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SAN DIEGO (KGTV) - The City of San Diego has closures planned for Monday, February 19 as the nation observes Presidents Day.Trash pickup will be on a normal schedule for City of San Diego customers served by the City’s Environmental Services department.Parking meters, time restrictions for parking and yellow zones will not be enforced.WHAT’S CLOSED: 359
SAN DIEGO (KGTV) — The back-to-back announcements of promising clinical trial results from Pfizer and Moderna may usher in a new era for vaccine technology.Both companies have candidates that rely on a new kind of vaccine strategy: RNA. Preliminary data show both candidates are more than 90 percent effective.On the surface, the vaccine candidates look like any other you’ve taken. They work by training your body to build up defensive weapons against a virus, like antibodies and T-cells.But instead of training your body by introducing a killed virus or a fragment of a virus, the vaccines from Moderna and Pfizer introduce a set of instructions called messenger RNA enclosed in a little blob of fat.“The key concept of RNA is that they’re messages, and they’re meant as short-term messages,” said Dr. Shane Crotty of the La Jolla Institute for Immunology.Crotty said there are 5,000 to 10,000 messages within a cell at any given time.Once administered, the mRNA in the vaccine instructs some of your cells to make the coronavirus’ signature spike protein. The spike protein on the surface of the coronavirus allows it to infiltrate and hijack cells.Even though the spike protein is just one of about 25 genes the virus has, preliminary results from the clinical trials suggest it is enough material to train the immune system without making the recipient sick.Crotty likened the process of training the immune system to spotting a sedan. If the coronavirus is a car, the spike protein might be the door.“There's no way that car door could turn into a whole car, but it's enough of a piece of a car for your immune system to recognize that car if it saw it again,” he said.Scientists started by sequencing the virus’ DNA from a sick patient, then encoding that genetic sequence into an mRNA instruction molecule that can be read by the manufacturing part of cells.From there, Dr. Crotty said it’s a bit like the messenger app Snapchat.The mRNA gets injected into the body, sending temporary instructions to your cells that last for a while, then disappear. mRNA does not genetically modify cells, he stressed.“They’re around as messages for some period of time and then they go away, and the cells get back to their normal job of reading their own messages instead of reading the messages you’re injecting in the vaccine,” he said.The concept has been around since the 1990s, but there are currently no RNA vaccines on the market for any pathogen, so Dr. Crotty said it’s hard to estimate how long their protective effects will last.Some vaccines offer a lifetime of protection, like the measles vaccine. Others offer decades of protection. The flu vaccine only lasts about six months.Dr. Crotty said the length of protection depends on how fast the virus mutates and how long the immune cells survive in the body.But even if the COVID-19 vaccine turns out to need an annual update, he’s optimistic. The best feature of RNA vaccines is that they can be quickly reprogrammed.Both Moderna and Pfizer are still in their Phase 3 trials, but they expect to finish them by December. Together, they estimate they’ll have enough doses for about 35 million people by the end of this year, primarily for healthcare workers and high-risk individuals. 3250

SAN DIEGO (KGTV) — Summer is right around the corner, San Diego.For younger San Diegans, that means week of adventure and learning at summer camp! And there's something for every interest around San Diego County. Whether it's a traditional day camp with fun activities or something specific (did someone say Circus Camp?)RELATED: Events to enjoy with your toddler in San DiegoHere's a look at a variety of camps — specialty or traditional — around the county this summer:Summer Critter CampWhere: Helen Woodward Animal Center; When: June 10 - Aug. 30Kids will get to experience animal encounters and summer camp activities, animal-themed games, crafts, songs, and get a free Critter Camp t-shirt.YMCA Overnight and Day CampsWhere: Various locations; When: June - AugustYMCA branches across San Diego County offer up a variety of day and overnight camps, from traditional to specialty, and camps just for sports, leadership, adventure, and more.Mesa Rim Climbing CampWhere: Mesa Rim locations; When: March - AugustKids can hit the ropes at Mesa Rim's two San Diego locations, learning yoga, top roping and bouldering skills, or enjoying non-climbing activities like a ninja obstacle course, scavenger hunts, and more.San Diego Zoo and Safari Park Summer CampWhere: San Diego Zoo and Safari Park; When: June - AugustCampers will get to enjoy a wide variety of animal adventures at the San Diego Zoo or Safari Park, with options for various grade levels and featuring a variety of exhibits, tours, games, crafts, and more.Girl Scout CampsWhere: Various locations; When: Various datesWhether or not your child is a Girl Scout yet, they can jump into summer day camps, resident camps, weekend camp outs and more, all featuring educational activities and leadership building fun. Circus CampWhere: San Diego Circus Center; When: June 17 - Aug. 9Kids will learn the fundamentals of circus arts at the San Diego Circus Center's summer camp. Everything from aerial tricks, tumbling, juggling, and clowning to help build strength, teamwork, and focus.Wildlife Day CampWhere: Living Coast Discovery Center; When: June 10 - July 26Campers will experience animal encounters, games, arts and crafts, outdoor exploring, and more while learning about wildlife, conservation, and science.Outside the LensWhere: Liberty Station; When: June 21 - Aug. 23Interested in photography? Kids can jump into a variety of digital media camps throughout San Diego County, designed to build photography and filmmaking skills, promote creativity, and encourage collaboration.Science Summer CampWhere: Fleet Science Center; When: June - AugustA variety of science-themed activities await covering STEAM topics, wildlife, energy and physics, coding, space, and much more through experiments and hands-on learning.Youth Programs at La Jolla PlayhouseWhere: La Jolla Playhouse; When: June - JulyChildren will take part in a series of interactive theatre training programs that cover acting, musical theater, stage movement, improvisation, or behind-the-scenes tasks like costumes and props, set design, and technician support. 3098
SAN DIEGO (KGTV) — The North County Transit District announced plans last week to expand the COASTER rail line to the downtown convention center.The San Diego Pathing Study outlined the plan to bring COASTER service to the convention center. The long-term endeavor would extend service from the Santa Fe Depot to the Convention Center. The plan includes an eventual station at the Convention Center.The study is mapped out in near-, mid-, and long-term projects. The convention center extension and station are listed in the plan's mid-term phase, while extending service to a new Amtrak facility in National City for Pacific Surfliner operations falls in the long-term phase.The full plan, which includes other rail enhancements and services, would cost about billion."The collaboration on this important study by NCTD and its freight partner represents the b
SAN DIEGO (KGTV) -- The National Weather Service is warning beachgoers ahead of the July 4 holiday about elevated surf and strong rip currents. A beach hazards statement will remain in effect until Friday at 3 a.m. According to the National Weather Service, waves will reach three to six feet accompanied by dangerous rip currents. “Remember to swim near a lifeguard if going out in the ocean,” said 10News meteorologist Megan Parry. RELATED: Check your Fourth of July forecastTidal overflow is also possible is areas prone to flooding, such as low-lying areas. “Tidal overflow will be possible in low lying areas during high tide between 9pm and midnight each night - keep that in mind when setting up to watch any fireworks shows during the day as the high tide moves in it may push you back by the night,” Parry added. Swells are expected to build again Friday through Sunday from Hurricane Barbara. 911
来源:资阳报