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SAN DIEGO (CNS) - The Collaborative Clinical Trials Unit at UC San Diego has been selected to lead and administer an international seven-year, million grant for HIV/AIDS clinical trials.The National Institutes of Health selected UCSD, along with other American, South African and Indian research hospitals, as part of its seven-year HIV/AIDS funding renewal. Every seven years, NIH competitively renews its funding of the HIV clinical trials networks operating in the United States and internationally.During the current application process, the UC San Diego AntiViral Research Center, University of Colorado Hospital, Houston AIDS Research Team and Durban International clinical research sites were chosen to work collaboratively on research priorities for the NIH/National Institute of Allergy and Infectious Diseases HIV/AIDS Adult Therapeutics Clinical Trials Network.The Chennai Antiviral Research and Treatment Center, University of Southern California and University of Miami clinical research sites were also chosen to join UCSD to serve as qualified reserve or protocol-specific sites as needed for future clinical trials."UC San Diego has helped shape HIV/AIDS research and treatment through innovative research since the inception of the adult and pediatric therapeutic clinical trials networks in 1986," said principal investigator Dr. Constance A. Benson, director of UCSD's Antiviral Research Center."Together, the seven clinical research sites selected by the NIH for the HIV therapeutic clinical trials network bring together a wealth of scientific expertise, experience and the high quality performance required to conduct complex clinical trials," she said.Abouty 38 million people are living with HIV/AIDS globally, with 1.7 million acquiring HIV in 2019 alone. In the United States, 1.2 million people are living with the virus.The UCSD-led clinical trials unit serves several regions in the United States burdened by chronic and new HIV infections as well as global regions impacted by both HIV and tuberculosis.The unit will investigate therapeutic strategies aimed at a cure for HIV, including evaluating viral persistence, researching antibody approaches to treatment and prevention and investigating treatment of inflammation and its impact on HIV comorbidities.In addition, investigators will study new drugs including long-acting drug formulations for HIV treatment and prevention, HIV-related coinfections and comorbidities -- including metabolic and end organ complications and a hepatitis B cure, as well as the treatment and prevention of tuberculosis, including TB preventive vaccines, in persons with mono- and HIV-coinfection."We are honored to lead a talented pool of investigators in a common goal of advancing research that clinically benefits people living with HIV," Benson said. 2830

SAN DIEGO (CNS) - The Mexican government issued a statement Sunday expressing regret over Friday's shooting death of one of its citizens by a U.S. Border Patrol agent near the U.S. port of entry in San Ysidro.The office of the Consulate General of Mexico in San Diego said it issued the statement on behalf of the Mexican government."The Mexican government regrets the use of lethal force against a Mexican national and will follow up on his death at the hands of federal immigration authorities," the statement said.San Diego homicide detectives are investigating the shooting, which occurred close to the international border near the Las Americas Premium Outlets mall on Camino De La Plaza at 5:45 p.m. Friday, according to Aaron Heitke, chief patrol agent of the Border Patrol's San Diego Sector.Paramedics pronounced the suspect dead at 6:25 p.m., Heitke said.RELATED:Man shot, killed by Border Patrol agent near Las Americas Premium OutletsBorder Patrol says Mexican national shot to death was trying to enter U.S. illegallyThe man was involved in an altercation with the agent on federal property, but it was unclear what prompted it, Lt. Andra Brown of the San Diego Police Department told reporters at the scene."During the arrest, an altercation ensued and the agent discharged his firearm, wounding the man, who was later identified as an adult Mexican national," Heitke said."Nearby agents and law enforcement personnel responded immediately and initiated lifesaving efforts until emergency medical services arrived," Heitke said.The statement from the Consulate General of Mexico in San Diego said it "has taken action to guarantee due process in this case, in light of the fact that the family members of the victim have not been located as of today."The consulate said the San Diego Police Department will be in charge of the investigation, "even though the agents responsible for this incident are Border Patrol officers.""In an unfortunate coincidence, this incident follows another one reported on October 19, in which Mexican national Jose Alfredo Castro Gutierrez lost his life in an altercation with San Diego police officers," the consulate said. "The Mexican government, through the Consulate General of Mexico in San Diego, is following both cases closely and has requested local authorities to conduct (expeditious,) impartial and transparent investigations to establish the facts and determine where responsibilities lie.""Based on this information, the Mexican Ministry of Foreign Affairs will determine the diplomatic and legal measures to be undertaken in defense of our Mexican nationals," the statement said. "The Ministry of Foreign Affairs deeply regrets the death of the Mexican national and reiterates its absolute commitment to the defense and protection of Mexican nationals abroad."Brown, of the SDPD, said Saturday, "As with any officer or agent- involved shooting that occurs in the city of San Diego, the San Diego Police Homicide Unit was called to the scene to conduct the investigation. It is still early in the investigation, but preliminary information is that the male, a Mexican national, attempted to enter the United States illegally and was confronted by a Border Patrol agent."Brown said the man fought with the agent, who received minor injuries during the incident."The agent fired his duty weapon, striking the male once in the torso," Brown said.The man has been identified, but his name was not immediately released. Neither was the Border Patrol agent's name immediately released."The investigation and review process for an agent-involved shooting are extremely thorough," Brown said. "The U.S. Border Patrol is cooperating with the investigation."When the homicide unit completes their independent investigation, it will be reviewed by the U.S. Attorney's office, Brown said."Customs and Border Protection will continue to fully cooperate with this ongoing investigation," Heitke said. "The specifics of this incident have been shared with the Federal Bureau of Investigation and the Department of Homeland Security, office of the inspector general, along with the Office of Professional Responsibility." 4172

SAN DIEGO (CNS) - The Del Mar Thoroughbred Club announced new and enhanced safety protocols for horses and jockeys Wednesday which will be in effect for the Del Mar race track's 80th racing season which begins July 17.The initiatives include a mandate for a five-person review panel to analyze each horse's racing, medical and training history to ensure each horse is safe to race and a ban on the use of nonsteroidal anti-inflammatory medication fewer than 48 hours before a race or a workout. Previously, NSAIDs were allowed up to 24 hours before a race or workout.The approximately 1,850 horses stabled at Del Mar will also be subject to increased random testing and analysis, veterinary observation and stable security measures to make sure horses are jockeys are following track rules.Riding crops will be prohibited during morning workouts and could be restricted further as the track continues consulting with the California Horse Racing Board and the Jockey's Guild.RELATED: What you need to know about Opening Day at the Del Mar RacetrackIn addition to its enhanced safety protocols, the DMTC announced the creation of an advisory committee of trainers, veterinarians, jockeys, racing surface maintenance experts and track management to continually discuss how to make Del Mar as safe as possible.``Del Mar continues to strive to provide the safest environment possible for our equine and human athletes for both racing and training,'' said DMTC CEO Joe Harper.``We have a responsibility to implement the best practices for safety and welfare and the further responsibility to educate the public about these practices and about the extraordinary levels of care provided to our equine athletes.''The club announced the increased safety measures at a time when horse racing is under unprecedented criticism from animal rights activists. Gov. Gavin Newsom signed a bill last week allowing the CHRB to suspend racing licenses and race days at Santa Anita Park in Arcadia without public notice due to an unprecedented wave of horse deaths and fatal injuries at the track.A total of 30 horses died during Santa Anita's racing season, which ran from Dec. 26-June 23. The deaths led to calls for increased safety measures and an indefinite closure of the track while state officials investigate the cause of the deaths.The DMTC dealt with a similarly deadly racing season in 2016, when 17 horses died during Del Mar's racing season. After remaking its dirt track with the help of race track consultant Dennis Moore and implementing additional safety measures like adding a radiology and ultrasound facility along the track's backstretch, only five horses died during Del Mar's 2017 season and six during its 2018 season.After instituting the changes, Del Mar has been rated one of the safest horse racing venues in the U.S., tallying only 0.79 horse deaths per 1,000 starts last year, according to the Jockey Club Equine Injury Database. According to the DMTC, the national average was 1.68 among tracks that reported their fatal injuries.``Significant thought, due diligence and stakeholder input went into the crafting of the reforms we are implementing this summer,'' said Tom Robbins, the DMTC's executive vice president of racing and industry relations.``All of us recognize our responsibility to ensure the safety and welfare of the horses that race and train here. We are very appreciative of the cooperation from industry stakeholders including our owners and trainers.''The Del Mar Thoroughbred Club is scheduled to begin its summer season July 17 and continue through Sept. 2. Races will be held Wednesday through Sunday each week with a sixth day of racing during the season's final week. 3708

SAN DIEGO (CNS) - The San Diego region's unemployment rate declined to 9% in September, a half-percent drop from the previous month, according to figures released Friday by the state Employment Development Department.According to the EDD, total non-farm employment in San Diego County increased by 11,700 jobs month-over-month -- from 1,372,900 to 1,384,600 -- while farm employment remained unchanged at 9,600.The unemployment rate at this time last year was 2.9%. The region lost 117,700 non-farm jobs and 500 agricultural jobs over the year.According to the San Diego Workforce Partnership, the unemployment numbers are skewed by a large number of San Diegans who have dropped out of the workforce altogether.Whether taking care of aging parents, helping children with school as distance learning continues or concerns over contracting the virus at work, as many as 30,000 people have dropped out of the workforce since February. Unemployment rates typically only count people who are actively looking for work, so these people may not be factored into economic recovery data."While there are lots of production jobs available, San Diegans are still hesitant to go back to work," said Mel Katz, executive officer of Manpower West. "We are seeing hourly wages increasing by two or more dollars per hour to entice workers to leave home and enter the workforce."The region's unemployment rate rose to 15% in May during the COVID-19 pandemic, according to EDD data, while data from the San Diego Association of Governments showed rates of nearly 30% unemployment in May.In September, the state's unemployment rate dropped to 10.8% from 11.6% the previous month, and the nation's decreased to 7.7% from 8.5%.Government jobs led in local monthly gains, with 6,800 jobs added to the region's total. Leisure and hospitality gained 2,500 jobs; educational and health services 2,400; trade, transportation and utilities 1,400; other services 1,100; and professional and business services gained 100.Construction posted the most job losses, with 1,400. Manufacturing lost 900, financial activities 200 and information posted a loss of 100 jobs.Comparing year-over-year, leisure and hospitality continue to top the list in jobs lost, with a total of 52,400 jobs lost since last September -- 38,400 of which came in accommodation and food services.Since the same time last year, government lost 14,200 jobs; trade, transportation and utilities 13,900; educational and health services 10,600; other services 10,300; manufacturing 6,500; construction 4,400; information 3,500; and financial activities 3,400.Professional and business was the sole industry to post job gains year-over-year, with 1,500 new jobs. 2706

SAN DIEGO (CNS) - San Diego Unified School District officials announced they were making preparations to get children back in schools, but were looking at a timeline of "months, not weeks," before that could become a reality.The district will adopt strict new standards to protect students, staff and the community from the spread of COVID-19 when schools convene in person again, District Superintendent Cindy Marten said during a news conference Monday. The measures are being adopted and developed in consultation with experts from UCSD.In the meantime, the district will begin classes remotely this month.Conditions for reopening local schools will be stricter than state standards, will proceed in phases and will require critical protective measures including mandatory masks, proper ventilation and strict social distancing, according to district leaders.State standards for reopening schools already require a seven-day testing positivity rate of less than 8% and other factors, but the panel convened by San Diego Unified called for adding contact tracing metrics and other factors included in the County of San Diego's designated health triggers."We consulted with the world's leading experts on all aspects of this pandemic because we wanted a comprehensive set of standards to create the safest possible environment for our students and staff," said Dr. Howard Taras, UCSD professor and consulting pediatrician for San Diego Unified. "The strength in these new standards comes precisely from this combination of factors. Taken together, they represent the strictest reasonable conditions for safety when operations eventually resume."According to Taras, San Diego Unified would not consider reopening campuses to in-person study until San Diego County reports fewer than seven community outbreaks of COVID-19 in the previous week and the illness showing up in rates fewer than 100 per 100,000 over the previous two weeks, among other metrics.Marten said the district has purchased more than million in personal protective equipment and has received some 200,000 masks in child and adult sizes from the state, along with 14,000 bottles of hand sanitizer. All schools, Marten said, will follow the strict standards for reopening advised by the UCSD experts. Masks will be required for all students and staff on San Diego Unified campuses."The COVID-19 crisis has radically changed every part of our lives, and schools are no different. We must adapt to this new reality because it may be with us for years to come. That is why we are taking every step necessary to reopen in the safest, most responsible way possible," Marten said. "The fact our country has just passed another grim milestone in the history of this disease -- more than five million confirmed cases, makes it clear this is not yet the right time to begin a phased reopening, but our schools will be readywhen that time comes."President of the San Diego Education Association Kisha Borden agreed with the decision to start the new school year online."We want to get back into our classrooms with our students and we need the support of the entire community to do the right thing by wearing masks, avoiding gatherings, and listening to the science," she said. "The scientific community has made it clear there are no shortcuts on the road to safely reopening schools. We have a long road ahead of us, but we're doing the right things to keep everyone safe."Taras noted that while these guidelines were made using the best information available at the time, they were designed to be flexible with ongoing science on the spread and prevention of the pandemic."Whatever our experts say, it may change in three weeks," he said. 3711

来源：资阳报