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WASHINGTON, Sept. 26 (Xinhua) -- Older people with low blood levels of vitamin B12 markers may be more likely to have lower brain volumes and have problems with their thinking skills, according to researchers at Rush University Medical Center in Chicago.The results of the study will be published Tuesday in Neurology, the medical journal of the American Academy of Neurology.Foods that come from animals, including fish, meat, especially liver, milk, eggs and poultry are usual sources of vitamin B12.The study involved 121 older residents of the south side of Chicago over the age of 65. They had blood drawn to measure levels of vitamin B12 and B12-related markers that can indicate a B12 deficiency. The same subjects took tests measuring their memory and other cognitive skills.An average of four-and-a-half years later, MRI scans of the participants' brains were taken to measure total brain volume and look for other signs of brain damage.Having high levels of four of five markers for vitamin B12 deficiency was associated with having lower scores on the cognitive tests and smaller total brain volume."Our findings definitely deserve further examination," said Christine Tangney, associate professor at Rush University Medical Center and lead author of the study. "It's too early to say whether increasing vitamin B12 levels in older people through diet or supplements could prevent these problems, but it is an interesting question to explore. Findings from a British trial with B vitamin supplementation are also supportive of these outcomes."On the cognitive tests, the scores ranged from -2.18 to 1.42, with an average of 0.23. For each increase of one micromole per liter of homocysteine -- one of the markers of B12 deficiency -- the cognitive scores decreased by 0.03 standardized units or points.Tangney noted that the level of vitamin B12 itself in the blood was not associated with cognitive problems or loss in brain volume. "Our findings lend support for the contention that poor vitamin B12 status is a potential risk factor for brain atrophy and may contribute to cognitive impairment," said Tangney.

WASHINGTON, July 12 (Xinhua) -- Two U.S. astronauts stepped out the International Space Station on Tuesday to retrieve a failed ammonia pump, which is the last spacewalk of the shuttle era, NASA announced.Space station astronauts Mike Fossum and Ron Garan completed the six-hour, 31-minute spacewalk at 3:53 p.m. EDT (1953 GMT). The duo retrieved a pump module from an external stowage platform on station and store it in shuttle Atlantis' cargo bay for return to Earth.The pump module failed in 2010, shutting down half of the space station's cooling system. Engineers will evaluate the module to determine the cause of the failure and plan to refurbish it for use as a spare.The astronauts also attached a Robotic Refueling Module experiment to the space station, which aims to test technologies for repairing and refueling satellites in space.It was the 249th spacewalk by U.S. astronauts and the 160th spacewalk in support of space station assembly and maintenance, totaling 1009 hours, nine minutes.Atlantis lifted off on Friday morning from Kennedy Space Center in Florida, on the 135th and final flight in NASA's shuttle program. Its return to the earth later this month will mark the end of the 30-year shuttle program.

BEIJING, Aug. 23 (Xinhuanet) -- More than 90 percent of U.S. heart attack patients who need the lifesaving procedure receive it within just 90 minutes of being admitted to the hospital, according to a study released Monday in the journal Circulation.The study on the American Heart Association's journal shows that in 2010, 91 percent of heart attack patients who needed angioplasty were treated within the 90-minute window. While in 2005, 44% were.Researchers analyzed data on more than 300,000 such patients who underwent emergency angioplasty between January of 2005 and October of 2010.The improvement is the result of a nationwide effort between federal agencies, health care organizations and health care providers to improve heart attack care and outcome, said study author Dr. Harlan M. Krumholz, a professor of medicine and epidemiology and public health at Yale University School of Medicine, according to U.S. News reports.

CANBERRA, Sept. 7 (Xinhua) -- A team of Australian and U.S. scientists on Wednesday said they discovered a genetic defect, which can lead to Leigh syndrome, a rare disorder which affects the central nervous syndrome.The scientists tested more than 1000 genes by encoding proteins active in two individuals who suffer from the illness. They used a new technique known as next-generation DNA sequencing to examine the genes.The gene they discovered encodes an enzyme which is found in the mitochondria which are subsets of cells. Without this enzyme the mitochondria do not translate proteins efficiently, and this then causes Leigh syndrome.According to David Thorburn, from the Murdoch Children's Research Institute in Melbourne, the discovery shows the enormous potential of the new technology."These findings demonstrate the ability of sequencing technologies to improve diagnosis," Professor Thorburn said in a statement released on Wednesday."Although it isn't clear in the case of Leigh syndrome whether the precise molecular diagnosis will necessarily lead to therapies, the current findings represent a meaningful service."He added that diagnosis of the disease along with its specific genetic cause can also be informative about the risk a couple has of having another affected child. The diagnostic information can help in decisions about whether and how to pursue alternative means of having children, for instance through the use of donor sperm or eggs.The research team consisted of scientists from Australia's Murdoch Institute as well as the Broad Institute in the U.S.In Leigh syndrome, infants are born apparently healthy only to develop movement and breathing disorders that worsen over time, often leading to death by the age of three. The problem is that the mitochondria responsible for powering their cells cannot keep up with the demand for energy in their developing brains.

CANBERRA, Sept. 9 (Xinhua) -- Australia on Friday launched the first national study to find out whether low to moderate levels of alcohol drank by pregnant women are harmful or not to an unborn child, hoping to provide a clear indication about the safe amount of alcohol for pregnant women.The Murdoch Children's Research Institute in Melbourne, which commissioned the study, is recruiting 2000 pregnant women who will be quizzed throughout their pregnancy about their drinking habits, general health and diets.Their babies will then undergo medical checks, when they turn one and again at two to see if their brains, development and behavior was affected by alcohol consumed by their mums.According to lead researcher associate professor, Jane Halliday, while there was solid evidence about the dangers of heavy drinking for an unborn baby, it was not known if there was a safe amount of alcohol pregnant women could drink.She said the study hoped to shed light on the best approach to alcohol use during pregnancy."The problem is that for about half of women that get pregnant it is unplanned, and a lot of women are drinking around the time they get pregnant and may drink for the first month or so and that creates a lot of anxiety," Assoc Prof Halliday said in a statement."From the few international and Australian studies there's conflicting evidence as to whether there's an adverse effect."We firmly believe that no drinking is the safest option, but our main aim is to provide an evidence base to the policy and answer questions about individual risks."The study came after research by the University of Newcastle published in 2010 revealed 80 percent of Australian women drank during pregnancy.