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?Chinese President Xi Jinping (R) meets with Afghan President Hamid Karzai in Shanghai, east China, May 19, 2014. (Xinhua/Yao Dawei)

At the sendoff at Sanya, Xu Hongmeng, a deputy commander of the navy, said the mission was an important part of the efforts to build a new model of relations between China and the United States and their militaries.

"Today the China-U.S. relations have reached a new historical starting point. New realities call for new ways for countries to interact with each other and build new models of relationship," he said, adding that "our leaders, President Xi Jinping and President Barack Obama, set the goal for China and the United States to work together to build a new model of major country relationship."

They compared notes on a number of issues related to regional and international cooperation, including the cooperation within the Shanghai Cooperation Organization (SCO).

While noting China's economic growth, employment and inflation are all within a proper range, Li said risks and challenges are not to be overlooked as downward pressure remains "relatively high".