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WASHINGTON, Dec. 7 (Xinhua) -- The use of two drugs never tried in combination before in ovarian cancer resulted in a 70 percent destruction of cancer cells already resistant to commonly used chemotherapy agents, say researchers at Mayo Clinic in Florida.Their report, published on-line Wednesday in Gynecologic Oncology, suggests that this combination, ixabepilone and sunitinib, might offer a much needed treatment option for women with advanced ovarian cancer.Neither drug is approved for use in ovarian cancer. Ixabepilone is a chemotherapy drug that, like other taxane drugs, targets the microtubules and stops dividing cells from forming a spindle. It has been approved for use in metastatic breast cancer. Sunitinib, approved for use in kidney cancer, belongs to a class of tyrosine kinase inhibitors that stops growth signals from reaching inside cancer cells.When caught at late stages, ovarian cancer is often fatal because it progressively stops responding to the chemotherapy drugs used to treat it."Women die from ovarian cancer because their tumors become resistant to chemotherapy, so a drug that might be able to reduce that resistance -- which may be what this combination of agents is doing -- would be a boon to treatment of this difficult cancer," says study coauthor Gerardo Colon-Otero.The finding also highlights the importance of the role of a molecule, RhoB, that the researchers say is activated by the drug duo. It might be a potential biomarker that may help identify patients who might benefit from such combination therapy, the researchers say.
BEIJING, Jan. 25 (Xinhua) -- China's meteorological authority said Wednesday that most parts of China will continue to be in the grip of cold with temperatures remaining low over the next few days.Snowy weather is forecast to continue in the country's southern regions, and freezing rain is expected to hit parts of Guizhou and Hunan provinces, the National Meteorological Center said in a statement on its website.Parts of the country's northwest areas expected to see light snow or drizzle.Meanwhile, fog will shroud most parts of the country's southern areas Wednesday morning, reducing visibility in parts of Yunnan, Hunan, Jiangxi, and Zhejiang provinces to less than 1,000 meters, while smog is forecast to hit some areas of Jiangsu Province, according to the statement.

BRUSSELS, Oct. 7 (Xinhua) --- The European Commission on Friday gave the green light to Microsoft's acquisition of voice and video communication provider Skype, thus removing the last hurdle in the process.According to a statement released by the Commission, "the deal would not significantly impede effective competition in the European Economic Area (The EU plus Iceland, Lichtenstein and Norway) or any substantial part of it."The Commission explained that it found that in the area of consumer communications, the parties' activities overlap in video communications, where Microsoft is active through its Windows Live Messenger.However, the Commission considered that there were no competition concerns in this growing market where numerous other players, including Google, were present.Skype was bought by eBay in 2005 at the price of 4.1 billion U.S. dollars, and sold out at 2.75 billion U.S. dollars in 2009. Microsoft declared to take over Skype at a cost of 8.5 billion dollars on May 10, 2011.
BEIJING, Nov. 16 (Xinhua) -- A senior Chinese commerce official said on Wednesday that the country will work to optimize the import mix of mechanical and electronic products so they can play a bigger role in China's restructuring efforts.Li Jinzao, vice minister of the Ministry of Commerce, made the remarks at a forum of the ongoing 13th "China Hi-Tech Fair" in Shenzhen.His remarks echoed a guideline issued in March on promoting the imports of mechanical and electronic products during the 2011-2015 period, in which China pledged efforts to encourage the imports of high-tech products.Li said that China will improve existing policies to attach more importance to the imports of advanced technology, equipment and components to spur innovation.Meanwhile, he said China will organize more trading events to exchange and cooperate with international businesses, and will continue to push the United States and European countries to ease restrictions on civil high-tech exports to China.
UNITED NATIONS, Jan. 24 (Xinhua) -- China welcomes and supports all efforts and measures that would break the current deadlock of the Palestinian-Israeli negotiation and relaunch their dialogues, Chinese UN ambassador Li Baodong said here Tuesday.Li made the remarks when addressing a Security Council monthly open debate on Middle East."The Middle East peace process is currently in a stalemate. China is deeply concerned over the development," Li said."We always maintain that the parties concerned should resolve their disputes through political negotiations under the relevant UN resolutions, the principle of 'land for peace,' the Arab Peace Initiative and the Middle East Roadmap for Peace with the goal of ultimately establishing an independent Palestinian state and two states,Palestine and Israel, living side by side in peace," he said. China appreciates the efforts made recently by Jordan and Quartet of Middle East to facilitate the two parties to have direct contact, said Li, adding "We hope the relevant peace promotion efforts will help resume the Palestinian-Israeli peace negotiation sooner and achieve substantive result. China supports a greater role of the UN in resolving the Middle East issue."Calling the Israeli settlement "a major obstacle" for the resumption of Palestinian-Israel peace negotiation, Li said China is seriously concerned about the recent approval by the Israeli government of plans for expansion of new settlements."China is always against Israeli establishment of Jewish settlements in the occupied Palestinian territory including East Jerusalem. We urge Israel to cease the settlement construction immediately, be prudent in action and work actively in collaboration with the efforts of the international community to promote peace, and create conditions for the resumption Palestinian-Israeli peace negotiation," the ambassador said.China has always supported the Palestinian people in their just cause to restore the lawful rights of the nation, and maintained that establishment of an independent state is the lawful right of the Palestinian people as the basis for the implementation of the "two-state solution""China supports the establishment of an independent Palestinian state that enjoys full sovereignty, with East Jerusalem as its capital and based on the 1967 border. China supports Palestine's membership in the United Nation," Li said.The Syria-Israel track and the Lebanon-Israel track are important component of the Middle East peace process, and play an indispensable role in the overall settlement of the Middle East issue, Li said.China firmly supports the just cause of Syria and Lebanon to maintain sovereignty and territorial integrity, and recover their occupied territoriesChina supports the strategic choice made by Arab states in their pursuit of a comprehensive and lasting peace in the region, Li added.He also called on relevant parties to keep constrained, avoid the escalation of tension in Gaza, effectively implement relevant UN resolutions and fully lift the Gaza blockade.
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