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The Wake Forest Institute for Regenerative Medicine says it has a new use for its bioprinting system. In the past they've 3D printed normal-size organs and tissues in hopes of someday implanting them in patients.For the coronavirus, the lab is creating organs using human cells that can be as small as a pinhead. They're focusing on the organs most likely to be infected by the disease. like the lungs.“And so we've been playing with a number of agents to, on both prongs what can make it more infective, what can make it less infective to try to sort this out for the future,” Anthony Atala, director for the institute said.Atala says he hopes the system will help in testing drugs before they hit the market.Drug companies do extensive testing and clinical trials in people before releasing a new medication.Atala says sometimes those companies find no serious side effects, but then years later, discover that it's toxic to patients taking it. Atala says testing a drug using the bioprinting system can tell if a drug is toxic in weeks instead of after years on the market.“Even though we've used the tool extensively for toxicity testing, it's also a tool that can be used for screening,” Atala said. “So we can test agents that are currently being considered for testing against COVID and test the efficacy of the treatment on miniature human organs made up of normal cells”To be clear, Atala said drug tests on 3D printer organs are not meant to replace clinical trials in humans, be are an added step to better predict what will happen in those trials. 1567

The World Health Organization updated its guidelines on mask-wearing Tuesday, recommending that anyone over the age of 12 wear a mask indoor and outdoor and inside your home if it's ventilated poorly.The updated guidelines come as COVID-19 cases continue to sore in America. On Wednesday, 180,083 new cases were reported, according to data from Johns Hopkins University.According to the guidelines, in areas where COVID is spreading, WHO recommends that anyone over the age of 12 wear masks in shops, shared workplaces, and schools if they can't maintain a distance of more than 3-feet between others.They also recommend masks be worn when people visit your home if there's not adequate ventilation, or you can't be more than 3-feet or more from each other.The WHO said on top of wearing a mask, other precautions such as washing hands, avoiding touching your face, having adequate ventilation if indoors, testing, contact tracing, quarantine, and isolation should also be taken."Together, these measures are critical to prevent human-to-human transmission of COVID-19," WHO said.In areas of COVID-19 spread, the organization said healthcare workers should take part in "universal masking" in health care facilities, meaning they should wear an N95 respirator mask throughout their entire shift, including when caring for other patients.The advice applied to visitors, outpatients, and common areas such as cafeterias and staff rooms, but added administrative staff does not need to wear a mask if they are not exposed to patients.The organization also recommended that people who do vigorous physical activity should not wear masks, citing some associated risks, particularly asthma.For children, the WHO recommends children up to 5-years-old should not wear masks for source control. They added that children between the ages of 6 to 11-years-old should only wear masks if "a risk-based approach is applied.""Factors to be considered in the risk-based approach include intensity of COVID-19 transmission, child’s capacity to comply with the appropriate use of masks and availability of appropriate adult supervision, local social and cultural environment, and specific settings such as households with elderly relatives, or schools," the organization added in its guidelines. 2285

The same day that the First Baptist Church of Sutherland Springs held its first service since a gunman opened fire on parishioners last week, killing 25 people and an unborn child, residents and visitors got to see how the church had been turned into a memorial.On Sunday evening, the church opened its doors and invited the public inside the sanctuary, which had been emptied and transformed into a memorial, completely covered from floor to ceiling in white.Those who visited found 26 roses on 26 white chairs, representing each of the victims who lost their lives. 575

The Trump administration is extending a ban on green cards issued outside the United States until the end of the year and adding many temporary work visas to the freeze, including those used heavily by technology companies and multinational corporations. The administration is casting the effort as a way to free up jobs in an economy reeling from the coronavirus. A senior official who spoke to reporters on condition of anonymity estimated the restrictions will free up to 525,000 jobs for Americans. Through the first 60 days of the program, the senior administration official said the White House projects that the visa ban saved around 50,000 American jobs, but could not specify the type of jobs. The ban does not impact refugees or people already in the United States, a senior official said. The ban, while temporary, would amount to major restructuring of legal immigration if made permanent. 909

The US stock market sank deeper into the red following sluggish economic reports on Monday and bad news from a couple of blue-chip giants.The Dow fell 600 points by late afternoon, or 2.6%. The S&P 500 lost 2.6% and retreated to its lowest level of the year. And the Nasdaq joined the Dow & S&P 500 in negative territory for 2018. All three indexes have plunged about 7% so far this December.The Dow closed down 507 points for the day.And the Russell 2000 index of small-cap stocks tumbled into a bear market, marking a 20% decline from the record highs notched in late August.A weaker reading from the New York Federal Reserve about manufacturing in the Empire State and a drop in confidence from the nation's homebuilders weighed on the markets."Investors are zeroing in on this idea of slower growth for 2019," said Michael Arone, chief investment strategist at State Street Global Advisors. "More people are worried about a recession in late 2019 or 2020."The political noise in Washington isn't helping either. President Trump, in a tweet Monday morning, repeated his criticism of the Federal Reserve for its recent rate hikes. The Fed meets Wednesday and is widely expected to raise rates again.But Trump tweeted that "it is incredible that with a very strong dollar and virtually no inflation, the outside world blowing up around us, Paris is burning and China way down, the Fed is even considering yet another interest rate hike. Take the Victory!"The Fed is supposed to be politically independent. Any evidence that it might be swayed by attacks from Trump could unnerve the markets."If the Fed doesn't raise rates it will look like it's succumbing to the bullying of Trump's tweets," Arone said.But Nancy Perez, managing director at Boston Private, said the Fed is likely to slow down its pace of rate hikes in 2019 simply because the economy is slowing, not because of pressure from Trump.Perez added that the recent market turmoil is justified because investors are readjusting to this fact."We have been getting a bump in profit margins due to lower taxes but the earnings growth itself is not sustainable," Perez said. "Projections will come down and volatility will continue." 2247