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SAN DIEGO (KGTV) - Five San Diego restaurants are among the best restaurants for a night out, according to a recent survey.Mobile app OpenTable surveyed more than 12 million user reviews to determine the "100 Best Restaurants" for a night out anywhere in the U.S. In San Diego, five made the cut: 324

SAN DIEGO (KGTV) — UC San Diego researchers are testing a technology that's been in development for more than a decade to fight the coronavirus.In lab experiments, "nanosponges" covered in human lung cell membranes and immune cell membranes were found to attract and neutralize the SARS-CoV-2 virus in cell culture, according to a UCSD release. This caused the virus to lose about 90% of infectivity, or its ability to hijack cells and reproduce.The tiny sponges are designed to impersonate and protect healthy cells by soaking up harmful pathogens and toxins, according to Liangfang Zhang, a nanoengineering professor at the UC San Diego Jacobs School of Engineering. RELATED: San Diego company's COVID-19 test gets emergency approvalFor example, the nanoparticle covered in membranes from cell types the virus is known to invade latch on to the virus. This prevent the virus from then entering an actual human cell."Traditionally, drug developers for infectious diseases dive deep on the details of the pathogen in order to find druggable targets. Our approach is different. We only need to know what the target cells are. And then we aim to protect the targets by creating biomimetic decoys," said Zhang.While Zhang has spent the last 10 years developing the technology, his lab turned to using the nano-particle to fight the coronavirus when the pandemic hit.RELATED: Scripps Research's antibodies study shows signs of success against coronavirusNow, the first data on the technology's ability to battle the virus is being released after testing by researchers at Boston University."Another interesting aspect of our approach is that even as SARS-CoV-2 mutates, as long as the virus can still invade the cells we are mimicking, our nanosponge approach should still work. I’m not sure this can be said for some of the vaccines and therapeutics that are currently being developed," said Zhang.UCSD researchers will test the nanosponges’ effectiveness in animal models in the next few months and are moving as fast as possible to eventually test the technology in humans. RELATED: Startup creates mobile COVID-19 testing clinic on wheelsNanosponges have a massive amount of testing ahead before they make it to human tests, Zhang said."I see potential for a preventive treatment, for a therapeutic that could be given early because once the nanosponges get in the lung, they can stay in the lung for some time," Zhang said. "If a virus comes, it could be blocked if there are nanosponges waiting for it."(Read more about the study and nanosponges here.) 2562

SAN DIEGO (KGTV) — UC San Diego says it plans to begin repopulating its campus this summer, with about 30% of courses being held in person this fall.The campus says in-person classes will be limited to less than 50 students per class or 50% classroom capacity, whichever is lower. Any classes with more than 50 students enrolled will be offered remotely.Some classes will also be held in a hybrid format. The fall quarter is set to begin on Sept. 28, with student arrivals to campus being staggered to protect the capacity for testing."We aim to mitigate risk in a way that will allow UC San Diego to provide an environment for learning and offer a university experience that our students expect," said Chancellor Pradeep Khosla. "As one of the nation’s leading research universities, we have risen to meet difficult circumstances and responded with innovation every step of the way."For students attending in-person classes, facial coverings will be required, according to the school. Students will also be tested for COVID-19 monthly and when moving in on campus.UCSD plans to offer regular coronavirus testing to students, faculty, and staff, with higher frequency in testing for those who are at higher risk for infection. The campus says there will be no cost for asymptomatic or symptomatic testing for students, faculty, and staff when done at a UC San Diego Health location or through Student Health Services.“Our adaptive model considers the most current science on transmission and infection risk and will drive our determinations on the testing frequency of our various campus populations,” said project lead Natasha Martin, associate professor of medicine at UC San Diego School of Medicine. “We wanted a simple, easy testing process which can be delivered at scale in the fall to ensure widespread testing for early outbreak detection.“Our simulations indicate that if more than 75 percent of the population were tested per month, we would be able to detect an outbreak before there are 10 detectable infections on campus,” she said.Students aren't thrilled at the impact the coronavirus is having on their college experience."You can't really make new friends and meet new people and do many projects strictly online," Dylan Nelson said. He will be an incoming Junior at UC San Diego. This summer his internship in New York was also put on hold due to the pandemic, but he's finding the silver lining."Fortunately all [my classes are] computer based classes, so a lot of that was going to be online anyway so it's not too hard to adapt," adding, "as a Junior I think it's tough but not the worst, I feel bad for all the Seniors going in right now because you're missing out on potentially really big classes."ABC 10News asked if he would feel comfortable returning to class wearing a face covering, "for me personally no, I think for other people in certain classes they might want the more in person aspect."Nelson is hopeful for the future, saying this to his fellow Tritons, "hang in there and stay safe or this may be even longer than we want it to be." 3079

SAN DIEGO (KGTV) - When it comes to wrong-way crashes in San Diego County, 2018 is off to an unfortunate start.There have been numerous wrong-way vehicle crashes around the county nearly eight weeks into the new year, and authorities have not been able to pinpoint what exactly is causing an uptick in these types of crashes.According to Caltrans data, from 1995-2012, an average of 23 people died each year in wrong-way crashes on California roadways.San Diego had 13 wrong-way fatalities recorded in 2015 -- the last year Caltrans data was compiled for wrong-way crashes.In 2017, Caltrans launched a two-year pilot program in San Diego and Sacramento that focuses on ways to not only prevent wrong-way crashes but to also alert authorities in the event a vehicle is traveling in the wrong direction.As part of the test program, Caltrans has deployed reflective pavement markings on off-ramps and signs with flashing lights that turn on if a wrong-way vehicle is detected.Caltrans has not yet provided data collected from the program to determine the protective measures' effectiveness.Here's a look at wrong-way crashes on San Diego County roadways in the past 12 months.Feb. 20, 2018: Driver arrested on suspicion of DUI after wrong-way crash-- A driver was hospitalized -- and also arrested -- after police said he was driving in the wrong direction on Fairmount Ave. when he hit another vehicle. STORYFeb. 18, 2018: One dead, five injured in crash at Scripps Ranch-- A 90-year-old woman died and five others were injured after a head-on collision at a Scripps Ranch intersection. STORYFeb. 17, 2018: At least 1 dead in possible head-on crash in Sorrento Valley-- The driver of a Honda driving the wrong way was killed after colliding head-on with a truck on I-5 near Sorrento Valley Road. STORYJan. 31, 2018: Suspected drunken driver crashes head-on into unmarked CBP vehicle-- A woman accused of drunken driving was traveling northbound on southbound Fairmount Ave. when she crashed into an unmarked Customs and Border Protections SUV. STORYJan. 29, 2018: Injuries reported in wrong-way crash on Interstate 5-- A driver traveling the wrong way on I-5 in the National City area crashed into another vehicle, injuring two children. STORYDec. 18, 2017: 2 drivers injured in Tierrasanta wrong-way crash-- A PT Cruiser traveling the wrong way on Tierrasanta Blvd. crashed into a pickup truck, leading to injuries to both drivers. STORYOct. 14, 2017: Driver dies after head-on collision in Escondido-- One person was killed after police said a Saturn veered into the opposite lanes and collided head-on with a Toyota. STORYJuly 8, 2017: One dead in wrong-way I-5 collision in National City-- Two vehicles collided on I-5 in the National City area, killing one person and leaving both vehicles in flames. STORYJuly 7, 2017: 2 killed in wrong-way crash on Interstate 5 in Oceanside-- A Toyota Camry driving the wrong way on I-5 crashed head-on into a Toyota SUV. Both drivers died at the scene, the CHP said. STORYJune 27, 2017: Valley Center head-on collision leaves two dead-- An SUV crossed over the double line on Lilac Road and crashed into a Mercedes, killing two of its occupants. STORYJune 19, 2017: 1 dead, 1 injured after wrong-way head-on crash in Fallbrook-- Authorities say a Honda was going in the wrong direction at a high rate of speed on Via Encinos Drive when it collided with a van. STORYMay 5, 2017: 1 dead, 2 hurt in head-on collision in El Cajon-- A man was killed and two others were injured after a collision on Avocado Avenue. STORYMarch 27, 2017: Wrong-way driver crashes on Coronado Bridge, prompts lane closures-- A suspected DUI driver was driving the wrong way on the Coronado Bridge when she crashed into two other vehicles. STORYFeb. 9, 2017: Wrong-way driver hits cars on northbound I-5 in Chula Vista-- An elderly driver traveling south on northbound I-5 crashed into multiple vehicles. STORYRELATED: Team 10 report: Wrong-way crashes causing concern on San Diego freeways 4012

SAN DIEGO (KGTV) — With schools temporarily closed because of the coronavirus, a Carlsbad librarian is providing the comfort of a library to students one driveway at a time.Calavera Hills Elementary librarian Lindsay Rudy started drive-by storytimes Wednesday, but has already found her schedule filing up with requests."I'm definitely surprised," Rudy said. "It makes my heart so happy."RELATED: San Diego County libraries go digital to fight spread of coronavirusRudy said the service started after she contacted a family and asked if they would be interested in storytime. Soon, others also signaled their interest."It brought me back to feeling like I was right there with them at the school," Rudy said. "The only difference was no hugs."Before school closures hit the Carlsbad Unified School District, Rudy checked out several books from the library to have on hand and to help continue interest for the California Young Reader Medal, a program where students vote for their favorite books.RELATED: Kids can design their own Disney park online with 'Imagineering in a Box'Discussion isn't solely on the plot during storytime. Rudy says the interactions also help spark conversations around life, especially at a time when kids are dealing with a lot of emotions."It really just made me happy we were able to continue that connection," Rudy said. "The biggest part of the job that I love, you have stories that appeal to a kid but also discussion."And while the change has also been sudden for herself, Rudy says CUSD has made the pivot to virtual learning seamless and supportive.RELATED: Woodward Animal Center launches 'critter cam' amid social distancingSo she can focus on feeding hungry readers new stories — at a safe distance."There's always, even in an age of technology, there's always a place for a book and always a place for a library," Rudy said.You can follow along with Rudy's drive-by storytime project on Instagram here. 1951