky Ford were distributed from July 29 to Sept. 10 in at least 17 states."Even if some of the cantaloupe has been eaten without becoming ill, dispose of the rest of the cantaloupe immediately. Listeria bacteria can grow in the cantaloupe at room and refrigerator temperatures," the CDC said.Listeria is a common bacterium that typically causes mild illness in healthy people, but can cause severe illness in older people and those with compromised immune systems. It also can cause miscarriages and stillbirths in pregnant women and severe infections in new babies.Listeria infections lead to about 1,600 serious illnesses each year and about 260 people die, according to the CDC.The CDC estimates that about 48 million people in the U.S. each year get sick from tainted food, with about 128,000 hospitalized and 3,000 deaths.

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