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A team at the University of Kentucky is researching a possible treatment for COVID-19 and key helpers are three alpacas; Big Boy, Blue Eyes and Emperor.“It’s a powerful technology that we have at UK (University of Kentucky) and it’s something that hopefully we can develop some therapeutics with,” said Wally Whiteheart, a professor in the Department of Molecular & Cellular Biochemistry.Alpacas, along with llamas and camels, make a special kind of antibody called a nanobody. Nanobodies can be useful in cancer research and for other diseases. Researchers, led by Whiteheart and fellow professor Lou Hersh, are working with a nearby ranch to see what impact alpacas could have on COVID-19.“We, in a sense vaccinate them, and this case with viral proteins, and we make nanobodies to those viral proteins,” explained Whiteheart. “We can then go and purify and identify the nanobodies that bind to the virus and then test them to see if they can inhibit viral infection.”Making the nanobodies is just the first step. The team will see which, if any, can block virus infection and those candidates could move on to clinical trials.There’s still a lot of research and testing to go, and also still a lot of hope.“The cool thing which we’re exploring now is the fact that you might be able to use them as a nasal spray and this actually gets them to the place where the virus is affecting lung tissue,” said Whiteheart.This isn’t the first time the trio of alpacas has helped medical research. Big Boy, Blue Eyes and Emperor have contributed to the university’s nanobody research for more than three years. In that time, they have helped researchers generate more than 50 nanobodies to target proteins involved in a variety of human diseases including cancer, diabetes and neurological disorders.This story was originally reported by Alex Valverde on LEX18.com. 1869
A small town in Canada's Saskatchewan province mourned Saturday after a bus carrying a junior hockey team collided with a tractor-trailer, leaving 15 people dead and at least 14 injured."This is a dark moment for our city, our community, our province," Humboldt Mayor Rob Muench said Saturday afternoon at a news conference. "There is no playbook on what to do in cases like this."Members of the Humboldt Broncos hockey team were headed to the town of Nipawin for a playoff game Friday night when the crash happened north of Tisdale, the Royal Canadian Mounted Police said. 581
A report from the Tucson Police Department is revealing new details about the death of Carlos Adrian Ingram-Lopez while in TPD custody in April.The police department began its investigation into the incident hours after it happened on April 21. Nearly two months later, on June 19, the department finished its report and handed it off to TPD Chief Chris Magnus. After a news conference about the incident Wednesday, TPD released the full report to members of the news media.TIMELINE: What happened after Carlos Ingram-Lopez died while in TPD custodyThe report recommends termination for officers Samuel Routledge, Ryan Starbuck, and Jonathan Jackson, who had resigned the day before the investigation was completed.The discipline report focuses on how officers are supposed to treat someone in a state of “excited delirium," how it greatly increased the risk of dangerous physical distress and how the three officers failed to meet their standards and training.The report draws a number of conclusions about the officers involved in the incident. It says:The initial report of Ingram-Lopez's behavior should have prepared the officers to deal with excited delirium before they even saw him.Ingram-Lopez's behavior at the scene made excited delirium very clear.The report documents dates of when the officers had training on excited delirium at the academy and in other training sessions after that.Excited delirium and the likelihood of drug intake make overheating and rapid heartbeat something officers should anticipate.The fact that he was calling for water confirms they should have been more aware of his physical distress.The officers were trained on, and should have been alert to, signs of breathing trouble, like wheezing, and simply saying “I can’t breathe." Ingram-Lopez did both.The officers had been trained on the “recovery position” designed to reduce physical distress on a restrained suspect.One of the officers who arrived later said within 15 seconds, “Shouldn’t he be in the recovery position?” That officer is not being disciplined.The officers put a “spit sock” over Ingram-Lopez's face because of his choking and clearing his throat made them fear he would spit and spread COVID-19. The spit sock was available to officers even before the COVID outbreak.While officers did not use prohibited methods like neck holds, they noted Ingram-Lopez was a large man and one of the officers kneeled on his back for a sustained period.Officer Jonathan Jackson was Lead Police Officer -- slightly more senior than the other officers who first arrived at the scene. He was expected to take command and organize the other officers. The report says he failed to command adequately and organize the police response.Other officers either reacted appropriately or were with the grandmother, where they were not well aware of what was happening with Ingram-Lopez.Overall, the report concluded the officers ignored their training and were unaware or indifferent to Ingram-Lopez's situation and physical distress.Click here to read TPD's full report.KGUN's Craig Smith first reported this story. 3106
A Tennessee woman has called her 6-year-old son's daycare facility negligent after he was left alone outside when it closed early in observance of Veterans Day.Megan Talley, of Parrotsville, Tennessee, told WATE-TV that one of her son's school teachers happened to find him alone and crying outside Precious Memories daycare on Friday afternoon."I almost went into a full blown panic attack," Talley told the TV station. 433
A Phoenix father is accused of using frozen hot dogs to reduce swelling to the legs and backside of his 2-year-old son after he'd abused him.Phoenix police report that on Tuesday they arrested 23-year-old Joshua Junior Rodriguez for child abuse that he allegedly inflicted upon his 2-year-old son on Oct. 11.Police say that after an argument, the boy's mother was packing a bag to leave when she heard "whipping sounds" coming from the garage. When she looked in, she reportedly saw Rodriguez striking their son on the bottom with a strap from a duffel bag.She grabbed the boy away from him and went into the house. However, Rodriguez pushed her away and grabbed the boy again, taking him to the bedroom, removing his diaper and continuing to strike him on the butt.Police say Rodriguez then threw him on the bed and spanked him 23 times, before taking him into the showers where he struck him again when the boy tried to get out.After seeing the injuries he inflicted, Rodriguez allegedly placed a package of frozen hot dogs on his butt to reduce the swelling.He reportedly told the child’s mother, "You're going to get me for child abuse, huh?" He would not allow her to leave home until she agreed not to call the police.During his emotional initial Court appearance, Rodriguez claimed, "these are all false allegations."Police say the boy suffered "extensive bruising" and scratches. 1410